Inhibitor | Ischemin

Compound name	Brutto	MW	CAS	PubChem CID	Action	Reference	Reference
Ischemin	C₁₅H₁₇N₃O₄S	335.38			p53 CBP	Jagat C. Borah (2011) Chemistry & Biology, 18 4 531-541

Screening Results Chart

Screen Conc: 100.00µM
Kinase	% Activity Remaining Sort descending	Standard Deviation
GSK3 beta	31	3
TAK1	31	5
Aurora A	32	5
PKB beta	37	7
Src	40	2
HIPK2	42	14
NUAK1	44	7
PIM3	45	7
CAMK1	45	1
RIPK2	46	4
BRSK2	46	5
EPH-B3	48	3
CK2	51	0
YES1	52	8
SGK1	52	5
PKC gamma	55	9
PKD1	55	11
p38 alpha MAPK	58	2
MLK1	58	12
p38 beta MAPK	58	5
PIM2	58	0
SRPK1	59	4
FGF-R1	59	6
VEGFR1	62	0
MAPKAP-K3	62	7
PIM1	62	2
MINK1	62	7
TrkA	65	4
ERK8	65	8
DYRK3	65	4
MST4	67	0
PAK4	70	6
PRAK	70	8
JAK2	71	4
AMPK	71	2
TESK1	73	2
HIPK3	74	8
BRSK1	76	1
DYRK2	78	1
PLK1	79	8
RSK2	80	1
GCK	80	0
PKC alpha	81	4
MST2	81	6
MARK4	81	7
DAPK1	82	3
MLK3	83	7
MSK1	84	8
PHK	86	4
MELK	87	9
PAK5	87	9
MEKK1	88	16
EPH-A2	89	6
PDK1	90	1
TTK	90	4
PKA	90	2
ABL	92	1
EF2K	92	7
EPH-A4	92	5
Aurora B	93	3
CDK2-Cyclin A	94	8
EIF2AK3	94	1
HIPK1	94	6
TTBK1	94	13
IKK epsilon	94	1
TBK1	94	1
PAK6	96	12
EPH-B2	96	9
MARK3	96	9
PKC zeta	97	6
OSR1	97	4
EPH-B1	97	7
IKK beta	97	12
SmMLCK	97	7
MARK2	98	2
ERK1	98	8
RSK1	99	2
MNK1	99	5
MARK1	99	1
CAMKK beta	99	2
HER4	99	7
JNK3	100	9
CHK2	100	1
MNK2	100	3
BRK	100	4
PAK2	100	4
CLK2	101	28
BTK	102	8
S6K1	102	1
IRR	103	13
SYK	103	8
ZAP70	103	3
TIE2	103	1
MKK1	103	8
IRAK1	104	3
ROCK 2	105	0
TSSK1	107	2
STK33	107	14
MAPKAP-K2	107	8
p38 gamma MAPK	108	3
CK1 delta	108	24
TLK1	108	0
IRAK4	108	20
PKB alpha	108	10
IGF-1R	109	2
p38 delta MAPK	109	8
TAO1	109	3
MKK2	109	3
MPSK1	111	5
Lck	112	1
JNK2	112	2
DYRK1A	113	7
MKK6	113	8
JNK1	113	0
NEK2a	118	6
EPH-B4	123	8
LKB1	126	1
PRK2	126	6
CSK	132	11
ERK2	134	0
IR	141	8
NEK6	146	63
ASK1	151	9
CHK1	196	6