Inhibitor | 2-Aminopurine
| Compound name |
Brutto |
MW |
CAS |
PubChem CID |
Action |
Reference |
Reference |
| 2-Aminopurine |
C5H5N5 |
135.13 |
452-06-2 |
9955 |
PKR |
|
|
Screening Results Tables
Screen Conc: 100.00µM
| Kinase |
% Activity Remaining |
Standard Deviation |
| ABL |
83
|
7 |
| AMPK |
73
|
6 |
| AMPK (hum) |
80
|
11 |
| ASK1 |
44
|
3 |
| Aurora A |
64
|
3 |
| Aurora B |
23
|
2 |
| BRK |
47
|
5 |
| BRSK1 |
79
|
8 |
| BRSK2 |
81
|
3 |
| BTK |
67
|
3 |
| CAMK1 |
85
|
5 |
| CAMKK beta |
87
|
1 |
| CDK2-Cyclin A |
81
|
2 |
| CDK9-Cyclin T1 |
72
|
9 |
| CHK1 |
57
|
9 |
| CHK2 |
21
|
0 |
| CK1 delta |
24
|
4 |
| CK1 gamma 2 |
16
|
1 |
| CK2 |
89
|
5 |
| CLK2 |
37
|
4 |
| CSK |
91
|
17 |
| DAPK1 |
77
|
7 |
| DDR2 |
82
|
11 |
| DYRK1A |
64
|
3 |
| DYRK2 |
68
|
6 |
| DYRK3 |
72
|
5 |
| EF2K |
88
|
3 |
| EIF2AK3 |
89
|
0 |
| EPH-A2 |
83
|
1 |
| EPH-A4 |
84
|
4 |
| EPH-B1 |
108
|
7 |
| EPH-B2 |
95
|
10 |
| EPH-B3 |
105
|
36 |
| EPH-B4 |
90
|
10 |
| ERK1 |
78
|
8 |
| ERK2 |
78
|
0 |
| ERK5 |
67
|
1 |
| ERK8 |
79
|
10 |
| FGF-R1 |
109
|
18 |
| GCK |
20
|
0 |
| GSK3 beta |
89
|
12 |
| HER4 |
72
|
0 |
| HIPK1 |
104
|
15 |
| HIPK2 |
76
|
2 |
| HIPK3 |
92
|
2 |
| IGF-1R |
75
|
23 |
| IKK beta |
55
|
4 |
| IKK epsilon |
62
|
5 |
| IR |
106
|
8 |
| IRAK1 |
65
|
10 |
| IRAK4 |
76
|
7 |
| IRR |
73
|
5 |
| JAK2 |
30
|
0 |
| JNK1 |
81
|
6 |
| JNK2 |
83
|
8 |
| JNK3 |
83
|
6 |
| Lck |
79
|
3 |
| LKB1 |
82
|
9 |
| MAP4K3 |
50
|
6 |
| MAP4K5 |
67
|
3 |
| MAPKAP-K2 |
40
|
3 |
| MAPKAP-K3 |
70
|
3 |
| MARK1 |
67
|
0 |
| MARK2 |
69
|
2 |
| MARK3 |
61
|
5 |
| MARK4 |
74
|
5 |
| MEKK1 |
78
|
0 |
| MELK |
63
|
2 |
| MINK1 |
63
|
3 |
| MKK1 |
56
|
5 |
| MKK2 |
63
|
2 |
| MKK6 |
91
|
6 |
| MLK1 |
29
|
6 |
| MLK3 |
18
|
5 |
| MNK1 |
67
|
7 |
| MNK2 |
75
|
2 |
| MPSK1 |
89
|
4 |
| MSK1 |
84
|
4 |
| MST2 |
63
|
1 |
| MST3 |
81
|
2 |
| MST4 |
72
|
3 |
| NEK2a |
60
|
14 |
| NEK6 |
88
|
10 |
| NUAK1 |
33
|
0 |
| OSR1 |
80
|
7 |
| p38 alpha MAPK |
85
|
4 |
| p38 beta MAPK |
83
|
0 |
| p38 delta MAPK |
97
|
6 |
| p38 gamma MAPK |
75
|
0 |
| PAK2 |
100
|
10 |
| PAK4 |
44
|
5 |
| PAK5 |
64
|
0 |
| PAK6 |
82
|
5 |
| PDGFRA |
79
|
3 |
| PDK1 |
67
|
1 |
| PHK |
76
|
2 |
| PIM1 |
122
|
0 |
| PIM2 |
102
|
7 |
| PIM3 |
76
|
4 |
| PINK |
90
|
11 |
| PKA |
93
|
7 |
| PKB alpha |
99
|
5 |
| PKB beta |
83
|
7 |
| PKC alpha |
104
|
27 |
| PKC gamma |
84
|
6 |
| PKC zeta |
78
|
3 |
| PKD1 |
65
|
7 |
| PLK1 |
76
|
1 |
| PRAK |
75
|
0 |
| PRK2 |
73
|
8 |
| RIPK2 |
43
|
1 |
| ROCK 2 |
64
|
2 |
| RSK1 |
81
|
2 |
| RSK2 |
79
|
8 |
| S6K1 |
85
|
15 |
| SGK1 |
63
|
1 |
| SIK2 |
43
|
2 |
| SIK3 |
56
|
2 |
| SmMLCK |
75
|
2 |
| Src |
73
|
1 |
| SRPK1 |
96
|
1 |
| STK33 |
67
|
6 |
| SYK |
102
|
8 |
| TAK1 |
54
|
2 |
| TAO1 |
66
|
3 |
| TBK1 |
73
|
4 |
| TESK1 |
60
|
4 |
| TGFBR1 |
101
|
2 |
| TIE2 |
85
|
1 |
| TLK1 |
108
|
7 |
| TrkA |
73
|
13 |
| TSSK1 |
44
|
8 |
| TTBK1 |
80
|
12 |
| TTBK2 |
74
|
6 |
| TTK |
82
|
1 |
| ULK1 |
57
|
2 |
| ULK2 |
69
|
0 |
| VEGFR1 |
29
|
3 |
| WNK1 |
87
|
2 |
| YES1 |
94
|
6 |
| ZAP70 |
101
|
4 |
