Inhibitor | HG-10-102-01  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
HG-10-102-01   LRRK2 Choi H.G. (2012) ACS Med. Chem. Lett.

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ZAP70 97 4
YES1 80 3
WNK1 62 20
VEGFR1 65 25
ULK2 97 9
ULK1 62 10
TTK 71 0
TTBK2 115 11
TTBK1 88 8
TSSK1 51 3
TrkA 80 14
TLK1 61 7
TIE2 79 3
TESK1 90 0
TBK1 86 3
TAO1 81 22
TAK1 74 16
SYK 68 17
STK33 61 1
SRPK1 96 1
Src 84 6
SmMLCK 83 1
SIK3 93 6
SIK2 49 11
SGK1 94 3
S6K1 70 15
RSK2 92 7
RSK1 87 10
ROCK 2 87 7
RIPK2 79 6
PRK2 102 12
PRAK 91 0
PLK1 97 23
PKD1 70 5
PKC zeta 99 10
PKC gamma 93 2
PKC alpha 66 6
PKB beta 95 11
PKB alpha 53 1
PKA 85 10
PIM3 77 0
PIM2 94 13
PIM1 96 8
PHK 68 11
PDK1 102 11
PDGFRA 79 0
PAK6 90 8
PAK5 88 3
PAK4 87 1
PAK2 97 4
p38 gamma MAPK 88 21
p38 delta MAPK 87 0
p38 beta MAPK 57 11
p38 alpha MAPK 71 8
OSR1 108 1
NUAK1 43 1
NEK6 73 25
NEK2a 63 1
MST4 101 1
MST3 83 9
MST2 85 17
MSK1 104 8
MPSK1 100 2
MNK2 20 9
MNK1 71 11
MLK3 75 10
MLK1 38 3
MKK6 74 29
MKK2 91 17
MKK1 106 15
MINK1 86 4
MELK 88 21
MEKK1 93 2
MARK4 82 7
MARK3 91 1
MARK2 85 7
MARK1 91 9
MAPKAP-K3 120 81
MAPKAP-K2 88 4
MAP4K5 83 7
MAP4K3 94 11
LKB1 92 1
Lck 92 4
JNK3 60 1
JNK2 76 10
JNK1 89 8
JAK2 83 8
IRR 126 5
IRAK4 90 6
IRAK1 84 21
IR 86 4
IKK epsilon 77 31
IKK beta 82 2
IGF-1R 100 3
HIPK3 85 0
HIPK2 77 23
HIPK1 77 10
HER4 89 4
GSK3 beta 100 1
GCK 108 10
FGF-R1 89 6
ERK8 74 26
ERK2 79 5
ERK1 95 16
EPH-B4 94 12
EPH-B3 67 2
EPH-B2 105 7
EPH-B1 115 1
EPH-A4 100 4
EPH-A2 93 9
EIF2AK3 99 19
EF2K 83 3
DYRK3 84 1
DYRK2 44 7
DYRK1A 79 12
DDR2 103 16
DAPK1 61 13
CSK 97 1
CLK2 91 1
CK2 50 8
CK1 gamma 2 96 10
CK1 delta 44 7
CHK2 52 2
CHK1 65 29
CDK9-Cyclin T1 89 7
CDK2-Cyclin A 82 2
CAMKK beta 52 13
CAMK1 85 1
BTK 83 8
BRSK2 78 11
BRSK1 59 18
BRK 56 2
Aurora B 83 1
Aurora A 56 4
ASK1 70 3
AMPK (hum) 91 7
AMPK 89 5
ABL 84 7
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ZAP70 81 7
YES1 90 5
WNK1 99 6
VEGFR1 35 2
ULK2 84 6
ULK1 85 2
TTK 57 5
TTBK2 97 12
TTBK1 91 4
TSSK1 19 1
TrkA 87 1
TLK1 100 9
TIE2 90 0
TESK1 83 15
TBK1 42 1
TAO1 93 4
TAK1 25 8
SYK 85 9
STK33 28 1
SRPK1 94 22
Src 79 0
SmMLCK 55 3
SIK3 82 3
SIK2 47 0
SGK1 91 1
S6K1 67 15
RSK2 65 10
RSK1 54 2
ROCK 2 71 2
RIPK2 80 2
PRK2 92 10
PRAK 44 1
PLK1 105 4
PKD1 25 4
PKC zeta 101 9
PKC gamma 108 6
PKC alpha 87 9
PKB beta 64 8
PKB alpha 85 1
PKA 94 8
PIM3 72 4
PIM2 97 13
PIM1 99 0
PHK 23 4
PDK1 89 8
PDGFRA 56 1
PAK6 98 9
PAK5 80 0
PAK4 84 8
PAK2 105 4
p38 gamma MAPK 94 11
p38 delta MAPK 86 3
p38 beta MAPK 93 6
p38 alpha MAPK 93 10
OSR1 82 10
NUAK1 20 6
NEK6 69 19
NEK2a 90 13
MST4 106 9
MST3 80 5
MST2 73 10
MSK1 84 11
MPSK1 97 7
MNK2
7
 2
MNK1 44 6
MLK3 43 9
MLK1 18 0
MKK6 65 7
MKK2 86 10
MKK1 93 7
MINK1 96 14
MELK 98 3
MEKK1 98 7
MARK4 72 6
MARK3 78 2
MARK2 90 6
MARK1 84 7
MAPKAP-K3 81 2
MAPKAP-K2 102 2
MAP4K5 82 7
MAP4K3 70 9
LKB1 90 8
Lck 95 5
JNK3 29 10
JNK2 46 3
JNK1 37 2
JAK2 80 18
IRR 97 9
IRAK4 86 3
IRAK1 83 11
IR 50 7
IKK epsilon 75 2
IKK beta 80 7
IGF-1R 51 7
HIPK3 80 5
HIPK2 88 6
HIPK1 94 7
HER4 94 2
GSK3 beta 98 6
GCK 79 11
FGF-R1 86 10
ERK8 82 5
ERK2 69 11
ERK1 104 22
EPH-B4 113 7
EPH-B3 101 17
EPH-B2 103 8
EPH-B1 86 5
EPH-A4 94 7
EPH-A2 97 4
EIF2AK3 97 2
EF2K 86 9
DYRK3 76 3
DYRK2 21 6
DYRK1A 80 2
DDR2 90 16
DAPK1 23 5
CSK 103 11
CLK2 76 5
CK2 88 1
CK1 gamma 2 93 2
CK1 delta 89 9
CHK2 96 15
CHK1 45 4
CDK9-Cyclin T1 83 3
CDK2-Cyclin A 65 4
CAMKK beta 31 3
CAMK1 66 3
BTK 88 2
BRSK2 64 5
BRSK1 78 0
BRK 39 1
Aurora B 42 4
Aurora A 45 9
ASK1 54 3
AMPK (hum) 71 6
AMPK 80 1
ABL 86 9