Inhibitor | PD 0332991  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
HIPK2	8	2
DYRK1A	9	1
ERK8	13	1
CK2	13	4
MELK	14	1
GCK	15	1
DYRK3	16	9
PLK1	18	3
PKD1	18	1
TrkA	18	0
TAK1	21	0
PHK	22	2
CAMKK beta	27	1
CDK2-Cyclin A	28	3
NUAK1	29	11
RSK1	30	1
IRR	30	0
SmMLCK	35	1
HIPK3	35	11
AMPK	37	29
JAK2	39	3
RSK2	41	10
MINK1	41	2
PIM3	42	13
DYRK2	44	6
VEGFR1	47	2
JNK2	50	23
FGF-R1	51	6
Lck	55	20
IGF-1R	58	2
PIM1	59	9
CHK1	59	1
MARK4	60	6
HIPK1	60	1
YES1	61	0
JNK3	61	3
PIM2	62	3
MLK1	63	1
SGK1	64	9
GSK3 beta	65	3
Aurora B	65	1
BRSK2	66	0
MARK3	67	0
IRAK4	67	12
IR	67	2
HER4	68	2
CAMK1	69	1
ERK2	69	5
NEK2a	70	6
JNK1	71	2
PAK5	71	1
Src	71	2
LKB1	72	9
CK1 delta	72	10
MLK3	73	1
IKK epsilon	74	1
PKB beta	74	1
MARK1	79	3
MARK2	80	4
S6K1	82	4
MNK2	84	4
TTK	84	44
BRSK1	85	8
MSK1	85	2
IKK beta	87	7
PRK2	87	9
PKC alpha	87	7
PAK4	87	9
CHK2	89	0
ERK1	90	10
p38 delta MAPK	91	1
MKK1	91	1
ROCK 2	92	8
PAK6	92	0
NEK6	93	1
PAK2	93	7
PKC zeta	93	3
MEKK1	95	7
SYK	95	9
PKB alpha	96	9
EPH-A2	97	2
PKA	97	4
MAPKAP-K3	98	10
EPH-B3	98	6
MST2	99	8
MAPKAP-K2	99	24
MNK1	101	0
SRPK1	101	12
PDK1	102	9
EPH-A4	102	15
p38 gamma MAPK	102	7
p38 beta MAPK	103	6
BTK	104	38
Aurora A	104	10
PRAK	107	16
EPH-B4	107	2
p38 alpha MAPK	108	9
CSK	112	3
TBK1	112	29
EF2K	113	8
RIPK2	113	39
MST4	135	3

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
HIPK2	28	1
PKD1	44	4
ERK8	47	7
PLK1	49	8
IRR	52	1
DYRK1A	54	4
CK2	55	4
DYRK3	57	2
TTK	61	0
TrkA	66	2
MELK	69	12
CAMKK beta	69	1
PIM1	70	28
PHK	71	10
GCK	72	21
PIM3	73	1
AMPK	74	2
CDK2-Cyclin A	75	4
TAK1	76	1
NUAK1	78	12
JNK2	80	20
SGK1	82	8
CK1 delta	82	3
HIPK3	83	0
PKB beta	84	0
JNK1	84	10
DYRK2	84	5
IGF-1R	85	1
RSK1	85	0
Aurora B	87	7
JAK2	87	1
CHK1	88	2
MARK4	88	4
PRK2	89	1
p38 delta MAPK	89	11
MINK1	89	3
BRSK1	90	10
Lck	91	48
PAK5	91	3
PAK6	91	1
LKB1	91	6
BTK	92	8
PKB alpha	92	12
MARK2	93	15
MEKK1	93	3
SmMLCK	94	7
PAK4	94	5
MAPKAP-K2	94	7
VEGFR1	95	3
MARK3	95	9
BRSK2	96	5
PKC alpha	96	12
p38 beta MAPK	96	4
MNK2	96	6
PAK2	97	3
p38 alpha MAPK	97	7
MNK1	97	6
IKK beta	97	3
IKK epsilon	97	1
CAMK1	98	10
S6K1	98	23
IRAK4	98	3
MSK1	98	0
ERK2	99	3
PKA	99	2
RIPK2	99	18
Src	99	6
PKC zeta	99	2
NEK6	99	8
MARK1	99	13
RSK2	99	0
TBK1	99	10
PRAK	99	13
JNK3	100	8
MLK1	100	6
MLK3	101	0
HIPK1	101	4
MST4	101	6
EPH-A4	101	10
ROCK 2	102	8
PDK1	102	1
GSK3 beta	103	4
p38 gamma MAPK	103	4
PIM2	104	4
SRPK1	105	3
EF2K	105	5
CHK2	105	13
MAPKAP-K3	105	6
CSK	106	7
EPH-A2	107	5
EPH-B3	108	13
NEK2a	109	2
IR	110	1
MKK1	111	7
HER4	111	8
SYK	111	25
EPH-B4	111	2
YES1	112	7
MST2	113	4
ERK1	117	11
Aurora A	117	7
FGF-R1	120	5