Inhibitor | MLN9708  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
MLN9708   C20H23BCl2N2O9 517.12 1201902-80-8 49867936 Proteasome Kupperman. E. (2010) Cancer Research 70 1970-1980

Screening Results Chart

Screening Results Tables

Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
GCK 44 48
PHK 44 3
IR 58 3
EPH-B3 62 16
VEGFR1 64 3
SYK 66 7
PAK6 68 1
EPH-A4 69 7
FGF-R1 69 7
CSK 69 10
p38 beta MAPK 70 2
MARK3 72 18
HER4 72 6
MINK1 73 5
MLK1 75 0
EPH-B1 75 8
Aurora B 75 3
ROCK 2 76 0
PAK4 77 6
SGK1 78 11
NUAK1 78 14
IRAK4 79 3
CLK2 79 6
MNK1 79 2
CAMK1 80 2
MELK 80 11
RSK1 80 8
MNK2 80 14
PDK1 80 2
MARK2 81 5
TBK1 81 1
ASK1 81 2
CK1 delta 81 3
Lck 81 1
MARK1 81 9
PKB beta 82 1
CK2 82 2
PKD1 82 0
NEK6 82 2
AMPK 82 2
YES1 82 2
EF2K 83 10
PKB alpha 83 1
ZAP70 84 11
JNK1 85 1
CAMKK beta 86 4
MARK4 86 2
ERK2 86 0
PRK2 86 2
CDK2-Cyclin A 86 5
Src 86 0
JNK2 87 8
IGF-1R 87 15
PIM1 88 4
DAPK1 88 12
p38 alpha MAPK 88 1
HIPK2 88 7
GSK3 beta 88 9
DYRK1A 88 10
MAPKAP-K2 88 2
CHK2 89 9
BTK 90 11
BRSK1 90 8
BRSK2 90 1
SRPK1 90 1
JNK3 91 3
RIPK2 91 10
EPH-B4 91 5
IKK epsilon 91 6
PRAK 92 9
MKK6 92 6
MEKK1 92 1
PIM3 92 11
PAK2 92 6
MKK1 92 9
TTK 93 10
MKK2 94 6
S6K1 94 9
PIM2 94 12
DYRK2 94 11
NEK2a 94 12
PAK5 94 19
RSK2 94 2
TrkA 95 0
PKA 95 12
PKC zeta 95 4
EPH-B2 95 8
BRK 96 6
PLK1 97 4
MSK1 97 22
DYRK3 97 1
IKK beta 97 9
TIE2 98 0
EPH-A2 98 6
p38 delta MAPK 98 6
STK33 98 13
MLK3 99 6
ERK8 100 5
MST2 100 3
ABL 101 3
MPSK1 102 17
MAPKAP-K3 102 0
SmMLCK 103 9
IRR 104 10
JAK2 104 13
p38 gamma MAPK 104 25
Aurora A 105 9
ERK1 106 5
CHK1 107 2
HIPK1 111 10
TAO1 113 21
PKC alpha 113 11
PKC gamma 114 5
HIPK3 118 5
MST4 122 6
LKB1 124 7
TAK1 127 18