Inhibitor | HG-10-102-01  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	84	7
AMPK	89	5
AMPK (hum)	91	7
ASK1	70	3
Aurora A	56	4
Aurora B	83	1
BRK	56	2
BRSK1	59	18
BRSK2	78	11
BTK	83	8
CAMK1	85	1
CAMKK beta	52	13
CDK2-Cyclin A	82	2
CDK9-Cyclin T1	89	7
CHK1	65	29
CHK2	52	2
CK1 delta	44	7
CK1 gamma 2	96	10
CK2	50	8
CLK2	91	1
CSK	97	1
DAPK1	61	13
DDR2	103	16
DYRK1A	79	12
DYRK2	44	7
DYRK3	84	1
EF2K	83	3
EIF2AK3	99	19
EPH-A2	93	9
EPH-A4	100	4
EPH-B1	115	1
EPH-B2	105	7
EPH-B3	67	2
EPH-B4	94	12
ERK1	95	16
ERK2	79	5
ERK8	74	26
FGF-R1	89	6
GCK	108	10
GSK3 beta	100	1
HER4	89	4
HIPK1	77	10
HIPK2	77	23
HIPK3	85	0
IGF-1R	100	3
IKK beta	82	2
IKK epsilon	77	31
IR	86	4
IRAK1	84	21
IRAK4	90	6
IRR	126	5
JAK2	83	8
JNK1	89	8
JNK2	76	10
JNK3	60	1
Lck	92	4
LKB1	92	1
MAP4K3	94	11
MAP4K5	83	7
MAPKAP-K2	88	4
MAPKAP-K3	120	81
MARK1	91	9
MARK2	85	7
MARK3	91	1
MARK4	82	7
MEKK1	93	2
MELK	88	21
MINK1	86	4
MKK1	106	15
MKK2	91	17
MKK6	74	29
MLK1	38	3
MLK3	75	10
MNK1	71	11
MNK2	20	9
MPSK1	100	2
MSK1	104	8
MST2	85	17
MST3	83	9
MST4	101	1
NEK2a	63	1
NEK6	73	25
NUAK1	43	1
OSR1	108	1
p38 alpha MAPK	71	8
p38 beta MAPK	57	11
p38 delta MAPK	87	0
p38 gamma MAPK	88	21
PAK2	97	4
PAK4	87	1
PAK5	88	3
PAK6	90	8
PDGFRA	79	0
PDK1	102	11
PHK	68	11
PIM1	96	8
PIM2	94	13
PIM3	77	0
PKA	85	10
PKB alpha	53	1
PKB beta	95	11
PKC alpha	66	6
PKC gamma	93	2
PKC zeta	99	10
PKD1	70	5
PLK1	97	23
PRAK	91	0
PRK2	102	12
RIPK2	79	6
ROCK 2	87	7
RSK1	87	10
RSK2	92	7
S6K1	70	15
SGK1	94	3
SIK2	49	11
SIK3	93	6
SmMLCK	83	1
Src	84	6
SRPK1	96	1
STK33	61	1
SYK	68	17
TAK1	74	16
TAO1	81	22
TBK1	86	3
TESK1	90	0
TIE2	79	3
TLK1	61	7
TrkA	80	14
TSSK1	51	3
TTBK1	88	8
TTBK2	115	11
TTK	71	0
ULK1	62	10
ULK2	97	9
VEGFR1	65	25
WNK1	62	20
YES1	80	3
ZAP70	97	4

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	86	9
AMPK	80	1
AMPK (hum)	71	6
ASK1	54	3
Aurora A	45	9
Aurora B	42	4
BRK	39	1
BRSK1	78	0
BRSK2	64	5
BTK	88	2
CAMK1	66	3
CAMKK beta	31	3
CDK2-Cyclin A	65	4
CDK9-Cyclin T1	83	3
CHK1	45	4
CHK2	96	15
CK1 delta	89	9
CK1 gamma 2	93	2
CK2	88	1
CLK2	76	5
CSK	103	11
DAPK1	23	5
DDR2	90	16
DYRK1A	80	2
DYRK2	21	6
DYRK3	76	3
EF2K	86	9
EIF2AK3	97	2
EPH-A2	97	4
EPH-A4	94	7
EPH-B1	86	5
EPH-B2	103	8
EPH-B3	101	17
EPH-B4	113	7
ERK1	104	22
ERK2	69	11
ERK8	82	5
FGF-R1	86	10
GCK	79	11
GSK3 beta	98	6
HER4	94	2
HIPK1	94	7
HIPK2	88	6
HIPK3	80	5
IGF-1R	51	7
IKK beta	80	7
IKK epsilon	75	2
IR	50	7
IRAK1	83	11
IRAK4	86	3
IRR	97	9
JAK2	80	18
JNK1	37	2
JNK2	46	3
JNK3	29	10
Lck	95	5
LKB1	90	8
MAP4K3	70	9
MAP4K5	82	7
MAPKAP-K2	102	2
MAPKAP-K3	81	2
MARK1	84	7
MARK2	90	6
MARK3	78	2
MARK4	72	6
MEKK1	98	7
MELK	98	3
MINK1	96	14
MKK1	93	7
MKK2	86	10
MKK6	65	7
MLK1	18	0
MLK3	43	9
MNK1	44	6
MNK2	7	2
MPSK1	97	7
MSK1	84	11
MST2	73	10
MST3	80	5
MST4	106	9
NEK2a	90	13
NEK6	69	19
NUAK1	20	6
OSR1	82	10
p38 alpha MAPK	93	10
p38 beta MAPK	93	6
p38 delta MAPK	86	3
p38 gamma MAPK	94	11
PAK2	105	4
PAK4	84	8
PAK5	80	0
PAK6	98	9
PDGFRA	56	1
PDK1	89	8
PHK	23	4
PIM1	99	0
PIM2	97	13
PIM3	72	4
PKA	94	8
PKB alpha	85	1
PKB beta	64	8
PKC alpha	87	9
PKC gamma	108	6
PKC zeta	101	9
PKD1	25	4
PLK1	105	4
PRAK	44	1
PRK2	92	10
RIPK2	80	2
ROCK 2	71	2
RSK1	54	2
RSK2	65	10
S6K1	67	15
SGK1	91	1
SIK2	47	0
SIK3	82	3
SmMLCK	55	3
Src	79	0
SRPK1	94	22
STK33	28	1
SYK	85	9
TAK1	25	8
TAO1	93	4
TBK1	42	1
TESK1	83	15
TIE2	90	0
TLK1	100	9
TrkA	87	1
TSSK1	19	1
TTBK1	91	4
TTBK2	97	12
TTK	57	5
ULK1	85	2
ULK2	84	6
VEGFR1	35	2
WNK1	99	6
YES1	90	5
ZAP70	81	7