Inhibitor | IKK Inhibitor VII  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
IKK Inhibitor VII   C28H29N5OS 483.60 873225-46-8 9549298 IKK Waelchli R. (2006) Bioorg. Med. Chem. Lett. 16 108

Screening Results Chart

Screening Results Tables

Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 49 0
ASK1 80 1
Aurora A 17 2
Aurora B 52 2
BRSK1 50 5
BRSK2 52 3
BTK 47 2
CAMK1 48 5
CAMKK beta 69 6
CDK2-Cyclin A 12 1
CHK1 57 2
CHK2 98 0
CK1 delta 89 0
CK2 66 1
CLK2 15 1
CSK 60 4
DAPK1
6
 2
DYRK1A 70 3
DYRK2 16 2
DYRK3 37 2
EF2K 77 0
EPH-A2 42 2
EPH-A4 45 2
EPH-B1 26 2
EPH-B2 35 2
EPH-B3 26 0
EPH-B4 37 3
ERK1 69 8
ERK2 78 1
ERK8
6
 2
FGF-R1 44 4
GCK 39 2
GSK3 beta 24 3
HER4 57 10
HIPK1 35 2
HIPK2 12 2
HIPK3 49 4
IGF-1R 37 6
IKK beta
6
 1
IKK epsilon 15 3
IR 20 3
IRAK4 79 8
IRR 54 6
JAK2
2
 1
JNK1 51 3
JNK2 74 7
JNK3 41 5
Lck 16 1
LKB1 80 12
MAPKAP-K2 96 3
MAPKAP-K3 100 3
MARK1 52 0
MARK2 75 2
MARK3 47 0
MARK4 42 12
MEKK1 79 2
MELK 105 3
MINK1 35 3
MKK1 60 0
MKK2 85 7
MKK6 94 5
MLK1 30 1
MLK3
7
 0
MNK1 43 6
MNK2 45 4
MSK1 72 12
MST2 74 8
MST4 143 2
NEK2a 88 0
NEK6 85 0
NUAK1 26 1
p38 alpha MAPK 91 12
p38 beta MAPK 65 4
p38 delta MAPK 77 3
p38 gamma MAPK 86 4
PAK2 71 11
PAK4 65 2
PAK5 64 3
PAK6 77 5
PDK1 82 5
PHK 57 5
PIM1 78 5
PIM2 95 2
PIM3 64 1
PKA 80 1
PKB alpha 67 3
PKB beta 73 7
PKC alpha 71 2
PKC zeta 98 6
PKD1 32 0
PLK1 84 1
PRAK 72 2
PRK2 27 3
RIPK2 34 3
ROCK 2 29 0
RSK1 75 12
RSK2 83 0
S6K1 69 7
SGK1 24 2
SmMLCK 87 1
Src 36 4
SRPK1 92 7
SYK 30 2
TAK1 13 2
TAO1 57 2
TBK1 23 2
TrkA 18 2
TTK 57 4
VEGFR1 15 2
YES1 25 4
Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
AMPK 22 4
ASK1 32 6
Aurora A
3
 1
Aurora B 17 4
BRSK1 43 0
BRSK2 25 1
BTK 16 2
CAMK1
8
 2
CAMKK beta 46 5
CDK2-Cyclin A
3
 1
CHK1
10
 1
CHK2 62 0
CK1 delta 72 1
CK2 30 4
CLK2
3
 0
CSK 28 2
DAPK1
4
 0
DYRK1A 24 1
DYRK2
3
 1
DYRK3
10
 0
EF2K 55 7
EPH-A2 30 4
EPH-A4 16 0
EPH-B1
4
 1
EPH-B2
8
 0
EPH-B3
6
 1
EPH-B4 11 2
ERK1 64 9
ERK2 51 0
ERK8
1
 0
FGF-R1 20 8
GCK 12 0
GSK3 beta
6
 1
HER4 37 8
HIPK1
8
 0
HIPK2
8
 3
HIPK3 11 2
IGF-1R
3
 1
IKK beta
3
 0
IKK epsilon
6
 1
IR
3
 1
IRAK4 38 5
IRR 27 8
JAK2
1
 0
JNK1 14 0
JNK2 37 2
JNK3 35 5
Lck
3
 1
LKB1 77 3
MAPKAP-K2 93 6
MAPKAP-K3 71 5
MARK1 33 4
MARK2 68 6
MARK3 16 1
MARK4 32 2
MEKK1 68 4
MELK 58 10
MINK1
10
 3
MKK1 19 2
MKK2 42 3
MKK6 71 6
MLK1 34 4
MLK3
5
 0
MNK1 27 2
MNK2 37 4
MSK1 43 1
MST2 30 2
MST4 156 6
NEK2a 54 1
NEK6 76 7
NUAK1 19 3
p38 alpha MAPK 81 2
p38 beta MAPK 20 7
p38 delta MAPK 61 11
p38 gamma MAPK 69 7
PAK2 38 6
PAK4 36 5
PAK5 27 0
PAK6 85 7
PDK1 61 0
PHK 14 1
PIM1 27 1
PIM2 91 6
PIM3 24 1
PKA 67 8
PKB alpha 47 1
PKB beta 44 6
PKC alpha 26 4
PKC zeta 81 6
PKD1 18 3
PLK1 60 10
PRAK 38 1
PRK2
6
 1
RIPK2
9
 1
ROCK 2
5
 1
RSK1 24 1
RSK2 39 1
S6K1 29 2
SGK1
4
 1
SmMLCK 41 3
Src 14 6
SRPK1 90 2
SYK 11 1
TAK1
2
 1
TAO1 25 5
TBK1 17 5
TrkA 14 2
TTK 33 1
VEGFR1 11 1
YES1 19 4