Inhibitor | Torin1  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
Torin1   C35H28F3N5O2 607.62 1222998-36-8 49836027 mTOR Liu Q. (2012) J Biol Chem. 287 9742-52

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 78 3
Aurora A 88 4
Aurora B 107 2
BRSK1 99 4
BRSK2 102 5
BTK 104 5
CAMK1 104 23
CAMKK beta 95 2
CDK2-Cyclin A 108 4
CHK1 106 9
CHK2 90 2
CK1 delta 93 15
CK2 89 1
CSK 101 2
DYRK1A 92 3
DYRK2 99 1
DYRK3 88 6
EF2K 118 8
EPH-A2 120 4
EPH-B3 115 2
ERK1 99 8
ERK2 102 4
ERK8 78 4
FGF-R1 110 8
GCK 69 1
GSK3 beta 79 6
HER4 110 11
HIPK1 76 4
HIPK2 96 0
HIPK3 107 17
IGF-1R 100 9
IKK beta 109 5
IR 93 8
IRAK4 112 7
IRR 85 3
JNK1 98 21
JNK2 98 10
JNK3 99 27
Lck 93 8
LKB1 96 3
MAPKAP-K2 102 4
MAPKAP-K3 113 3
MARK2 117 10
MARK3 99 1
MARK4 94 15
MELK 63 6
MINK1 69 2
MKK1 69 11
MLK1 92 6
MLK3 99 5
MNK1 93 10
MNK2 112 2
MSK1 86 5
MST2 97 21
MST4 96 11
NEK2a 88 1
NEK6 100 14
NUAK1 101 10
p38 alpha MAPK 95 4
p38 beta MAPK 83 5
p38 delta MAPK 106 4
p38 gamma MAPK 103 4
PAK2 93 3
PAK4 110 12
PAK5 120 33
PAK6 110 0
PDK1 100 1
PHK 110 10
PIM1 82 4
PIM2 86 5
PIM3 85 2
PKA 106 9
PKB alpha 94 6
PKB beta 95 0
PKC alpha 83 4
PKC zeta 121 13
PKD1 117 7
PLK1 94 16
PRAK 118 20
PRK2 97 1
RIPK2 81 2
ROCK 2 96 19
RSK1 93 11
RSK2 96 14
S6K1 97 13
SGK1 79 5
SmMLCK 94 5
Src 60 6
SRPK1 107 8
SYK 131 14
TBK1 96 15
TTK 79 3
VEGFR1 108 1
YES1 113 2
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 93 6
Aurora A 68 9
Aurora B 90 1
BRSK1 94 17
BRSK2 104 7
BTK 56 0
CAMK1 77 15
CAMKK beta 81 4
CDK2-Cyclin A 77 6
CHK1 125 9
CHK2 83 4
CK1 delta 104 0
CK2 95 0
CSK 83 4
DYRK1A 75 0
DYRK2 99 16
DYRK3 52 3
EF2K 111 7
EPH-A2 87 0
EPH-B3 94 6
ERK1 96 10
ERK2 90 4
ERK8 46 7
FGF-R1 79 8
GCK 25 1
GSK3 beta 49 1
HER4 111 5
HIPK1 85 15
HIPK2 88 6
HIPK3 91 4
IGF-1R 93 1
IKK beta 63 0
IKK epsilon 85 7
IR 87 10
IRAK4 76 3
IRR 73 7
JNK1 87 10
JNK2 84 3
JNK3 79 3
Lck 78 4
LKB1 80 0
MAPKAP-K2 108 5
MAPKAP-K3 105 10
MARK2 102 23
MARK3 98 8
MARK4 97 5
MELK 17 3
MINK1 14 1
MKK1 22 6
MLK1 48 4
MLK3 86 3
MNK1 96 3
MNK2 96 7
MSK1 62 6
MST2 79 3
MST4 89 7
NEK2a 99 4
NEK6 69 11
NUAK1 79 12
p38 alpha MAPK 99 6
p38 beta MAPK 78 3
p38 delta MAPK 97 10
p38 gamma MAPK 129 12
PAK2 82 5
PAK4 66 6
PAK5 61 20
PAK6 80 0
PDK1 98 1
PHK 99 6
PIM1 24 3
PIM2 96 4
PIM3 30 0
PKA 96 7
PKB alpha 71 6
PKB beta 84 1
PKC alpha 68 3
PKC zeta 106 7
PKD1 101 3
PLK1 84 12
PRAK 49 1
PRK2 114 6
RIPK2 64 2
ROCK 2 101 9
RSK1 71 15
RSK2 81 10
S6K1 81 1
SGK1 60 14
SmMLCK 83 1
Src 52 5
SRPK1 110 4
SYK 68 2
TBK1 87 5
TTK 71 1
VEGFR1 84 6
YES1 78 3