Inhibitor | JNKIN8  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
ABL	97	3
AMPK	101	12
ASK1	100	13
Aurora A	97	2
Aurora B	87	2
BRK	94	42
BRSK1	99	8
BRSK2	87	7
BTK	96	5
CAMK1	92	1
CAMKK beta	133	24
CDK2-Cyclin A	107	4
CDK9-Cyclin T1	85	18
CHK1	102	19
CHK2	102	10
CK1 delta	89	13
CK1 gamma 2	109	6
CK2	93	4
CLK2	102	14
CSK	110	16
DAPK1	102	7
DDR2	106	5
DYRK1A	98	0
DYRK2	73	0
DYRK3	94	6
EF2K	98	6
EIF2AK3	103	6
EPH-A2	118	13
EPH-A4	87	4
EPH-B1	97	4
EPH-B2	101	11
EPH-B3	112	20
EPH-B4	97	3
ERK1	103	1
ERK2	110	15
ERK8	90	4
FGF-R1	103	6
GCK	98	9
GSK3 beta	114	2
HER4	102	5
HIPK1	103	19
HIPK2	92	10
HIPK3	97	3
IGF-1R	106	37
IKK beta	62	5
IKK epsilon	92	8
IR	102	9
IRAK1	93	18
IRAK4	88	24
IRR	93	1
JAK2	100	2
JNK1	13	2
JNK2	87	21
JNK3	14	1
Lck	96	0
LKB1	106	6
MAPKAP-K2	102	6
MAPKAP-K3	91	25
MARK1	114	7
MARK2	99	4
MARK3	92	5
MARK4	101	16
MEKK1	95	17
MELK	91	3
MINK1	94	6
MKK1	107	6
MKK2	98	19
MKK6	100	12
MLK1	98	7
MLK3	95	0
MNK1	86	27
MNK2	84	6
MPSK1	110	8
MSK1	91	11
MST2	100	23
MST3	85	3
MST4	96	0
NEK2a	105	9
NEK6	95	18
NUAK1	79	10
OSR1	96	0
p38 alpha MAPK	105	2
p38 beta MAPK	90	7
p38 delta MAPK	96	10
p38 gamma MAPK	99	6
PAK2	99	9
PAK4	98	21
PAK5	100	7
PAK6	110	11
PDK1	84	8
PHK	85	19
PIM1	104	6
PIM2	104	9
PIM3	103	26
PKA	105	14
PKB alpha	102	6
PKB beta	99	11
PKC alpha	93	5
PKC gamma	92	6
PKC zeta	116	3
PKD1	99	15
PLK1	98	7
PRAK	92	10
PRK2	112	9
RIPK2	82	4
ROCK 2	86	12
RSK1	89	5
RSK2	82	2
S6K1	98	4
SGK1	117	20
SIK2	100	3
SIK3	88	1
SmMLCK	97	0
Src	85	8
SRPK1	97	1
STK33	99	16
SYK	103	10
TAK1	90	5
TAO1	124	5
TBK1	100	20
TESK1	89	10
TIE2	105	1
TLK1	99	5
TrkA	102	30
TSSK1	91	7
TTBK1	92	2
TTK	85	3
ULK1	27	2
ULK2	28	4
VEGFR1	100	2
WNK1	102	3
YES1	87	13
ZAP70	105	10

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	86	7
AMPK	77	8
ASK1	91	13
Aurora A	91	6
Aurora B	86	9
BRK	75	8
BRSK1	87	11
BRSK2	77	13
BTK	80	12
CAMK1	86	7
CAMKK beta	63	11
CDK2-Cyclin A	92	8
CDK9-Cyclin T1	80	4
CHK1	87	13
CHK2	72	10
CK1 delta	57	0
CK1 gamma 2	87	8
CK2	77	4
CLK2	88	19
CSK	93	1
DAPK1	90	3
DDR2	97	9
DYRK1A	84	3
DYRK2	72	8
DYRK3	80	4
EF2K	95	4
EIF2AK3	93	11
EPH-A2	111	17
EPH-A4	80	10
EPH-B1	95	1
EPH-B2	97	11
EPH-B3	105	18
EPH-B4	98	15
ERK1	99	2
ERK2	100	6
ERK8	64	9
FGF-R1	82	12
GCK	73	0
GSK3 beta	90	6
HER4	98	15
HIPK1	87	9
HIPK2	99	14
HIPK3	90	5
IGF-1R	87	5
IKK beta	74	1
IKK epsilon	94	17
IR	80	9
IRAK1	63	5
IRAK4	86	0
IRR	88	22
JAK2	94	5
JNK1	6	2
JNK2	17	3
JNK3	13	4
Lck	92	10
LKB1	95	12
MAPKAP-K2	100	4
MAPKAP-K3	90	8
MARK1	105	20
MARK2	85	7
MARK3	93	2
MARK4	84	5
MEKK1	82	3
MELK	63	0
MINK1	78	7
MKK1	96	10
MKK2	92	3
MKK6	95	4
MLK1	88	1
MLK3	94	13
MNK1	88	12
MNK2	67	13
MPSK1	101	17
MSK1	80	0
MST2	72	12
MST3	82	2
MST4	79	3
NEK2a	100	16
NEK6	87	2
NUAK1	49	7
OSR1	91	10
p38 alpha MAPK	110	2
p38 beta MAPK	88	8
p38 delta MAPK	80	12
p38 gamma MAPK	95	2
PAK2	90	3
PAK4	78	7
PAK5	82	7
PAK6	96	1
PDK1	85	6
PHK	86	5
PIM1	89	8
PIM2	99	9
PIM3	83	10
PKA	93	6
PKB alpha	98	5
PKB beta	91	7
PKC alpha	90	9
PKC gamma	91	8
PKC zeta	89	7
PKD1	89	1
PLK1	94	13
PRAK	82	4
PRK2	95	4
RIPK2	49	8
ROCK 2	80	1
RSK1	81	7
RSK2	76	7
S6K1	93	1
SGK1	102	28
SIK2	105	14
SIK3	79	2
SmMLCK	96	2
Src	50	7
SRPK1	84	10
STK33	90	6
SYK	88	19
TAK1	66	6
TAO1	97	18
TBK1	106	2
TESK1	93	8
TIE2	98	14
TLK1	100	2
TrkA	92	2
TSSK1	86	9
TTBK1	83	10
TTK	65	11
ULK1	67	0
ULK2	69	5
VEGFR1	53	7
WNK1	107	15
YES1	39	9
ZAP70	95	20