Inhibitor | PD 0325901-Cl (CI-1055-R)  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
PD 0325901-Cl (CI-1055-R)   C16H14O4N2F2ClI 498.65 391210-10-9 5330286 MEK1

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
ABL 103 19
AMPK 110 4
ASK1 108 4
Aurora A 112 9
Aurora B 87 8
BRK 115 4
BRSK1 97 4
BRSK2 94 8
BTK 110 19
CAMK1 96 5
CAMKK beta 92 3
CDK2-Cyclin A 110 13
CHK1 130 1
CHK2 95 7
CK1 delta 89 6
CK2 107 13
CLK2 103 14
CSK 93 5
DAPK1 96 11
DYRK1A 94 2
DYRK2 99 6
DYRK3 85 3
EF2K 83 10
EIF2AK3 96 0
EPH-A2 86 13
EPH-A4 86 5
EPH-B1 95 13
EPH-B2 64 10
EPH-B3 101 3
EPH-B4 90 5
ERK1 88 7
ERK2 90 6
ERK8 104 16
FGF-R1 140 2
GCK 90 7
GSK3 beta 70 18
HER4 112 30
HIPK1 84 6
HIPK2 93 4
HIPK3 101 7
IGF-1R 88 12
IKK beta 88 2
IKK epsilon 103 4
IR 106 41
IRAK1 84 5
IRAK4 81 4
IRR 106 0
JAK2
8
 0
JNK1 91 5
JNK2 90 9
JNK3 89 23
Lck 92 7
LKB1 113 13
MAPKAP-K2 103 1
MAPKAP-K3 90 11
MARK1 85 14
MARK2 104 12
MARK3 91 9
MARK4 112 4
MEKK1 97 10
MELK 81 10
MINK1 117 5
MKK1 18 5
MKK2 54 9
MKK6 93 6
MLK1 95 2
MLK3 83 1
MNK1 103 14
MNK2 93 14
MPSK1 85 17
MSK1 97 13
MST2 83 12
MST4 103 4
NEK2a 97 13
NEK6 95 1
NUAK1 89 5
OSR1 95 14
p38 alpha MAPK 96 6
p38 beta MAPK 99 12
p38 delta MAPK 85 1
p38 gamma MAPK 91 19
PAK2 96 24
PAK4 97 22
PAK5 104 1
PAK6 95 0
PDK1 101 15
PHK 95 8
PIM1 92 7
PIM2 104 4
PIM3 78 10
PKA 87 16
PKB alpha 107 16
PKB beta 95 7
PKC alpha 100 5
PKC gamma 91 4
PKC zeta 97 2
PKD1 89 23
PLK1 81 1
PRAK 98 7
PRK2 82 2
RIPK2 99 1
ROCK 2 84 14
RSK1 102 11
RSK2 104 14
S6K1 97 18
SGK1 69 9
SmMLCK 100 22
Src 104 5
SRPK1 80 7
STK33 87 32
SYK 111 9
TAK1 77 7
TAO1 101 8
TBK1 117 4
TIE2 97 20
TLK1 96 2
TrkA 72 6
TTK 98 2
VEGFR1 65 38
YES1 82 1
ZAP70 84 8
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ABL 98 1
AMPK 107 2
ASK1 116 2
Aurora A 108 7
Aurora B 82 3
BRK 121 6
BRSK1 112 9
BRSK2 96 5
BTK 100 6
CAMK1 91 0
CAMKK beta 94 9
CDK2-Cyclin A 109 2
CHK1 122 17
CHK2 114 11
CK1 delta 101 12
CK2 118 2
CLK2 85 11
CSK 98 4
DAPK1 90 8
DYRK1A 104 11
DYRK2 107 4
DYRK3 85 9
EF2K 93 13
EIF2AK3 105 8
EPH-A2 94 8
EPH-A4 89 1
EPH-B1 115 10
EPH-B2 74 16
EPH-B3 113 7
EPH-B4 99 14
ERK1 106 12
ERK2 100 12
ERK8 96 3
FGF-R1 83 14
GCK 77 29
GSK3 beta 88 12
HER4 87 8
HIPK1 92 18
HIPK2 104 1
HIPK3 107 13
IGF-1R 113 2
IKK beta 103 6
IKK epsilon 111 9
IR 107 24
IRAK1 89 0
IRAK4 100 4
IRR 112 33
JAK2
9
 1
JNK1 117 9
JNK2 105 8
JNK3 85 1
Lck 109 7
LKB1 108 24
MAPKAP-K2 102 3
MAPKAP-K3 89 2
MARK1 85 11
MARK2 103 5
MARK3 74 1
MARK4 127 4
MEKK1 105 3
MELK 97 8
MINK1 144 16
MKK1
2
 5
MKK2 16 3
MKK6 102 2
MLK1 108 14
MLK3 92 7
MNK1 104 2
MNK2 110 5
MPSK1 101 1
MSK1 96 4
MST2 70 1
MST4 104 10
NEK2a 102 5
NEK6 110 13
NUAK1 107 6
OSR1 93 4
p38 alpha MAPK 97 7
p38 beta MAPK 105 12
p38 delta MAPK 97 19
p38 gamma MAPK 98 3
PAK2 91 9
PAK4 65 2
PAK5 85 4
PAK6 105 5
PDK1 109 6
PHK 90 6
PIM1 73 1
PIM2 97 19
PIM3 72 6
PKA 97 8
PKB alpha 104 1
PKB beta 82 2
PKC alpha 108 3
PKC gamma 99 4
PKC zeta 104 12
PKD1 93 15
PLK1 92 12
PRAK 99 2
PRK2 83 0
RIPK2 100 3
ROCK 2 120 53
RSK1 102 4
RSK2 92 1
S6K1 81 2
SGK1 74 9
SmMLCK 98 14
Src 91 8
SRPK1 95 14
STK33 107 9
SYK 74 20
TAK1 82 8
TAO1 109 6
TBK1 101 1
TIE2 96 14
TLK1 104 10
TrkA 75 19
TTK 121 9
VEGFR1 39 10
YES1 86 2
ZAP70 100 14