Inhibitor |
Sodium salicylate
Screening Results Tables
Screen Conc:
1.00µM
Kinase |
% Activity Remaining |
Standard Deviation |
ABL
|
88
|
10
|
AMPK
|
102
|
18
|
ASK1
|
93
|
2
|
Aurora A
|
77
|
1
|
Aurora B
|
75
|
11
|
BRK
|
91
|
9
|
BRSK1
|
86
|
23
|
BRSK2
|
86
|
4
|
BTK
|
74
|
8
|
CAMK1
|
79
|
1
|
CAMKK beta
|
75
|
3
|
CDK2-Cyclin A
|
102
|
18
|
CHK1
|
102
|
5
|
CHK2
|
81
|
5
|
CK1 delta
|
92
|
13
|
CK2
|
11
|
1
|
CLK2
|
84
|
11
|
CSK
|
109
|
8
|
DAPK1
|
47
|
5
|
DYRK1A
|
47
|
6
|
DYRK2
|
87
|
14
|
DYRK3
|
75
|
7
|
EF2K
|
91
|
0
|
EIF2AK3
|
89
|
15
|
EPH-A2
|
99
|
4
|
EPH-A4
|
97
|
13
|
EPH-B1
|
96
|
1
|
EPH-B2
|
92
|
0
|
EPH-B3
|
83
|
7
|
EPH-B4
|
114
|
13
|
ERK1
|
88
|
15
|
ERK2
|
82
|
1
|
ERK8
|
69
|
0
|
FGF-R1
|
85
|
20
|
GCK
|
81
|
3
|
GSK3 beta
|
91
|
3
|
HER4
|
83
|
1
|
HIPK1
|
87
|
4
|
HIPK2
|
69
|
1
|
HIPK3
|
112
|
8
|
IGF-1R
|
91
|
1
|
IKK beta
|
88
|
1
|
IKK epsilon
|
109
|
4
|
IR
|
91
|
13
|
IRAK1
|
89
|
6
|
IRAK4
|
92
|
5
|
IRR
|
84
|
3
|
JAK2
|
101
|
16
|
JNK1
|
102
|
4
|
JNK2
|
103
|
2
|
JNK3
|
82
|
31
|
Lck
|
105
|
3
|
LKB1
|
81
|
1
|
MAPKAP-K2
|
101
|
16
|
MAPKAP-K3
|
71
|
3
|
MARK1
|
83
|
1
|
MARK2
|
86
|
12
|
MARK3
|
85
|
4
|
MARK4
|
89
|
0
|
MEKK1
|
102
|
18
|
MELK
|
94
|
9
|
MINK1
|
103
|
1
|
MKK1
|
81
|
2
|
MKK2
|
77
|
6
|
MKK6
|
113
|
6
|
MLK1
|
76
|
7
|
MLK3
|
118
|
22
|
MNK1
|
83
|
5
|
MNK2
|
95
|
5
|
MPSK1
|
98
|
16
|
MSK1
|
91
|
1
|
MST2
|
99
|
7
|
MST4
|
87
|
13
|
NEK2a
|
94
|
5
|
NEK6
|
89
|
7
|
NUAK1
|
85
|
2
|
OSR1
|
85
|
10
|
p38 alpha MAPK
|
100
|
22
|
p38 beta MAPK
|
91
|
5
|
p38 delta MAPK
|
94
|
12
|
p38 gamma MAPK
|
82
|
2
|
PAK2
|
87
|
2
|
PAK4
|
73
|
8
|
PAK5
|
80
|
7
|
PAK6
|
84
|
8
|
PDK1
|
88
|
10
|
PHK
|
82
|
5
|
PIM1
|
35
|
2
|
PIM2
|
67
|
1
|
PIM3
|
13
|
5
|
PKA
|
94
|
3
|
PKB alpha
|
97
|
4
|
PKB beta
|
75
|
3
|
PKC alpha
|
101
|
0
|
PKC gamma
|
95
|
16
|
PKC zeta
|
84
|
6
|
PKD1
|
97
|
3
|
PLK1
|
107
|
10
|
PRAK
|
87
|
6
|
PRK2
|
93
|
12
|
RIPK2
|
73
|
4
|
ROCK 2
|
95
|
5
|
RSK1
|
93
|
2
|
RSK2
|
86
|
8
|
S6K1
|
95
|
5
|
SGK1
|
82
|
2
|
SmMLCK
|
96
|
6
|
Src
|
81
|
2
|
SRPK1
|
61
|
1
|
STK33
|
95
|
5
|
SYK
|
80
|
25
|
TAK1
|
137
|
23
|
TAO1
|
86
|
9
|
TBK1
|
85
|
5
|
TIE2
|
97
|
2
|
TLK1
|
102
|
1
|
TrkA
|
82
|
14
|
TTK
|
82
|
8
|
VEGFR1
|
65
|
3
|
YES1
