Inhibitor | IKK-2 Inhibitor VIII  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	85	2
ASK1	102	14
Aurora A	111	1
Aurora B	67	12
BRSK1	107	5
BRSK2	92	11
BTK	122	13
CAMK1	85	6
CAMKK beta	106	1
CDK2-Cyclin A	32	1
CHK1	95	14
CHK2	60	4
CK1 delta	86	6
CK2	91	2
CLK2	43	10
CSK	83	11
DAPK1	68	8
DYRK1A	99	4
DYRK2	91	3
DYRK3	84	1
EF2K	90	3
EPH-A2	99	13
EPH-A4	107	14
EPH-B1	96	9
EPH-B2	119	12
EPH-B3	94	15
EPH-B4	90	11
ERK1	85	10
ERK2	101	4
ERK8	59	2
FGF-R1	97	0
GCK	77	3
GSK3 beta	80	3
HER4	71	1
HIPK1	113	8
HIPK2	80	5
HIPK3	129	2
IGF-1R	86	12
IKK beta	6	0
IKK epsilon	87	1
IR	51	13
IRAK4	124	2
IRR	117	7
JAK2	27	5
JNK1	110	1
JNK2	83	4
JNK3	73	6
Lck	82	8
LKB1	78	8
MAPKAP-K2	115	1
MAPKAP-K3	87	12
MARK1	88	11
MARK2	89	1
MARK3	118	10
MARK4	115	6
MEKK1	62	1
MELK	88	1
MINK1	66	11
MKK1	117	2
MKK2	107	5
MKK6	76	4
MLK1	73	0
MLK3	87	12
MNK1	101	3
MNK2	113	3
MSK1	105	5
MST2	83	7
MST4	113	0
NEK2a	85	5
NEK6	99	7
NUAK1	53	3
p38 alpha MAPK	102	15
p38 beta MAPK	88	11
p38 delta MAPK	85	12
p38 gamma MAPK	94	3
PAK2	83	12
PAK4	112	13
PAK5	84	5
PAK6	89	9
PDK1	90	1
PHK	77	4
PIM1	63	7
PIM2	34	2
PIM3	56	3
PKA	83	1
PKB alpha	81	9
PKB beta	85	2
PKC alpha	117	7
PKC zeta	88	6
PKD1	106	9
PLK1	83	5
PRAK	90	12
PRK2	94	7
RIPK2	80	13
ROCK 2	88	13
RSK1	45	6
RSK2	39	6
S6K1	88	8
SGK1	96	4
SmMLCK	70	1
Src	89	8
SRPK1	92	8
SYK	88	12
TAK1	73	3
TAO1	77	1
TBK1	80	9
TrkA	68	1
TTK	89	10
VEGFR1	101	11
YES1	79	0

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	50	0
ASK1	83	6
Aurora A	91	7
Aurora B	42	3
BRSK1	58	7
BRSK2	46	1
BTK	58	10
CAMK1	27	0
CAMKK beta	57	8
CDK2-Cyclin A	6	2
CHK1	92	10
CHK2	34	4
CK1 delta	78	3
CK2	93	5
CLK2	7	5
CSK	74	3
DAPK1	46	0
DYRK1A	80	5
DYRK2	91	5
DYRK3	40	3
EF2K	56	3
EPH-A2	78	2
EPH-A4	84	3
EPH-B1	100	10
EPH-B2	113	6
EPH-B3	74	2
EPH-B4	86	12
ERK1	80	4
ERK2	76	1
ERK8	9	0
FGF-R1	72	8
GCK	41	4
GSK3 beta	73	8
HER4	67	12
HIPK1	62	2
HIPK2	59	2
HIPK3	79	5
IGF-1R	35	7
IKK beta	4	2
IKK epsilon	96	8
IR	33	7
IRAK4	70	6
IRR	61	3
JAK2	4	2
JNK1	80	4
JNK2	71	3
JNK3	68	11
Lck	33	1
LKB1	65	3
MAPKAP-K2	95	4
MAPKAP-K3	85	9
MARK1	95	5
MARK2	96	11
MARK3	82	6
MARK4	102	5
MEKK1	50	11
MELK	29	4
MINK1	52	2
MKK1	51	4
MKK2	77	8
MKK6	83	13
MLK1	66	5
MLK3	44	4
MNK1	90	13
MNK2	89	4
MSK1	55	7
MST2	34	1
MST4	102	5
NEK2a	94	6
NEK6	101	5
NUAK1	24	3
p38 alpha MAPK	91	7
p38 beta MAPK	71	4
p38 delta MAPK	68	8
p38 gamma MAPK	72	6
PAK2	78	8
PAK4	69	2
PAK5	75	8
PAK6	83	2
PDK1	94	8
PHK	59	5
PIM1	18	3
PIM2	12	2
PIM3	27	5
PKA	95	7
PKB alpha	63	1
PKB beta	62	5
PKC alpha	55	3
PKC zeta	76	2
PKD1	45	4
PLK1	87	14
PRAK	88	8
PRK2	53	2
RIPK2	57	3
ROCK 2	61	4
RSK1	6	0
RSK2	11	1
S6K1	53	9
SGK1	69	2
SmMLCK	25	1
Src	68	3
SRPK1	101	5
SYK	81	8
TAK1	39	2
TAO1	57	6
TBK1	86	9
TrkA	20	8
TTK	66	3
VEGFR1	53	3
YES1	38	13