Inhibitor | ER-27319  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	113	8
Aurora B	102	1
BRSK2	89	9
BTK	85	7
CAMK1	101	4
CAMKK beta	100	0
CDK2-Cyclin A	91	2
CHK1	95	9
CHK2	93	14
CK1 delta	121	1
CK2	93	5
CSK	97	5
DYRK1A	97	2
DYRK2	99	3
DYRK3	93	5
EF2K	122	0
EPH-A2	99	4
EPH-B3	86	13
ERK1	100	3
ERK2	95	7
ERK8	91	9
FGF-R1	79	5
GSK3 beta	106	0
HIPK2	99	7
IGF-1R	101	19
IKK beta	100	10
IKK epsilon	107	13
IR	76	4
IRR	80	3
JNK1	98	0
JNK2	97	10
Lck	106	8
MAPKAP-K2	88	9
MARK3	105	13
MELK	77	2
MKK1	92	11
MNK1	85	12
MNK2	102	10
MSK1	118	0
MST2	103	2
MST4	99	8
NEK2a	120	1
NEK6	84	4
p38 alpha MAPK	110	0
p38 beta MAPK	81	10
p38 delta MAPK	89	11
p38 gamma MAPK	98	7
PAK4	89	7
PAK5	85	2
PAK6	99	0
PDK1	100	5
PHK	106	11
PIM1	98	0
PIM2	96	2
PIM3	82	1
PKA	96	17
PKB alpha	108	12
PKB beta	123	0
PKC alpha	118	27
PKC zeta	83	12
PKD1	95	10
PLK1	105	6
PRAK	96	5
PRK2	113	2
ROCK 2	107	13
RSK1	101	1
RSK2	113	4
S6K1	130	8
SGK1	89	10
SmMLCK	105	8
Src	93	2
SRPK1	111	0
SYK	99	8
TBK1	88	0
VEGFR1	105	6
YES1	84	5

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	96	3
Aurora B	90	1
BRSK2	85	0
BTK	88	11
CAMK1	98	5
CAMKK beta	97	0
CDK2-Cyclin A	90	11
CHK1	97	6
CHK2	83	8
CK1 delta	107	8
CK2	69	5
CSK	100	10
DYRK1A	85	12
DYRK2	97	9
DYRK3	87	2
EF2K	120	1
EPH-A2	97	2
EPH-B3	85	4
ERK1	85	12
ERK2	100	4
ERK8	54	9
FGF-R1	83	9
GSK3 beta	107	1
HIPK2	97	20
IGF-1R	93	2
IKK beta	96	6
IKK epsilon	96	1
IR	73	2
IRR	65	10
JNK1	99	2
JNK2	96	11
Lck	86	3
MAPKAP-K2	93	8
MARK3	96	5
MELK	78	4
MKK1	89	2
MNK1	78	12
MNK2	90	0
MSK1	112	0
MST2	101	1
MST4	89	9
NEK2a	120	12
NEK6	100	0
p38 alpha MAPK	111	9
p38 beta MAPK	85	7
p38 delta MAPK	93	7
p38 gamma MAPK	101	5
PAK4	85	5
PAK5	100	7
PAK6	99	8
PDK1	87	0
PHK	89	0
PIM1	67	1
PIM2	95	0
PIM3	43	9
PKA	109	8
PKB alpha	101	1
PKB beta	117	3
PKC alpha	88	12
PKC zeta	81	0
PKD1	80	17
PLK1	113	7
PRAK	96	2
PRK2	96	0
ROCK 2	94	5
RSK1	78	6
RSK2	99	1
S6K1	109	8
SGK1	90	3
SmMLCK	92	6
Src	92	7
SRPK1	95	4
SYK	89	4
TBK1	98	11
VEGFR1	95	4
YES1	100	3