|
79
|
1
|
ZAP70
|
103
|
11
|
Screen Conc:
10.00µM
Kinase |
% Activity Remaining |
Standard Deviation |
ABL
|
95
|
5
|
AMPK
|
88
|
4
|
ASK1
|
107
|
12
|
Aurora A
|
18
|
3
|
Aurora B
|
89
|
34
|
BRK
|
64
|
15
|
BRSK1
|
70
|
3
|
BRSK2
|
50
|
7
|
BTK
|
19
|
3
|
CAMK1
|
56
|
1
|
CAMKK beta
|
30
|
17
|
CDK2-Cyclin A
|
89
|
9
|
CHK1
|
130
|
2
|
CHK2
|
36
|
6
|
CK1 delta
|
35
|
5
|
CK2
|
5
|
2
|
CLK2
|
79
|
18
|
CSK
|
62
|
5
|
DAPK1
|
17
|
1
|
DYRK1A
|
40
|
10
|
DYRK2
|
37
|
4
|
DYRK3
|
30
|
3
|
EF2K
|
52
|
1
|
EIF2AK3
|
44
|
6
|
EPH-A2
|
66
|
3
|
EPH-A4
|
89
|
7
|
EPH-B1
|
85
|
13
|
EPH-B2
|
58
|
3
|
EPH-B3
|
57
|
18
|
EPH-B4
|
142
|
9
|
ERK1
|
99
|
20
|
ERK2
|
89
|
0
|
ERK8
|
36
|
6
|
FGF-R1
|
25
|
6
|
GCK
|
64
|
11
|
GSK3 beta
|
48
|
2
|
HER4
|
33
|
2
|
HIPK1
|
59
|
4
|
HIPK2
|
39
|
11
|
HIPK3
|
93
|
10
|
IGF-1R
|
67
|
7
|
IKK beta
|
93
|
25
|
IKK epsilon
|
111
|
2
|
IR
|
38
|
6
|
IRAK1
|
43
|
4
|
IRAK4
|
61
|
5
|
IRR
|
68
|
23
|
JAK2
|
47
|
5
|
JNK1
|
136
|
2
|
JNK2
|
109
|
1
|
JNK3
|
100
|
8
|
Lck
|
81
|
19
|
LKB1
|
64
|
4
|
MAPKAP-K2
|
97
|
16
|
MAPKAP-K3
|
55
|
1
|
MARK1
|
51
|
10
|
MARK2
|
75
|
3
|
MARK3
|
71
|
9
|
MARK4
|
65
|
8
|
MEKK1
|
147
|
13
|
MELK
|
123
|
4
|
MINK1
|
107
|
16
|
MKK1
|
48
|
16
|
MKK2
|
88
|
0
|
MKK6
|
143
|
4
|
MLK1
|
50
|
6
|
MLK3
|
103
|
11
|
MNK1
|
44
|
3
|
MNK2
|
68
|
4
|
MPSK1
|
98
|
6
|
MSK1
|
57
|
2
|
MST2
|
90
|
18
|
MST4
|
82
|
8
|
NEK2a
|
64
|
4
|
NEK6
|
69
|
3
|
NUAK1
|
50
|
0
|
OSR1
|
55
|
18
|
p38 alpha MAPK
|
95
|
6
|
p38 beta MAPK
|
101
|
24
|
p38 delta MAPK
|
73
|
1
|
p38 gamma MAPK
|
36
|
0
|
PAK2
|
64
|
14
|
PAK4
|
38
|
5
|
PAK5
|
55
|
3
|
PAK6
|
47
|
6
|
PDK1
|
86
|
7
|
PHK
|
59
|
8
|
PIM1
|
9
|
1
|
PIM2
|
35
|
0
|
PIM3
|
12
|
6
|
PKA
|
101
|
25
|
PKB alpha
|
66
|
4
|
PKB beta
|
40
|
2
|
PKC alpha
|
92
|
4
|
PKC gamma
|
68
|
5
|
PKC zeta
|
110
|
2
|
PKD1
|
69
|
10
|
PLK1
|
108
|
7
|
PRAK
|
49
|
5
|
PRK2
|
77
|
6
|
RIPK2
|
57
|
11
|
ROCK 2
|
86
|
7
|
RSK1
|
89
|
19
|
RSK2
|
56
|
11
|
S6K1
|
59
|
3
|
SGK1
|
69
|
4
|
SmMLCK
|
64
|
3
|
Src
|
50
|
2
|
SRPK1
|
12
|
1
|
STK33
|
80
|
9
|
SYK
|
48
|
2
|
TAK1
|
143
|
20
|
TAO1
|
66
|
4
|
TBK1
|
60
|
6
|
TIE2
|
93
|
0
|
TLK1
|
131
|
24
|
TrkA
|
42
|
6
|
TTK
|
49
|
15
|
VEGFR1
|
19
|
0
|
YES1
|
59
|
27
|
ZAP70
|
124
|
2
|