Inhibitor | IKK-2 Inhibitor VIII  

Screen Conc: 1.00µM

Kinase Sort ascending	% Activity Remaining	Standard Deviation
YES1	79	0
VEGFR1	101	11
TTK	89	10
TrkA	68	1
TBK1	80	9
TAO1	77	1
TAK1	73	3
SYK	88	12
SRPK1	92	8
Src	89	8
SmMLCK	70	1
SGK1	96	4
S6K1	88	8
RSK2	39	6
RSK1	45	6
ROCK 2	88	13
RIPK2	80	13
PRK2	94	7
PRAK	90	12
PLK1	83	5
PKD1	106	9
PKC zeta	88	6
PKC alpha	117	7
PKB beta	85	2
PKB alpha	81	9
PKA	83	1
PIM3	56	3
PIM2	34	2
PIM1	63	7
PHK	77	4
PDK1	90	1
PAK6	89	9
PAK5	84	5
PAK4	112	13
PAK2	83	12
p38 gamma MAPK	94	3
p38 delta MAPK	85	12
p38 beta MAPK	88	11
p38 alpha MAPK	102	15
NUAK1	53	3
NEK6	99	7
NEK2a	85	5
MST4	113	0
MST2	83	7
MSK1	105	5
MNK2	113	3
MNK1	101	3
MLK3	87	12
MLK1	73	0
MKK6	76	4
MKK2	107	5
MKK1	117	2
MINK1	66	11
MELK	88	1
MEKK1	62	1
MARK4	115	6
MARK3	118	10
MARK2	89	1
MARK1	88	11
MAPKAP-K3	87	12
MAPKAP-K2	115	1
LKB1	78	8
Lck	82	8
JNK3	73	6
JNK2	83	4
JNK1	110	1
JAK2	27	5
IRR	117	7
IRAK4	124	2
IR	51	13
IKK epsilon	87	1
IKK beta	6	0
IGF-1R	86	12
HIPK3	129	2
HIPK2	80	5
HIPK1	113	8
HER4	71	1
GSK3 beta	80	3
GCK	77	3
FGF-R1	97	0
ERK8	59	2
ERK2	101	4
ERK1	85	10
EPH-B4	90	11
EPH-B3	94	15
EPH-B2	119	12
EPH-B1	96	9
EPH-A4	107	14
EPH-A2	99	13
EF2K	90	3
DYRK3	84	1
DYRK2	91	3
DYRK1A	99	4
DAPK1	68	8
CSK	83	11
CLK2	43	10
CK2	91	2
CK1 delta	86	6
CHK2	60	4
CHK1	95	14
CDK2-Cyclin A	32	1
CAMKK beta	106	1
CAMK1	85	6
BTK	122	13
BRSK2	92	11
BRSK1	107	5
Aurora B	67	12
Aurora A	111	1
ASK1	102	14
AMPK	85	2

Screen Conc: 10.00µM

Kinase Sort ascending	% Activity Remaining	Standard Deviation
YES1	38	13
VEGFR1	53	3
TTK	66	3
TrkA	20	8
TBK1	86	9
TAO1	57	6
TAK1	39	2
SYK	81	8
SRPK1	101	5
Src	68	3
SmMLCK	25	1
SGK1	69	2
S6K1	53	9
RSK2	11	1
RSK1	6	0
ROCK 2	61	4
RIPK2	57	3
PRK2	53	2
PRAK	88	8
PLK1	87	14
PKD1	45	4
PKC zeta	76	2
PKC alpha	55	3
PKB beta	62	5
PKB alpha	63	1
PKA	95	7
PIM3	27	5
PIM2	12	2
PIM1	18	3
PHK	59	5
PDK1	94	8
PAK6	83	2
PAK5	75	8
PAK4	69	2
PAK2	78	8
p38 gamma MAPK	72	6
p38 delta MAPK	68	8
p38 beta MAPK	71	4
p38 alpha MAPK	91	7
NUAK1	24	3
NEK6	101	5
NEK2a	94	6
MST4	102	5
MST2	34	1
MSK1	55	7
MNK2	89	4
MNK1	90	13
MLK3	44	4
MLK1	66	5
MKK6	83	13
MKK2	77	8
MKK1	51	4
MINK1	52	2
MELK	29	4
MEKK1	50	11
MARK4	102	5
MARK3	82	6
MARK2	96	11
MARK1	95	5
MAPKAP-K3	85	9
MAPKAP-K2	95	4
LKB1	65	3
Lck	33	1
JNK3	68	11
JNK2	71	3
JNK1	80	4
JAK2	4	2
IRR	61	3
IRAK4	70	6
IR	33	7
IKK epsilon	96	8
IKK beta	4	2
IGF-1R	35	7
HIPK3	79	5
HIPK2	59	2
HIPK1	62	2
HER4	67	12
GSK3 beta	73	8
GCK	41	4
FGF-R1	72	8
ERK8	9	0
ERK2	76	1
ERK1	80	4
EPH-B4	86	12
EPH-B3	74	2
EPH-B2	113	6
EPH-B1	100	10
EPH-A4	84	3
EPH-A2	78	2
EF2K	56	3
DYRK3	40	3
DYRK2	91	5
DYRK1A	80	5
DAPK1	46	0
CSK	74	3
CLK2	7	5
CK2	93	5
CK1 delta	78	3
CHK2	34	4
CHK1	92	10
CDK2-Cyclin A	6	2
CAMKK beta	57	8
CAMK1	27	0
BTK	58	10
BRSK2	46	1
BRSK1	58	7
Aurora B	42	3
Aurora A	91	7
ASK1	83	6
AMPK	50	0