Inhibitor | CGP-57380  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
CK1 delta	4	0
MNK1	6	1
BRSK2	10	0
Aurora B	11	0
MKK1	12	0
PIM3	14	0
Lck	14	0
YES1	15	4
ERK8	16	1
ERK1	21	2
CDK2-Cyclin A	21	1
CHK1	21	1
MNK2	24	11
EPH-A2	25	1
Src	25	4
PHK	27	3
DYRK2	29	0
FGF-R1	30	0
PIM1	31	6
PDK1	34	7
DYRK3	36	8
IRR	38	6
CHK2	39	0
RSK1	41	1
SGK1	41	2
MST2	46	1
RSK2	46	9
Aurora C	47	5
MARK3	48	11
MST4	51	2
p38 alpha MAPK	54	0
CK2	55	7
CAMK1	55	2
S6K1	59	8
MELK	61	3
DYRK1A	62	10
NEK2a	62	0
AMPK	64	6
CAMKK beta	64	2
IKK beta	66	0
GSK3 beta	68	4
TBK1	68	3
ERK2	70	13
PLK1	71	13
PKC alpha	72	9
PAK4	74	9
SRPK1	75	4
PKD1	75	3
PKA	76	4
PRK2	76	4
ROCK 2	76	9
PAK5	79	5
SYK	81	4
CSK	82	8
p38 gamma MAPK	82	12
HIPK2	83	0
PIM2	83	7
p38 beta MAPK	83	7
PKB beta	85	3
SmMLCK	85	13
HIPK3	91	5
MSK1	93	0
IKK epsilon	93	6
PKC zeta	96	5
NEK7	100	5
MAPKAP-K2	100	6
EF2K	103	10
PRAK	103	7
PAK6	106	3
JNK1	108	4
p38 delta MAPK	111	10
PKB alpha	116	4
JNK3	116	14
JNK2	121	4
MAPKAP-K3	125	12
NEK6	127	5

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
CK1 delta	30	3
MNK1	35	2
BRSK2	39	8
RSK1	51	2
PIM3	54	2
MNK2	56	2
MKK1	56	1
SGK1	57	2
YES1	59	5
PHK	61	3
Aurora B	64	4
DYRK3	67	5
Src	67	6
CSK	67	1
MELK	68	6
Lck	70	6
PKA	71	5
MST2	72	6
FGF-R1	73	1
PDK1	74	3
IRR	75	10
PAK4	76	4
DYRK2	77	3
ERK1	78	4
PAK6	79	5
MST4	79	9
MARK3	80	1
CDK2-Cyclin A	81	1
p38 alpha MAPK	82	6
Aurora C	82	4
ERK2	82	3
RSK2	83	1
PIM1	83	5
CHK1	84	6
IKK beta	85	3
EPH-A2	85	1
MSK1	85	4
ERK8	86	6
PKD1	86	4
PAK5	87	1
GSK3 beta	87	6
CK2	87	3
PKC zeta	88	5
EF2K	90	2
PKB beta	90	5
CAMKK beta	90	5
PRK2	90	5
PKC alpha	90	6
PIM2	90	1
DYRK1A	91	6
NEK2a	91	2
PLK1	91	2
NEK6	93	1
HIPK2	94	1
CAMK1	95	1
CHK2	95	2
PRAK	96	4
PKB alpha	96	4
JNK3	96	0
ROCK 2	97	5
JNK2	97	4
S6K1	98	4
SRPK1	98	6
SmMLCK	99	1
p38 delta MAPK	101	5
AMPK	101	8
p38 beta MAPK	102	1
CAMKK alpha	102	2
p38 gamma MAPK	102	5
JNK1	102	7
NEK7	103	7
MAPKAP-K3	104	4
TBK1	104	1
HIPK3	106	0
IKK epsilon	106	3
MAPKAP-K2	118	2
SYK	131	3