Inhibitor | MRT67307  

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
MARK3	1	1
MLK3	8	0
MARK1	9	2
MARK2	10	1
TBK1	10	2
NUAK1	11	1
JAK2	14	2
MLK1	16	3
CLK2	21	2
CAMKK beta	21	0
IKK epsilon	23	10
MELK	26	3
AMPK	27	3
PHK	28	2
Aurora A	29	1
MARK4	29	5
ERK8	34	2
RSK1	34	2
PDK1	42	2
CDK2-Cyclin A	47	5
TrkA	47	2
PKD1	49	0
MNK2	50	15
STK33	52	9
Aurora B	54	5
RSK2	56	2
TAK1	57	6
CHK1	57	3
FGF-R1	63	5
GCK	64	2
PRK2	66	6
CK1 delta	66	11
Lck	67	2
MSK1	68	2
Src	70	2
YES1	71	7
TAO1	71	9
DAPK1	72	7
CHK2	72	0
TTK	74	3
VEGFR1	74	11
MKK2	75	10
BRSK2	75	5
BTK	77	3
EPH-B2	78	17
IRAK1	79	4
PAK4	79	2
TIE2	81	4
ROCK 2	81	1
BRSK1	82	5
IRAK4	83	5
MKK1	84	1
PAK6	84	4
p38 gamma MAPK	85	8
PIM2	85	1
CK2	86	9
EIF2AK3	86	11
PAK5	88	1
ASK1	88	1
p38 delta MAPK	90	2
NEK6	90	9
PAK2	92	2
PKB alpha	93	7
PKC alpha	93	7
SYK	93	9
OSR1	94	5
SGK1	94	6
MST4	94	9
HIPK1	94	11
ZAP70	94	12
HIPK2	95	15
HER4	95	1
PKC zeta	95	10
MNK1	96	3
GSK3 beta	96	7
NEK2a	97	11
ABL	97	6
JNK3	97	11
PLK1	98	10
EPH-A2	98	5
PKC gamma	98	1
PKA	100	12
IR	100	15
DYRK2	101	10
DYRK3	101	7
EPH-B3	101	10
S6K1	101	1
CAMK1	101	13
SRPK1	101	10
SmMLCK	103	3
MINK1	103	7
MAPKAP-K3	104	10
MPSK1	104	10
IGF-1R	105	10
DYRK1A	106	1
JNK2	106	8
p38 alpha MAPK	107	0
HIPK3	108	3
TLK1	108	15
EPH-B1	108	11
PKB beta	108	1
BRK	110	2
ERK2	110	4
EF2K	110	2
PIM3	111	2
RIPK2	112	8
ERK1	112	11
CSK	112	1
MKK6	113	3
EPH-A4	114	11
MAPKAP-K2	114	9
p38 beta MAPK	114	5
JNK1	115	6
EPH-B4	117	7
LKB1	118	15
IRR	118	7
PIM1	120	12
IKK beta	122	6
PRAK	122	13
MST2	129	1
MEKK1	137	2

Screen Conc: 0.10µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
TBK1	12	1
MARK3	15	12
MARK1	16	4
MARK2	27	4
MARK4	33	2
IKK epsilon	34	13
MLK1	40	9
JAK2	41	2
MELK	43	10
NUAK1	47	4
MLK3	54	1
CAMKK beta	58	3
CLK2	63	3
AMPK	64	1
RSK2	71	19
RSK1	73	1
PDK1	75	4
GCK	77	6
PHK	78	3
TAO1	78	7
PKC alpha	79	0
STK33	80	11
Aurora B	80	11
MNK2	80	14
Lck	80	1
MAPKAP-K3	80	7
SGK1	81	1
ERK8	81	9
PKD1	82	3
OSR1	83	8
FGF-R1	83	12
TrkA	84	5
DAPK1	84	4
SRPK1	86	7
CDK2-Cyclin A	86	10
CK2	86	12
SmMLCK	87	8
VEGFR1	87	9
PRK2	87	1
Aurora A	87	4
PAK6	87	14
MST4	87	4
BRSK2	88	1
PKC gamma	88	14
p38 gamma MAPK	88	5
p38 delta MAPK	88	6
EPH-B2	88	13
Src	88	0
BTK	89	3
PLK1	89	1
MNK1	89	2
HER4	90	3
IGF-1R	90	7
PKA	90	4
PKC zeta	90	1
TLK1	90	8
PKB alpha	90	3
ROCK 2	91	11
HIPK3	91	6
DYRK3	91	16
ABL	92	5
EIF2AK3	92	1
ZAP70	92	3
DYRK2	92	14
MKK1	92	13
JNK1	93	4
CHK1	93	10
PIM2	94	5
NEK6	94	1
TTK	94	11
HIPK2	95	7
TIE2	95	9
GSK3 beta	95	15
IRAK4	95	5
EPH-A2	95	1
PAK5	95	0
HIPK1	96	11
TAK1	96	7
IRAK1	96	14
BRK	96	2
IR	97	9
JNK2	97	14
CSK	98	13
EF2K	98	4
MSK1	98	3
PKB beta	99	3
BRSK1	99	3
CK1 delta	99	8
DYRK1A	99	2
p38 alpha MAPK	100	6
PAK4	100	1
S6K1	101	11
PAK2	101	12
EPH-B4	101	11
p38 beta MAPK	103	4
EPH-A4	103	1
PRAK	104	9
PIM3	104	8
CAMK1	104	13
MKK6	105	1
ERK1	105	12
ASK1	105	3
CHK2	105	7
MKK2	106	0
MAPKAP-K2	106	5
IRR	107	1
EPH-B1	107	4
NEK2a	107	11
SYK	109	2
RIPK2	109	7
LKB1	109	4
JNK3	110	4
EPH-B3	110	13
MST2	110	2
ERK2	111	5
YES1	113	9
PIM1	114	14
MEKK1	115	6
IKK beta	115	2
MPSK1	117	24
MINK1	123	15