Inhibitor | CGP-57380  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	101	8
Aurora B	64	4
Aurora C	82	4
BRSK2	39	8
CAMK1	95	1
CAMKK alpha	102	2
CAMKK beta	90	5
CDK2-Cyclin A	81	1
CHK1	84	6
CHK2	95	2
CK1 delta	30	3
CK2	87	3
CSK	67	1
DYRK1A	91	6
DYRK2	77	3
DYRK3	67	5
EF2K	90	2
EPH-A2	85	1
ERK1	78	4
ERK2	82	3
ERK8	86	6
FGF-R1	73	1
GSK3 beta	87	6
HIPK2	94	1
HIPK3	106	0
IKK beta	85	3
IKK epsilon	106	3
IRR	75	10
JNK1	102	7
JNK2	97	4
JNK3	96	0
Lck	70	6
MAPKAP-K2	118	2
MAPKAP-K3	104	4
MARK3	80	1
MELK	68	6
MKK1	56	1
MNK1	35	2
MNK2	56	2
MSK1	85	4
MST2	72	6
MST4	79	9
NEK2a	91	2
NEK6	93	1
NEK7	103	7
p38 alpha MAPK	82	6
p38 beta MAPK	102	1
p38 delta MAPK	101	5
p38 gamma MAPK	102	5
PAK4	76	4
PAK5	87	1
PAK6	79	5
PDK1	74	3
PHK	61	3
PIM1	83	5
PIM2	90	1
PIM3	54	2
PKA	71	5
PKB alpha	96	4
PKB beta	90	5
PKC alpha	90	6
PKC zeta	88	5
PKD1	86	4
PLK1	91	2
PRAK	96	4
PRK2	90	5
ROCK 2	97	5
RSK1	51	2
RSK2	83	1
S6K1	98	4
SGK1	57	2
SmMLCK	99	1
Src	67	6
SRPK1	98	6
SYK	131	3
TBK1	104	1
YES1	59	5

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	64	6
Aurora B	11	0
Aurora C	47	5
BRSK2	10	0
CAMK1	55	2
CAMKK beta	64	2
CDK2-Cyclin A	21	1
CHK1	21	1
CHK2	39	0
CK1 delta	4	0
CK2	55	7
CSK	82	8
DYRK1A	62	10
DYRK2	29	0
DYRK3	36	8
EF2K	103	10
EPH-A2	25	1
ERK1	21	2
ERK2	70	13
ERK8	16	1
FGF-R1	30	0
GSK3 beta	68	4
HIPK2	83	0
HIPK3	91	5
IKK beta	66	0
IKK epsilon	93	6
IRR	38	6
JNK1	108	4
JNK2	121	4
JNK3	116	14
Lck	14	0
MAPKAP-K2	100	6
MAPKAP-K3	125	12
MARK3	48	11
MELK	61	3
MKK1	12	0
MNK1	6	1
MNK2	24	11
MSK1	93	0
MST2	46	1
MST4	51	2
NEK2a	62	0
NEK6	127	5
NEK7	100	5
p38 alpha MAPK	54	0
p38 beta MAPK	83	7
p38 delta MAPK	111	10
p38 gamma MAPK	82	12
PAK4	74	9
PAK5	79	5
PAK6	106	3
PDK1	34	7
PHK	27	3
PIM1	31	6
PIM2	83	7
PIM3	14	0
PKA	76	4
PKB alpha	116	4
PKB beta	85	3
PKC alpha	72	9
PKC zeta	96	5
PKD1	75	3
PLK1	71	13
PRAK	103	7
PRK2	76	4
ROCK 2	76	9
RSK1	41	1
RSK2	46	9
S6K1	59	8
SGK1	41	2
SmMLCK	85	13
Src	25	4
SRPK1	75	4
SYK	81	4
TBK1	68	3
YES1	15	4