Inhibitor | BX-320  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	46	3
Aurora B	6	2
Aurora C	8	0
BRSK2	72	3
CAMK1	71	4
CAMKK alpha	89	13
CAMKK beta	62	9
CDK2-Cyclin A	90	6
CHK1	71	4
CHK2	99	2
CK1 delta	89	6
CK2	105	10
CSK	93	14
DYRK1A	86	3
DYRK2	92	0
DYRK3	86	9
EF2K	110	7
EPH-A2	81	5
ERK1	81	8
ERK2	84	0
ERK8	57	10
FGF-R1	44	3
GSK3 beta	55	1
HIPK2	96	8
HIPK3	101	6
IKK beta	95	9
IKK epsilon	37	4
IRR	88	1
JNK1	106	8
JNK2	95	4
JNK3	97	5
Lck	76	4
MAPKAP-K2	102	7
MAPKAP-K3	106	4
MARK3	35	3
MELK	56	10
MKK1	60	6
MNK1	88	13
MNK2	71	5
MSK1	91	0
MST2	97	3
MST4	102	3
NEK2a	94	3
NEK6	117	14
NEK7	116	14
p38 alpha MAPK	107	6
p38 beta MAPK	72	7
p38 delta MAPK	93	2
p38 gamma MAPK	86	3
PAK4	78	7
PAK5	93	1
PAK6	88	2
PDK1	33	0
PHK	101	1
PIM1	86	1
PIM2	104	9
PIM3	97	2
PKA	99	1
PKB alpha	82	14
PKB beta	104	0
PKC alpha	98	1
PKC zeta	82	5
PKD1	85	15
PLK1	96	7
PRAK	82	14
PRK2	71	1
ROCK 2	77	4
RSK1	89	3
RSK2	88	2
S6K1	100	7
SGK1	75	5
SmMLCK	103	4
Src	84	0
SRPK1	79	8
SYK	109	11
TBK1	31	1
YES1	100	2

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	13	2
Aurora B	4	0
Aurora C	6	0
BRSK2	22	3
CAMK1	52	5
CAMKK alpha	47	4
CAMKK beta	19	1
CDK2-Cyclin A	35	0
CHK1	33	0
CHK2	45	0
CK1 delta	96	6
CK2	95	6
CSK	66	10
DYRK1A	64	8
DYRK2	70	0
DYRK3	44	1
EF2K	83	4
EPH-A2	73	8
ERK1	72	3
ERK2	73	9
ERK8	18	1
FGF-R1	13	1
GSK3 beta	22	0
HIPK2	74	2
HIPK3	100	5
IKK beta	69	2
IKK epsilon	3	8
IRR	65	7
JNK1	78	3
JNK2	65	7
JNK3	102	3
Lck	41	2
MAPKAP-K2	68	1
MAPKAP-K3	76	5
MARK3	7	0
MELK	11	0
MKK1	29	1
MNK1	74	4
MNK2	31	1
MSK1	76	8
MST2	70	5
MST4	100	2
NEK2a	61	4
NEK6	91	1
NEK7	84	11
p38 alpha MAPK	95	7
p38 beta MAPK	45	4
p38 delta MAPK	74	9
p38 gamma MAPK	79	0
PAK4	26	0
PAK5	40	7
PAK6	60	0
PDK1	7	0
PHK	76	3
PIM1	63	3
PIM2	71	2
PIM3	53	4
PKA	58	3
PKB alpha	57	1
PKB beta	79	0
PKC alpha	67	0
PKC zeta	79	8
PKD1	46	10
PLK1	69	1
PRAK	66	9
PRK2	42	0
ROCK 2	56	5
RSK1	39	6
RSK2	41	6
S6K1	61	5
SGK1	45	2
SmMLCK	94	4
Src	40	2
SRPK1	69	2
SYK	62	3
TBK1	5	0
YES1	62	8