Inhibitor | Bay 65-1942  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
PIM3	7	1
PKC zeta	10	1
ERK8	10	1
IKK beta	12	1
CAMK1	13	0
SGK1	13	0
CDK2-Cyclin A	14	0
PIM1	15	0
PHK	21	1
DYRK3	24	1
MSK1	31	2
PKC alpha	31	5
HIPK2	34	3
PRK2	36	0
SmMLCK	37	5
ROCK 2	39	0
PIM2	40	12
CK1 delta	43	3
BRSK2	45	4
IRR	45	4
RSK1	46	2
CHK2	46	7
PKD1	48	1
YES1	49	4
RSK2	53	3
AMPK	54	5
PAK4	54	8
PKB alpha	55	15
MELK	58	17
PRAK	58	13
JNK1	61	0
PKB beta	61	3
MKK1	62	7
PKA	65	4
SRPK1	65	5
p38 gamma MAPK	66	2
MST2	67	2
EF2K	67	0
S6K1	68	0
CK2	70	0
IGF-1R	71	29
PAK5	72	1
p38 delta MAPK	73	4
MNK1	74	5
ERK2	74	14
IKK epsilon	74	6
Lck	74	4
p38 beta MAPK	74	12
DYRK2	77	9
PAK6	78	1
p38 alpha MAPK	78	7
CAMKK beta	78	9
FGF-R1	79	2
NEK2a	81	8
DYRK1A	82	6
BTK	83	0
Src	83	1
TBK1	84	4
EPH-A2	84	3
MST4	85	13
ERK1	86	3
MNK2	87	7
PLK1	87	2
CHK1	88	4
SYK	91	17
CSK	92	5
EPH-B3	93	9
JNK2	93	5
NEK6	93	11
MARK3	94	2
IR	96	9
GSK3 beta	99	6
PDK1	100	7
VEGFR1	116	1
MAPKAP-K2	147	91

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
IKK beta	28	17
PIM3	44	2
ERK8	53	1
CAMK1	54	3
SGK1	55	4
CDK2-Cyclin A	58	5
PRK2	69	7
PHK	70	8
DYRK3	71	7
MSK1	71	4
PAK6	72	1
ROCK 2	73	0
PRAK	74	1
SmMLCK	76	6
PIM1	76	7
JNK1	76	4
PKC zeta	76	47
CHK2	77	6
PKC alpha	77	7
IRR	78	6
MKK1	79	0
PKA	79	6
PKD1	79	1
MELK	79	23
RSK2	80	8
IGF-1R	80	18
ERK2	81	0
CK1 delta	81	5
PAK5	82	1
RSK1	83	0
IKK epsilon	83	0
NEK2a	83	6
PLK1	83	7
MST2	84	3
HIPK2	84	4
p38 gamma MAPK	85	0
PKB alpha	87	1
AMPK	87	0
Lck	88	4
PKB beta	88	11
PIM2	88	24
EF2K	88	6
p38 delta MAPK	88	7
BRSK2	89	2
PAK4	89	13
EPH-B3	89	13
JNK2	90	6
Src	91	3
CSK	91	11
p38 alpha MAPK	91	0
p38 beta MAPK	91	1
TBK1	91	2
CAMKK beta	94	0
YES1	94	2
IR	94	1
CK2	95	7
FGF-R1	96	6
EPH-A2	96	7
MNK1	97	8
NEK6	98	3
ERK1	98	22
SRPK1	98	6
MNK2	98	5
DYRK1A	99	3
DYRK2	99	8
MARK3	100	8
BTK	100	7
S6K1	102	17
CHK1	102	4
MST4	105	4
PDK1	106	3
SYK	106	13
VEGFR1	112	2
MAPKAP-K2	120	37
GSK3 beta	126	6