Inhibitor | PKR Inhibitor  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
PKR Inhibitor   C13H8N4OS 268.30 608512-97-6 6490494 PKR Ingrand S (2007) FEBS Lett. 581(23):4473-8

Screening Results Chart

Screening Results Tables

Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
MAP4K3
-1
 3
MAP4K5
-1
 4
CLK2
0
 0
MKK1
0
 0
NUAK1
1
 0
ERK1
1
 2
GCK
1
 1
Aurora B
1
 1
MINK1
1
 0
AMPK
1
 0
AMPK (hum)
1
 0
MARK1
1
 0
DYRK1A
1
 0
DYRK2
1
 0
TAK1
1
 0
MKK2
1
 0
BRSK1
1
 0
IKK epsilon
1
 0
CDK9-Cyclin T1
2
 2
MST4
2
 1
MNK1
2
 1
PIM3
2
 1
MNK2
2
 1
ROCK 2
2
 1
MLK1
2
 0
MLK3
2
 1
PRK2
2
 0
MARK2
2
 0
DYRK3
2
 1
TrkA
2
 1
BRSK2
2
 1
VEGFR1
2
 0
PKD1
3
 1
ERK2
3
 2
Aurora A
3
 0
ERK8
3
 1
ULK2
3
 0
HIPK2
3
 0
ASK1
3
 2
MARK4
3
 1
MELK
3
 0
MST2
3
 1
SIK2
4
 0
MSK1
4
 2
SIK3
4
 1
PIM2
4
 0
ULK1
4
 0
ERK5
4
 0
CK1 delta
4
 0
RSK1
4
 0
TAO1
4
 1
IGF-1R
4
 1
PHK
4
 0
MARK3
4
 3
CHK1
4
 0
JAK2
4
 2
GSK3 beta
4
 3
CDK2-Cyclin A
5
 2
TBK1
5
 2
PIM1
5
 4
CK2
5
 0
SmMLCK
5
 1
RSK2
6
 0
IRAK1
6
 1
FGF-R1
8
 5
PDK1
8
 0
IR
8
 1
IRAK4
8
 0
JNK1
9
 0
IRR
9
 0
SGK1
10
 9
STK33
10
 1
PKA
10
 0
HIPK1
10
 1
CAMKK beta
10
 0
DAPK1
10
 0
CHK2
10
 1
p38 gamma MAPK 11 1
HIPK3 11 2
BTK 11 13
PDGFRA 12 3
S6K1 12 1
Src 12 0
JNK2 12 1
JNK3 12 1
MKK6 12 3
IKK beta 14 1
TTK 15 1
TSSK1 15 1
Lck 15 0
PAK4 15 4
RIPK2 15 1
NEK2a 16 1
OSR1 17 5
EPH-A2 17 2
p38 delta MAPK 17 1
MST3 20 24
TLK1 20 2
EPH-B3 20 7
PKC zeta 21 1
EPH-B2 22 1
DDR2 23 1
CK1 gamma 2 24 4
CAMK1 24 2
p38 beta MAPK 24 2
TIE2 25 2
BRK 25 2
EPH-B1 25 2
EIF2AK3 25 3
PKC alpha 25 3
ABL 25 3
PRAK 26 5
PLK1 27 0
EPH-B4 27 2
PAK5 28 8
SYK 30 3
EPH-A4 32 2
PKB alpha 32 1
PAK6 33 3
YES1 34 4
PKC gamma 38 3
HER4 41 12
MAPKAP-K2 42 6
TESK1 42 5
LKB1 43 0
EF2K 52 7
NEK6 56 13
PKB beta 58 22
PAK2 60 9
CSK 61 6
MEKK1 63 1
TGFBR1 63 5
MPSK1 65 17
p38 alpha MAPK 65 9
TTBK1 66 6
TTBK2 75 14
SRPK1 81 6
MAPKAP-K3 85 12
WNK1 91 3
PINK 96 14
ZAP70 98 10
Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
MAP4K3
-1
 2
ERK1
1
 0
GSK3 beta
2
 0
MKK1
2
 0
NUAK1
2
 1
MKK2
2
 0
PRK2
2
 0
CLK2
2
 1
BRSK1
3
 0
VEGFR1
3
 1
AMPK (hum)
3
 0
DYRK1A
3
 1
ERK8
3
 1
MNK1
4
 1
MST2
4
 1
GCK
4
 1
Aurora B
4
 1
MAP4K5
4
 5
MINK1
4
 0
DYRK2
4
 1
TAK1
4
 0
CDK2-Cyclin A
5
 1
ROCK 2
5
 1
AMPK
5
 2
IRAK1
6
 1
BRSK2
6
 2
MELK
6
 1
TrkA
6
 1
MLK3
6
 0
PKD1
6
 1
TBK1
7
 0
MARK3
7
 1
DYRK3
7
 1
IKK epsilon
8
 4
ERK2
8
 4
ERK5
9
 3
MARK1
9
 1
CDK9-Cyclin T1 11 0
PIM1 11 2
MLK1 11 3
MARK2 11 3
MARK4 11 0
MST3 12 1
SGK1 12 1
Aurora A 12 0
JAK2 12 1
ULK1 12 2
RSK1 13 2
MNK2 13 2
ULK2 13 1
MSK1 13 2
HIPK2 14 1
TAO1 15 3
ASK1 15 0
CHK1 16 2
PIM2 17 2
RSK2 18 0
CK1 delta 19 5
SmMLCK 19 2
SIK2 20 6
MKK6 20 6
PHK 21 1
IRR 23 1
SIK3 23 3
CK2 23 5
PDK1 25 0
PDGFRA 25 2
IRAK4 26 2
p38 gamma MAPK 26 2
FGF-R1 27 1
TTK 29 1
STK33 30 1
CAMKK beta 33 8
JNK1 34 1
IKK beta 35 4
S6K1 36 8
HIPK3 37 2
CHK2 38 2
PKA 39 2
DAPK1 39 3
JNK2 41 4
PAK4 45 3
EPH-A2 46 4
RIPK2 46 1
TSSK1 46 6
Src 46 9
MST4 47 9
HIPK1 47 2
JNK3 48 13
PKC zeta 48 5
TLK1 52 8
IGF-1R 54 6
PKC alpha 54 4
CK1 gamma 2 55 9
IR 57 3
BTK 57 7
p38 delta MAPK 57 9
OSR1 58 0
PIM3 58 12
Lck 58 4
PAK5 62 4
DDR2 62 6
EIF2AK3 62 3
EPH-B4 62 2
EPH-A4 63 4
EPH-B2 64 3
p38 beta MAPK 65 2
EPH-B1 66 10
PLK1 66 10
CAMK1 66 4
TIE2 66 8
NEK6 67 8
LKB1 67 3
PRAK 67 3
BRK 68 9
YES1 69 7
PKB beta 69 10
NEK2a 70 0
ABL 71 3
SYK 71 4
MAPKAP-K2 72 3
EPH-B3 75 28
TESK1 75 2
HER4 75 15
TTBK1 77 12
PAK6 80 10
MEKK1 81 1
TTBK2 82 6
p38 alpha MAPK 82 4
PKC gamma 82 8
PKB alpha 85 2
MPSK1 86 2
PAK2 86 3
EF2K 87 13
SRPK1 88 15
WNK1 89 17
TGFBR1 93 7
MAPKAP-K3 95 2
ZAP70 97 2
CSK 98 7
PINK 111 16