Inhibitor | A-83-01  

Screen Conc: 1.00µM

Kinase Sort ascending	% Activity Remaining	Standard Deviation
YES1	70	5
VEGFR1	8	1
TTK	98	6
TrkA	99	11
TBK1	106	1
TAK1	81	9
SYK	106	2
SRPK1	84	1
Src	75	1
SmMLCK	89	1
SGK1	103	14
S6K1	105	13
RSK2	109	8
RSK1	95	2
ROCK 2	104	2
RIPK2	9	3
PRK2	91	3
PRAK	99	16
PLK1	106	7
PKD1	32	9
PKC zeta	100	3
PKC alpha	102	7
PKB beta	96	5
PKB alpha	106	9
PKA	99	5
PIM3	117	11
PIM2	94	3
PIM1	97	4
PHK	112	4
PDK1	88	0
PAK6	113	19
PAK5	102	4
PAK4	93	4
PAK2	101	12
p38 gamma MAPK	88	8
p38 delta MAPK	94	4
p38 beta MAPK	61	7
p38 alpha MAPK	16	1
NUAK1	84	4
NEK6	100	5
NEK2a	92	3
MST4	99	1
MST2	100	6
MSK1	101	0
MNK2	91	2
MNK1	93	1
MLK3	107	4
MLK1	86	2
MKK1	98	1
MINK1	13	2
MELK	105	3
MEKK1	111	0
MARK4	87	2
MARK3	98	7
MARK2	110	9
MARK1	113	7
MAPKAP-K3	97	4
MAPKAP-K2	108	2
LKB1	99	11
Lck	62	3
JNK3	99	7
JNK2	90	7
JNK1	101	4
JAK2	93	4
IRR	103	3
IRAK4	99	5
IR	94	6
IKK epsilon	106	0
IKK beta	100	12
IGF-1R	103	11
HIPK3	99	1
HIPK2	95	12
HIPK1	98	11
HER4	82	15
GSK3 beta	79	4
GCK	68	7
FGF-R1	37	2
ERK8	93	4
ERK2	94	2
ERK1	100	5
EPH-B4	93	19
EPH-B3	104	0
EPH-B2	95	5
EPH-A4	98	3
EPH-A2	92	14
EF2K	100	3
DYRK3	93	4
DYRK2	95	7
DYRK1A	104	1
DAPK1	90	2
CSK	93	1
CLK2	98	0
CK2	104	11
CK1 delta	46	5
CHK2	110	6
CHK1	105	3
CDK2-Cyclin A	102	11
CAMKK beta	104	2
CAMK1	107	13
BTK	104	5
BRSK2	92	14
BRSK1	95	7
Aurora B	102	1
Aurora A	107	3
AMPK	82	4

Screen Conc: 0.10µM

Kinase Sort ascending	% Activity Remaining	Standard Deviation
YES1	106	4
VEGFR1	27	0
TTK	113	0
TrkA	118	2
TBK1	102	7
TAK1	99	9
SYK	109	10
SRPK1	101	7
Src	102	1
SmMLCK	104	8
SGK1	107	1
S6K1	108	2
RSK2	126	3
RSK1	110	6
ROCK 2	96	2
RIPK2	26	6
PRK2	105	12
PRAK	113	7
PLK1	99	11
PKD1	80	1
PKC zeta	98	0
PKC alpha	97	5
PKB beta	108	3
PKB alpha	102	5
PKA	109	2
PIM3	91	4
PIM2	97	4
PIM1	105	3
PHK	100	11
PDK1	103	8
PAK6	111	12
PAK5	107	2
PAK4	89	6
PAK2	111	17
p38 gamma MAPK	102	13
p38 delta MAPK	91	20
p38 beta MAPK	89	15
p38 alpha MAPK	56	1
NUAK1	96	10
NEK6	107	3
NEK2a	109	8
MST4	95	2
MST2	107	0
MSK1	110	6
MNK2	81	5
MNK1	103	1
MLK3	104	2
MLK1	96	7
MKK1	111	20
MINK1	66	2
MELK	111	2
MEKK1	130	15
MARK4	98	2
MARK3	101	4
MARK2	121	8
MARK1	107	3
MAPKAP-K3	107	3
MAPKAP-K2	117	3
LKB1	101	5
Lck	105	7
JNK3	119	3
JNK2	105	6
JNK1	111	3
JAK2	107	18
IRR	98	5
IRAK4	101	3
IR	108	7
IKK epsilon	112	5
IKK beta	107	1
IGF-1R	97	5
HIPK3	105	8
HIPK2	104	8
HIPK1	96	4
HER4	104	1
GSK3 beta	99	1
GCK	98	3
FGF-R1	64	3
ERK8	108	16
ERK2	104	11
ERK1	105	15
EPH-B4	93	2
EPH-B3	112	6
EPH-B2	113	2
EPH-A4	108	1
EPH-A2	105	5
EF2K	102	4
DYRK3	102	8
DYRK2	100	0
DYRK1A	109	11
DAPK1	94	3
CSK	97	2
CLK2	106	10
CK2	102	0
CK1 delta	90	8
CHK2	115	10
CHK1	107	10
CDK2-Cyclin A	93	4
CAMKK beta	100	10
CAMK1	103	18
BTK	110	5
BRSK2	117	6
BRSK1	110	12
Aurora B	98	5
Aurora A	120	7
AMPK	99	3