Inhibitor | Sunitinib  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	50	2
ASK1	87	2
Aurora A	117	5
Aurora B	46	11
BRSK1	95	3
BRSK2	117	11
BTK	81	2
CAMK1	49	5
CAMKK beta	80	6
CDK2-Cyclin A	105	8
CHK1	70	7
CHK2	34	2
CK1 delta	79	2
CK2	96	8
CLK2	30	0
CSK	99	7
DAPK1	65	2
DYRK1A	91	1
DYRK2	88	9
DYRK3	96	9
EF2K	88	4
EPH-A2	91	1
EPH-A4	87	6
EPH-B1	94	0
EPH-B2	110	2
EPH-B3	116	1
EPH-B4	117	1
ERK1	105	13
ERK2	101	4
ERK8	111	2
FGF-R1	88	8
GCK	71	3
GSK3 beta	96	1
HER4	110	3
HIPK1	95	6
HIPK2	64	8
HIPK3	91	2
IGF-1R	74	7
IKK beta	117	15
IKK epsilon	88	1
IR	125	9
IRAK4	74	5
IRR	93	4
JAK2	73	0
JNK1	102	1
JNK2	90	2
JNK3	97	1
Lck	63	3
LKB1	100	11
MAPKAP-K2	109	9
MAPKAP-K3	91	2
MARK1	93	8
MARK2	118	11
MARK3	96	6
MARK4	91	5
MEKK1	92	5
MELK	57	6
MINK1	76	2
MKK1	47	7
MKK2	41	1
MKK6	94	11
MLK1	109	7
MLK3	72	8
MNK1	97	13
MNK2	96	0
MSK1	83	14
MST2	70	7
MST4	113	1
NEK2a	104	6
NEK6	97	1
NUAK1	29	2
p38 alpha MAPK	102	4
p38 beta MAPK	115	0
p38 delta MAPK	92	11
p38 gamma MAPK	100	2
PAK2	96	2
PAK4	79	7
PAK5	120	3
PAK6	100	2
PDK1	89	7
PHK	12	5
PIM1	100	0
PIM2	94	12
PIM3	93	12
PKA	94	5
PKB alpha	110	7
PKB beta	76	12
PKC alpha	87	1
PKC zeta	99	9
PKD1	89	1
PLK1	97	8
PRAK	89	7
PRK2	101	7
RIPK2	117	4
ROCK 2	87	8
RSK1	60	3
RSK2	100	4
S6K1	78	6
SGK1	93	4
SmMLCK	63	4
Src	75	3
SRPK1	98	1
SYK	125	14
TAK1	32	1
TAO1	101	1
TBK1	84	10
TrkA	25	3
TTK	92	11
VEGFR1	30	0
YES1	50	7

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	19	3
ASK1	78	5
Aurora A	100	3
Aurora B	27	6
BRSK1	54	3
BRSK2	58	0
BTK	45	0
CAMK1	66	2
CAMKK beta	42	4
CDK2-Cyclin A	109	4
CHK1	21	1
CHK2	9	1
CK1 delta	9	0
CK2	87	1
CLK2	6	0
CSK	93	3
DAPK1	23	0
DYRK1A	63	0
DYRK2	81	10
DYRK3	72	2
EF2K	93	0
EPH-A2	65	2
EPH-A4	57	0
EPH-B1	87	15
EPH-B2	63	1
EPH-B3	82	6
EPH-B4	86	1
ERK1	117	13
ERK2	116	9
ERK8	103	0
FGF-R1	28	8
GCK	17	1
GSK3 beta	109	4
HER4	86	7
HIPK1	63	1
HIPK2	25	0
HIPK3	71	4
IGF-1R	19	3
IKK beta	79	3
IKK epsilon	61	0
IR	26	2
IRAK4	28	3
IRR	73	0
JAK2	28	8
JNK1	98	10
JNK2	103	4
JNK3	79	2
Lck	19	1
LKB1	103	2
MAPKAP-K2	95	4
MAPKAP-K3	93	5
MARK1	48	1
MARK2	85	7
MARK3	100	0
MARK4	37	3
MEKK1	41	3
MELK	18	0
MINK1	17	3
MKK1	17	1
MKK2	10	2
MKK6	105	7
MLK1	74	1
MLK3	19	0
MNK1	86	0
MNK2	81	4
MSK1	63	6
MST2	21	1
MST4	98	8
NEK2a	95	5
NEK6	78	4
NUAK1	24	2
p38 alpha MAPK	100	6
p38 beta MAPK	99	5
p38 delta MAPK	98	6
p38 gamma MAPK	95	0
PAK2	97	4
PAK4	67	1
PAK5	75	5
PAK6	83	5
PDK1	80	3
PHK	5	4
PIM1	87	0
PIM2	105	10
PIM3	59	1
PKA	102	4
PKB alpha	95	2
PKB beta	72	4
PKC alpha	91	7
PKC zeta	114	10
PKD1	46	2
PLK1	94	3
PRAK	85	15
PRK2	82	7
RIPK2	95	7
ROCK 2	76	4
RSK1	18	0
RSK2	60	14
S6K1	60	2
SGK1	66	4
SmMLCK	14	3
Src	34	3
SRPK1	104	15
SYK	94	9
TAK1	8	1
TAO1	88	3
TBK1	41	2
TrkA	10	4
TTK	65	7
VEGFR1	16	1
YES1	15	2