Inhibitor | CP-690550 (Tasocitinib)  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
ABL	116	10
AMPK	95	5
ASK1	130	11
Aurora A	119	16
Aurora B	92	8
BRK	92	7
BRSK1	92	7
BRSK2	101	3
BTK	94	11
CAMK1	111	2
CAMKK beta	116	10
CDK2-Cyclin A	116	37
CHK1	88	1
CHK2	95	9
CK1 delta	109	9
CK2	97	7
CLK2	108	1
CSK	78	3
DAPK1	123	11
DYRK1A	92	7
DYRK2	103	5
DYRK3	116	2
EF2K	100	2
EIF2AK3	97	9
EPH-A2	114	19
EPH-A4	109	3
EPH-B1	93	4
EPH-B2	121	12
EPH-B3	85	5
EPH-B4	120	4
ERK1	97	4
ERK2	97	10
ERK8	121	6
FGF-R1	85	3
GCK	109	7
GSK3 beta	108	9
HER4	121	19
HIPK1	112	4
HIPK2	117	6
HIPK3	108	3
IGF-1R	104	11
IKK beta	105	2
IKK epsilon	87	8
IR	105	9
IRAK1	106	3
IRAK4	87	0
IRR	103	5
JAK2	4	0
JNK1	80	3
JNK2	94	4
JNK3	119	12
Lck	73	9
LKB1	101	9
MAPKAP-K2	82	7
MAPKAP-K3	91	4
MARK1	82	10
MARK2	98	1
MARK3	94	16
MARK4	93	2
MEKK1	97	7
MELK	115	12
MINK1	96	7
MKK1	105	6
MKK2	110	3
MKK6	97	8
MLK1	86	5
MLK3	83	12
MNK1	100	11
MNK2	97	2
MPSK1	94	10
MSK1	83	10
MST2	79	7
MST4	87	8
NEK2a	102	16
NEK6	87	3
NUAK1	74	5
OSR1	112	9
p38 alpha MAPK	100	1
p38 beta MAPK	106	12
p38 delta MAPK	101	7
p38 gamma MAPK	115	6
PAK2	99	2
PAK4	104	10
PAK5	86	7
PAK6	100	3
PDK1	107	14
PHK	96	2
PIM1	112	5
PIM2	102	5
PIM3	124	12
PKA	94	4
PKB alpha	115	1
PKB beta	85	9
PKC alpha	96	0
PKC gamma	100	21
PKC zeta	99	11
PKD1	92	4
PLK1	128	7
PRAK	113	10
PRK2	50	2
RIPK2	91	9
ROCK 2	95	15
RSK1	96	6
RSK2	91	3
S6K1	88	0
SGK1	92	2
SmMLCK	105	3
Src	92	5
SRPK1	84	6
STK33	98	4
SYK	131	7
TAK1	115	7
TAO1	104	12
TBK1	99	6
TIE2	99	1
TLK1	100	3
TrkA	106	13
TTK	99	3
VEGFR1	99	5
YES1	104	3
ZAP70	133	0

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	103	13
AMPK	83	1
ASK1	105	7
Aurora A	93	8
Aurora B	69	6
BRK	80	18
BRSK1	73	2
BRSK2	82	5
BTK	96	6
CAMK1	93	1
CAMKK beta	139	15
CDK2-Cyclin A	69	4
CHK1	86	13
CHK2	106	7
CK1 delta	105	4
CK2	92	1
CLK2	106	10
CSK	84	7
DAPK1	145	5
DYRK1A	102	1
DYRK2	99	14
DYRK3	110	18
EF2K	103	1
EIF2AK3	114	8
EPH-A2	106	6
EPH-A4	121	2
EPH-B1	93	4
EPH-B2	91	10
EPH-B3	103	8
EPH-B4	131	46
ERK1	108	5
ERK2	99	17
ERK8	121	1
FGF-R1	42	4
GCK	87	0
GSK3 beta	110	2
HER4	116	8
HIPK1	90	4
HIPK2	128	21
HIPK3	109	14
IGF-1R	109	9
IKK beta	126	3
IKK epsilon	90	7
IR	87	8
IRAK1	111	4
IRAK4	80	1
IRR	102	3
JAK2	3	1
JNK1	81	5
JNK2	88	9
JNK3	107	10
Lck	30	0
LKB1	95	5
MAPKAP-K2	91	11
MAPKAP-K3	118	7
MARK1	63	1
MARK2	85	4
MARK3	33	4
MARK4	86	1
MEKK1	83	80
MELK	74	5
MINK1	90	9
MKK1	67	6
MKK2	112	20
MKK6	89	2
MLK1	90	8
MLK3	75	1
MNK1	115	0
MNK2	64	10
MPSK1	83	14
MSK1	76	15
MST2	64	12
MST4	109	0
NEK2a	107	32
NEK6	90	5
NUAK1	30	2
OSR1	94	12
p38 alpha MAPK	103	4
p38 beta MAPK	115	3
p38 delta MAPK	108	17
p38 gamma MAPK	130	9
PAK2	114	2
PAK4	116	16
PAK5	94	4
PAK6	116	10
PDK1	123	3
PHK	85	11
PIM1	101	8
PIM2	121	21
PIM3	114	9
PKA	89	1
PKB alpha	125	4
PKB beta	92	6
PKC alpha	71	0
PKC gamma	106	20
PKC zeta	102	5
PKD1	106	27
PLK1	121	18
PRAK	123	7
PRK2	22	0
RIPK2	92	3
ROCK 2	46	9
RSK1	76	23
RSK2	86	2
S6K1	77	16
SGK1	106	19
SmMLCK	104	3
Src	90	7
SRPK1	89	8
STK33	103	19
SYK	152	16
TAK1	113	34
TAO1	103	4
TBK1	83	19
TIE2	106	19
TLK1	104	8
TrkA	87	11
TTK	115	7
VEGFR1	58	10
YES1	65	4
ZAP70	125	3