Inhibitor | GSK269962A  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	89	4
ASK1	113	9
Aurora A	94	1
Aurora B	86	5
BRSK1	93	1
BRSK2	91	2
BTK	97	4
CAMK1	97	12
CAMKK beta	87	6
CDK2-Cyclin A	107	5
CHK1	87	1
CHK2	96	2
CK1 delta	102	3
CK2	116	2
CLK2	101	2
CSK	86	8
DAPK1	91	0
DYRK1A	100	1
DYRK2	99	9
DYRK3	96	3
EF2K	71	4
EPH-A2	92	2
EPH-A4	110	13
EPH-B1	93	9
EPH-B2	128	3
EPH-B3	115	13
EPH-B4	102	4
ERK1	106	2
ERK2	98	9
ERK8	92	1
FGF-R1	96	7
GCK	101	2
GSK3 beta	67	1
HER4	77	6
HIPK1	83	1
HIPK2	72	8
HIPK3	94	5
IGF-1R	90	4
IKK beta	104	0
IKK epsilon	93	15
IR	98	1
IRAK4	94	7
IRR	91	8
JAK2	101	5
JNK1	91	6
JNK2	99	5
JNK3	92	3
Lck	101	5
LKB1	82	2
MAPKAP-K2	101	9
MAPKAP-K3	97	5
MARK1	100	3
MARK2	89	2
MARK3	90	14
MARK4	105	6
MEKK1	71	9
MELK	77	10
MINK1	87	2
MKK1	109	10
MKK2	90	1
MKK6	105	3
MLK1	85	3
MLK3	90	1
MNK1	108	8
MNK2	82	0
MSK1	11	0
MST2	109	7
MST4	108	4
NEK2a	96	3
NEK6	109	1
NUAK1	100	2
p38 alpha MAPK	106	13
p38 beta MAPK	106	2
p38 delta MAPK	105	2
p38 gamma MAPK	98	1
PAK2	102	2
PAK4	94	2
PAK5	88	5
PAK6	102	8
PDK1	116	0
PHK	104	6
PIM1	90	9
PIM2	97	4
PIM3	93	1
PKA	67	2
PKB alpha	103	1
PKB beta	64	0
PKC alpha	83	2
PKC zeta	41	4
PKD1	99	5
PLK1	83	4
PRAK	91	1
PRK2	32	1
RIPK2	99	1
ROCK 2	7	0
RSK1	32	3
RSK2	78	1
S6K1	21	4
SGK1	94	6
SmMLCK	65	3
Src	96	4
SRPK1	108	9
SYK	99	5
TAK1	88	8
TAO1	98	7
TBK1	92	0
TrkA	105	2
TTK	84	4
VEGFR1	94	14
YES1	86	2

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	92	2
ASK1	98	12
Aurora A	57	2
Aurora B	79	7
BRSK1	84	0
BRSK2	83	1
BTK	92	6
CAMK1	91	5
CAMKK beta	89	5
CDK2-Cyclin A	99	3
CHK1	92	1
CHK2	57	1
CK1 delta	95	12
CK2	96	2
CLK2	89	4
CSK	70	10
DAPK1	82	2
DYRK1A	98	1
DYRK2	73	2
DYRK3	80	1
EF2K	74	5
EPH-A2	102	1
EPH-A4	95	13
EPH-B1	111	4
EPH-B2	120	9
EPH-B3	97	2
EPH-B4	103	6
ERK1	92	1
ERK2	82	3
ERK8	39	0
FGF-R1	77	9
GCK	85	3
GSK3 beta	15	4
HER4	88	8
HIPK1	61	3
HIPK2	28	1
HIPK3	96	7
IGF-1R	96	9
IKK beta	86	2
IKK epsilon	65	10
IR	103	7
IRAK4	93	6
IRR	60	3
JAK2	65	2
JNK1	88	2
JNK2	101	5
JNK3	97	2
Lck	108	3
LKB1	81	2
MAPKAP-K2	101	5
MAPKAP-K3	86	3
MARK1	88	7
MARK2	97	0
MARK3	95	8
MARK4	78	8
MEKK1	46	3
MELK	64	5
MINK1	79	5
MKK1	105	1
MKK2	87	2
MKK6	111	3
MLK1	95	7
MLK3	82	8
MNK1	99	8
MNK2	90	5
MSK1	3	0
MST2	103	11
MST4	108	8
NEK2a	83	6
NEK6	103	4
NUAK1	42	1
p38 alpha MAPK	88	6
p38 beta MAPK	99	9
p38 delta MAPK	84	2
p38 gamma MAPK	85	0
PAK2	96	1
PAK4	104	1
PAK5	68	6
PAK6	90	4
PDK1	102	10
PHK	110	3
PIM1	39	6
PIM2	71	7
PIM3	73	10
PKA	19	0
PKB alpha	61	4
PKB beta	51	13
PKC alpha	75	7
PKC zeta	12	1
PKD1	86	3
PLK1	92	5
PRAK	98	4
PRK2	9	1
RIPK2	83	0
ROCK 2	2	1
RSK1	7	1
RSK2	35	5
S6K1	20	4
SGK1	53	5
SmMLCK	79	8
Src	102	3
SRPK1	80	5
SYK	96	4
TAK1	55	11
TAO1	88	6
TBK1	87	5
TrkA	104	15
TTK	81	6
VEGFR1	87	11
YES1	111	5