Inhibitor | IKK-2 Inhibitor VIII  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
IKK beta	4	2
JAK2	4	2
CDK2-Cyclin A	6	2
RSK1	6	0
CLK2	7	5
ERK8	9	0
RSK2	11	1
PIM2	12	2
PIM1	18	3
TrkA	20	8
NUAK1	24	3
SmMLCK	25	1
CAMK1	27	0
PIM3	27	5
MELK	29	4
Lck	33	1
IR	33	7
MST2	34	1
CHK2	34	4
IGF-1R	35	7
YES1	38	13
TAK1	39	2
DYRK3	40	3
GCK	41	4
Aurora B	42	3
MLK3	44	4
PKD1	45	4
BRSK2	46	1
DAPK1	46	0
MEKK1	50	11
AMPK	50	0
MKK1	51	4
MINK1	52	2
PRK2	53	2
VEGFR1	53	3
S6K1	53	9
PKC alpha	55	3
MSK1	55	7
EF2K	56	3
CAMKK beta	57	8
TAO1	57	6
RIPK2	57	3
BTK	58	10
BRSK1	58	7
PHK	59	5
HIPK2	59	2
IRR	61	3
ROCK 2	61	4
PKB beta	62	5
HIPK1	62	2
PKB alpha	63	1
LKB1	65	3
MLK1	66	5
TTK	66	3
HER4	67	12
Src	68	3
p38 delta MAPK	68	8
JNK3	68	11
PAK4	69	2
SGK1	69	2
IRAK4	70	6
p38 beta MAPK	71	4
JNK2	71	3
p38 gamma MAPK	72	6
FGF-R1	72	8
GSK3 beta	73	8
CSK	74	3
EPH-B3	74	2
PAK5	75	8
PKC zeta	76	2
ERK2	76	1
MKK2	77	8
EPH-A2	78	2
CK1 delta	78	3
PAK2	78	8
HIPK3	79	5
ERK1	80	4
JNK1	80	4
DYRK1A	80	5
SYK	81	8
MARK3	82	6
PAK6	83	2
MKK6	83	13
ASK1	83	6
EPH-A4	84	3
MAPKAP-K3	85	9
TBK1	86	9
EPH-B4	86	12
PLK1	87	14
PRAK	88	8
MNK2	89	4
MNK1	90	13
p38 alpha MAPK	91	7
Aurora A	91	7
DYRK2	91	5
CHK1	92	10
CK2	93	5
NEK2a	94	6
PDK1	94	8
MARK1	95	5
PKA	95	7
MAPKAP-K2	95	4
IKK epsilon	96	8
MARK2	96	11
EPH-B1	100	10
NEK6	101	5
SRPK1	101	5
MST4	102	5
MARK4	102	5
EPH-B2	113	6

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
IKK beta	6	0
JAK2	27	5
CDK2-Cyclin A	32	1
PIM2	34	2
RSK2	39	6
CLK2	43	10
RSK1	45	6
IR	51	13
NUAK1	53	3
PIM3	56	3
ERK8	59	2
CHK2	60	4
MEKK1	62	1
PIM1	63	7
MINK1	66	11
Aurora B	67	12
TrkA	68	1
DAPK1	68	8
SmMLCK	70	1
HER4	71	1
TAK1	73	3
JNK3	73	6
MLK1	73	0
MKK6	76	4
GCK	77	3
PHK	77	4
TAO1	77	1
LKB1	78	8
YES1	79	0
HIPK2	80	5
RIPK2	80	13
TBK1	80	9
GSK3 beta	80	3
PKB alpha	81	9
Lck	82	8
JNK2	83	4
PLK1	83	5
PAK2	83	12
CSK	83	11
MST2	83	7
PKA	83	1
PAK5	84	5
DYRK3	84	1
AMPK	85	2
p38 delta MAPK	85	12
CAMK1	85	6
PKB beta	85	2
NEK2a	85	5
ERK1	85	10
CK1 delta	86	6
IGF-1R	86	12
IKK epsilon	87	1
MAPKAP-K3	87	12
MLK3	87	12
ROCK 2	88	13
MARK1	88	11
PKC zeta	88	6
p38 beta MAPK	88	11
SYK	88	12
S6K1	88	8
MELK	88	1
TTK	89	10
MARK2	89	1
Src	89	8
PAK6	89	9
EPH-B4	90	11
PRAK	90	12
PDK1	90	1
EF2K	90	3
CK2	91	2
DYRK2	91	3
BRSK2	92	11
SRPK1	92	8
PRK2	94	7
p38 gamma MAPK	94	3
EPH-B3	94	15
CHK1	95	14
SGK1	96	4
EPH-B1	96	9
FGF-R1	97	0
DYRK1A	99	4
EPH-A2	99	13
NEK6	99	7
MNK1	101	3
VEGFR1	101	11
ERK2	101	4
p38 alpha MAPK	102	15
ASK1	102	14
MSK1	105	5
CAMKK beta	106	1
PKD1	106	9
BRSK1	107	5
MKK2	107	5
EPH-A4	107	14
JNK1	110	1
Aurora A	111	1
PAK4	112	13
MST4	113	0
MNK2	113	3
HIPK1	113	8
MAPKAP-K2	115	1
MARK4	115	6
PKC alpha	117	7
IRR	117	7
MKK1	117	2
MARK3	118	10
EPH-B2	119	12
BTK	122	13
IRAK4	124	2
HIPK3	129	2