Inhibitor | SYK Inhibitor III  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	105	2
Aurora B	97	3
BRSK2	97	5
BTK	102	17
CAMK1	108	3
CAMKK beta	104	10
CDK2-Cyclin A	101	7
CHK1	98	9
CHK2	102	2
CK1 delta	106	14
CK2	104	3
CSK	100	8
DYRK1A	98	1
DYRK2	99	4
DYRK3	106	5
EF2K	127	2
EPH-A2	100	5
EPH-B3	103	9
ERK1	106	15
ERK2	102	4
ERK8	90	5
FGF-R1	111	9
GSK3 beta	136	17
HIPK2	112	0
IGF-1R	108	10
IKK beta	107	3
IKK epsilon	111	1
IR	76	18
IRR	89	9
JNK1	111	9
JNK2	100	1
Lck	114	12
MAPKAP-K2	94	5
MARK3	110	5
MELK	90	5
MKK1	96	2
MNK1	95	13
MNK2	103	11
MSK1	95	0
MST2	97	1
MST4	108	2
NEK2a	89	0
NEK6	101	0
p38 alpha MAPK	110	8
p38 beta MAPK	104	8
p38 delta MAPK	92	14
p38 gamma MAPK	100	6
PAK4	76	2
PAK5	86	1
PAK6	114	1
PDK1	116	11
PHK	117	4
PIM1	99	13
PIM2	115	2
PIM3	105	3
PKA	105	20
PKB alpha	117	2
PKB beta	105	2
PKC alpha	108	33
PKC zeta	106	3
PKD1	106	3
PLK1	104	9
PRAK	93	1
PRK2	117	1
ROCK 2	111	11
RSK1	104	1
RSK2	119	15
S6K1	105	2
SGK1	107	2
SmMLCK	111	3
Src	92	2
SRPK1	104	1
SYK	119	20
TBK1	97	2
VEGFR1	105	1
YES1	91	3

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	72	3
ASK1	106	10
Aurora A	45	4
Aurora B	87	4
BRSK1	79	3
BRSK2	63	7
BTK	37	3
CAMK1	26	4
CAMKK beta	82	9
CDK2-Cyclin A	79	3
CHK1	93	15
CHK2	88	7
CK1 delta	93	12
CK2	83	6
CLK2	79	6
CSK	86	2
DAPK1	80	7
DYRK1A	17	0
DYRK2	78	7
DYRK3	77	7
EF2K	84	4
EPH-A2	66	0
EPH-A4	76	1
EPH-B1	94	5
EPH-B2	116	1
EPH-B3	77	6
EPH-B4	84	5
ERK1	57	4
ERK2	76	3
ERK8	5	1
FGF-R1	27	1
GCK	64	1
GSK3 beta	76	6
HER4	27	7
HIPK1	73	0
HIPK2	68	7
HIPK3	88	6
IGF-1R	88	8
IKK beta	65	5
IKK epsilon	32	4
IR	85	15
IRAK4	87	9
IRR	71	2
JAK2	87	6
JNK1	97	3
JNK2	85	2
JNK3	80	2
Lck	100	9
LKB1	87	3
MAPKAP-K2	95	2
MAPKAP-K3	54	3
MARK1	87	4
MARK2	104	9
MARK3	79	3
MARK4	66	12
MEKK1	85	3
MELK	62	2
MINK1	33	5
MKK1	70	8
MKK2	92	8
MKK6	90	8
MLK1	73	0
MLK3	117	3
MNK1	91	1
MNK2	84	4
MSK1	78	3
MST2	55	5
MST4	25	1
NEK2a	4	1
NEK6	72	6
NUAK1	42	3
p38 alpha MAPK	100	4
p38 beta MAPK	85	1
p38 delta MAPK	91	6
p38 gamma MAPK	90	1
PAK2	44	2
PAK4	73	1
PAK5	94	7
PAK6	80	10
PDK1	86	1
PHK	87	3
PIM1	71	4
PIM2	79	6
PIM3	76	7
PKA	88	3
PKB alpha	100	7
PKB beta	7	0
PKC alpha	58	1
PKC zeta	68	5
PKD1	64	5
PLK1	63	2
PRAK	66	3
PRK2	88	6
RIPK2	88	5
ROCK 2	84	1
RSK1	80	8
RSK2	50	2
S6K1	66	6
SGK1	96	3
SmMLCK	88	10
Src	83	6
SRPK1	89	2
SYK	88	0
TAK1	74	4
TAO1	92	1
TBK1	108	13
TrkA	84	7
TTK	62	2
VEGFR1	27	1
YES1	73	3