Inhibitor | ETP 46464  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	93	8
AMPK	91	4
ASK1	117	3
Aurora A	101	4
Aurora B	93	5
BRK	96	10
BRSK1	97	2
BRSK2	89	8
BTK	90	12
CAMK1	73	1
CAMKK beta	69	4
CDK2-Cyclin A	90	4
CHK1	81	5
CHK2	95	14
CK1 delta	92	7
CK2	97	1
CLK2	75	1
CSK	75	0
DAPK1	84	2
DYRK1A	89	4
DYRK2	73	14
DYRK3	57	1
EF2K	99	1
EIF2AK3	101	1
EPH-A2	69	14
EPH-A4	89	1
EPH-B1	93	2
EPH-B2	93	18
EPH-B3	116	2
EPH-B4	102	9
ERK1	85	1
ERK2	83	7
ERK8	73	1
FGF-R1	98	18
GCK	22	3
GSK3 beta	74	9
HER4	110	18
HIPK1	94	12
HIPK2	99	2
HIPK3	96	6
IGF-1R	89	12
IKK beta	86	6
IKK epsilon	111	4
IR	96	7
IRAK1	79	1
IRAK4	90	3
IRR	74	3
JAK2	26	4
JNK1	106	9
JNK2	97	21
JNK3	87	1
Lck	78	7
LKB1	87	5
MAPKAP-K2	115	18
MAPKAP-K3	88	19
MARK1	96	9
MARK2	101	5
MARK3	93	4
MARK4	100	16
MEKK1	69	12
MELK	49	12
MINK1	72	6
MKK1	78	6
MKK2	87	3
MKK6	101	3
MLK1	91	7
MLK3	81	3
MNK1	89	1
MNK2	94	2
MPSK1	87	3
MSK1	74	5
MST2	64	9
MST4	93	6
NEK2a	108	3
NEK6	83	2
NUAK1	32	1
OSR1	102	10
p38 alpha MAPK	93	7
p38 beta MAPK	89	6
p38 delta MAPK	96	9
p38 gamma MAPK	88	5
PAK2	95	7
PAK4	94	3
PAK5	99	9
PAK6	98	5
PDK1	93	7
PHK	97	2
PIM1	81	11
PIM2	91	3
PIM3	67	19
PKA	81	22
PKB alpha	102	2
PKB beta	105	23
PKC alpha	101	4
PKC gamma	111	0
PKC zeta	58	56
PKD1	79	5
PLK1	93	3
PRAK	82	9
PRK2	90	10
RIPK2	57	2
ROCK 2	120	19
RSK1	96	10
RSK2	89	14
S6K1	91	3
SGK1	96	4
SmMLCK	87	6
Src	83	8
SRPK1	90	7
STK33	115	25
SYK	105	7
TAK1	64	5
TAO1	91	0
TBK1	83	8
TESK1	116	8
TIE2	93	8
TLK1	84	15
TrkA	50	5
TSSK1	110	24
TTBK1	110	4
TTK	91	2
VEGFR1	87	13
YES1	92	15
ZAP70	75	4

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	103	1
AMPK	89	4
ASK1	111	1
Aurora A	108	10
Aurora B	82	6
BRK	97	11
BRSK1	86	5
BRSK2	100	11
BTK	85	3
CAMK1	103	25
CAMKK beta	59	3
CDK2-Cyclin A	85	5
CHK1	100	4
CHK2	94	3
CK1 delta	95	19
CK2	97	7
CLK2	91	7
CSK	89	9
DAPK1	88	15
DYRK1A	83	1
DYRK2	85	3
DYRK3	64	7
EF2K	109	3
EIF2AK3	97	3
EPH-A2	81	3
EPH-A4	89	0
EPH-B1	119	8
EPH-B2	95	10
EPH-B3	103	11
EPH-B4	96	1
ERK1	83	4
ERK2	95	9
ERK8	67	2
FGF-R1	93	1
GCK	11	3
GSK3 beta	89	0
HER4	97	6
HIPK1	97	6
HIPK2	114	3
HIPK3	94	1
IGF-1R	67	3
IKK beta	87	7
IKK epsilon	97	1
IR	96	3
IRAK1	56	10
IRAK4	89	4
IRR	77	3
JAK2	31	5
JNK1	109	10
JNK2	97	2
JNK3	77	8
Lck	98	9
LKB1	85	3
MAPKAP-K2	108	21
MAPKAP-K3	82	31
MARK1	114	4
MARK2	95	7
MARK3	102	3
MARK4	86	8
MEKK1	85	3
MELK	49	9
MINK1	55	5
MKK1	96	2
MKK2	75	13
MKK6	92	14
MLK1	89	4
MLK3	83	6
MNK1	90	0
MNK2	99	5
MPSK1	100	17
MSK1	53	5
MST2	49	0
MST4	83	5
NEK2a	103	11
NEK6	40	4
NUAK1	16	0
OSR1	103	15
p38 alpha MAPK	134	15
p38 beta MAPK	103	0
p38 delta MAPK	95	3
p38 gamma MAPK	100	12
PAK2	107	8
PAK4	108	38
PAK5	80	9
PAK6	110	4
PDK1	84	10
PHK	92	6
PIM1	73	3
PIM2	96	1
PIM3	55	15
PKA	92	1
PKB alpha	117	12
PKB beta	100	7
PKC alpha	94	1
PKC gamma	99	10
PKC zeta	96	22
PKD1	81	10
PLK1	87	7
PRAK	89	5
PRK2	84	8
RIPK2	38	5
ROCK 2	104	8
RSK1	73	0
RSK2	100	11
S6K1	96	2
SGK1	82	4
SmMLCK	100	1
Src	130	13
SRPK1	89	1
STK33	98	4
SYK	76	2
TAK1	78	12
TAO1	94	4
TBK1	96	8
TESK1	108	3
TIE2	95	2
TLK1	101	3
TrkA	53	30
TSSK1	103	1
TTBK1	100	11
TTK	86	5
VEGFR1	107	11
YES1	93	8
ZAP70	77	3