Inhibitor | MLN9708  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
MLN9708   C20H23BCl2N2O9 517.12 1201902-80-8 49867936 Proteasome Kupperman. E. (2010) Cancer Research 70 1970-1980

Screening Results Chart

Screening Results Tables

Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ABL 101 3
AMPK 82 2
ASK1 81 2
Aurora A 105 9
Aurora B 75 3
BRK 96 6
BRSK1 90 8
BRSK2 90 1
BTK 90 11
CAMK1 80 2
CAMKK beta 86 4
CDK2-Cyclin A 86 5
CHK1 107 2
CHK2 89 9
CK1 delta 81 3
CK2 82 2
CLK2 79 6
CSK 69 10
DAPK1 88 12
DYRK1A 88 10
DYRK2 94 11
DYRK3 97 1
EF2K 83 10
EPH-A2 98 6
EPH-A4 69 7
EPH-B1 75 8
EPH-B2 95 8
EPH-B3 62 16
EPH-B4 91 5
ERK1 106 5
ERK2 86 0
ERK8 100 5
FGF-R1 69 7
GCK 44 48
GSK3 beta 88 9
HER4 72 6
HIPK1 111 10
HIPK2 88 7
HIPK3 118 5
IGF-1R 87 15
IKK beta 97 9
IKK epsilon 91 6
IR 58 3
IRAK4 79 3
IRR 104 10
JAK2 104 13
JNK1 85 1
JNK2 87 8
JNK3 91 3
Lck 81 1
LKB1 124 7
MAPKAP-K2 88 2
MAPKAP-K3 102 0
MARK1 81 9
MARK2 81 5
MARK3 72 18
MARK4 86 2
MEKK1 92 1
MELK 80 11
MINK1 73 5
MKK1 92 9
MKK2 94 6
MKK6 92 6
MLK1 75 0
MLK3 99 6
MNK1 79 2
MNK2 80 14
MPSK1 102 17
MSK1 97 22
MST2 100 3
MST4 122 6
NEK2a 94 12
NEK6 82 2
NUAK1 78 14
p38 alpha MAPK 88 1
p38 beta MAPK 70 2
p38 delta MAPK 98 6
p38 gamma MAPK 104 25
PAK2 92 6
PAK4 77 6
PAK5 94 19
PAK6 68 1
PDK1 80 2
PHK 44 3
PIM1 88 4
PIM2 94 12
PIM3 92 11
PKA 95 12
PKB alpha 83 1
PKB beta 82 1
PKC alpha 113 11
PKC gamma 114 5
PKC zeta 95 4
PKD1 82 0
PLK1 97 4
PRAK 92 9
PRK2 86 2
RIPK2 91 10
ROCK 2 76 0
RSK1 80 8
RSK2 94 2
S6K1 94 9
SGK1 78 11
SmMLCK 103 9
Src 86 0
SRPK1 90 1
STK33 98 13
SYK 66 7
TAK1 127 18
TAO1 113 21
TBK1 81 1
TIE2 98 0
TrkA 95 0
TTK 93 10
VEGFR1 64 3
YES1 82 2
ZAP70 84 11