Inhibitor | CCT250862  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
CCT250862   NEK

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ABL 17 1
AMPK 24 4
AMPK (hum) 15 2
ASK1 73 11
Aurora A 113 5
Aurora B 54 16
BRK 68 4
BRSK1 23 6
BRSK2 21 2
BTK 37 3
CAMK1 105 2
CAMKK beta 38 44
CDK2-Cyclin A 41 7
CDK9-Cyclin T1 54 9
CHK1 85 3
CHK2 51 5
CK1 delta
9
 1
CK1 gamma 2 39 5
CK2 96 8
CLK2
2
 0
CSK 55 2
DAPK1 81 6
DDR2 28 2
DYRK1A
4
 0
DYRK2 92 6
DYRK3 38 2
EF2K 85 4
EIF2AK3 100 2
EPH-A2 69 2
EPH-A4 64 13
EPH-B1 114 10
EPH-B2 40 5
EPH-B3 91 14
EPH-B4 94 11
ERK1 78 3
ERK2 74 6
ERK5 36 7
ERK8 15 7
FGF-R1 17 1
GCK
3
 0
GSK3 beta
5
 1
HER4 93 4
HIPK1 30 12
HIPK2 23 6
HIPK3 65 14
IGF-1R 17 7
IKK beta 91 4
IKK epsilon 32 3
IR 64 8
IRAK1 11 3
IRAK4 33 7
IRR 16 2
JAK2 27 0
JNK1 76 2
JNK2 70 3
JNK3 86 10
Lck
9
 1
LKB1 46 3
MAP4K3
6
 2
MAP4K5
7
 1
MAPKAP-K2 91 3
MAPKAP-K3 99 0
MARK1 46 3
MARK2 34 3
MARK3 26 1
MARK4 45 7
MEKK1 85 2
MELK 27 5
MINK1
6
 1
MKK1 84 3
MKK2 91 3
MKK6 82 7
MLK1 17 7
MLK3
4
 1
MNK1 37 8
MNK2 25 2
MPSK1 100 1
MSK1 29 5
MST2 23 11
MST3 60 2
MST4 41 11
NEK2a 55 15
NEK6 106 3
NUAK1
2
 1
OSR1 68 5
p38 alpha MAPK 108 24
p38 beta MAPK 86 5
p38 delta MAPK 80 0
p38 gamma MAPK 90 6
PAK2 87 6
PAK4 84 1
PAK5 97 10
PAK6 95 3
PDGFRA 70 11
PDK1 74 10
PHK 24 0
PIM1 48 5
PIM2 95 2
PIM3 51 3
PKA 86 4
PKB alpha 89 2
PKB beta 95 25
PKC alpha 32 3
PKC gamma 36 6
PKC zeta 68 9
PKD1 31 2
PLK1 81 17
PRAK 89 5
PRK2 17 1
RIPK2 11 2
ROCK 2 89 10
RSK1 42 16
RSK2 62 1
S6K1 21 2
SGK1 54 2
SIK2 14 5
SIK3 56 0
SmMLCK 18 2
Src 13 1
SRPK1 78 3
STK33 25 2
SYK 94 1
TAK1
6
 0
TAO1 25 0
TBK1 42 10
TESK1 76 11
TGFBR1 42 1
TIE2 41 1
TLK1 96 3
TrkA
10
 1
TSSK1 51 1
TTBK1 98 12
TTBK2 94 3
TTK 62 1
ULK1 67 8
ULK2 37 3
VEGFR1
6
 0
WNK1 108 8
YES1
6
 1
ZAP70 95 14