Inhibitor | GW501516  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	94	8
Aurora B	110	10
BRSK2	91	6
BTK	92	8
CAMK1	95	19
CAMKK beta	86	5
CDK2-Cyclin A	87	14
CHK1	102	3
CHK2	81	17
CK1 delta	82	12
CK2	84	3
CSK	98	6
DYRK1A	87	4
DYRK2	103	5
DYRK3	83	6
EF2K	80	1
EPH-A2	103	8
EPH-B3	122	28
ERK1	115	10
ERK2	100	1
ERK8	103	7
FGF-R1	100	6
GSK3 beta	87	3
HIPK2	101	2
IGF-1R	87	2
IKK beta	220	133
IKK epsilon	92	0
IR	107	19
IRR	81	12
JNK1	83	11
JNK2	101	22
Lck	106	2
MAPKAP-K2	97	12
MARK3	93	9
MELK	79	4
MKK1	105	18
MNK1	89	4
MNK2	99	4
MSK1	96	4
MST2	97	9
MST4	104	9
NEK2a	94	5
NEK6	101	3
p38 alpha MAPK	82	1
p38 beta MAPK	91	5
p38 delta MAPK	102	0
p38 gamma MAPK	108	14
PAK4	87	5
PAK5	97	0
PAK6	97	0
PDK1	96	9
PHK	109	3
PIM1	79	1
PIM2	99	17
PIM3	86	4
PKA	110	6
PKB alpha	107	7
PKB beta	103	10
PKC alpha	96	6
PKC zeta	79	11
PKD1	81	7
PLK1	75	3
PRAK	41	39
PRK2	102	5
ROCK 2	99	18
RSK1	106	1
RSK2	94	3
S6K1	98	0
SGK1	111	17
SmMLCK	92	1
Src	87	5
SRPK1	96	7
SYK	103	8
TBK1	102	8
VEGFR1	84	1
YES1	98	2

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	91	7
Aurora B	100	3
BRSK2	78	10
BTK	95	3
CAMK1	62	13
CAMKK beta	83	0
CDK2-Cyclin A	81	7
CHK1	120	19
CHK2	101	6
CK1 delta	80	3
CK2	79	10
CSK	97	1
DYRK1A	59	2
DYRK2	111	0
DYRK3	81	7
EF2K	88	22
EPH-A2	113	5
EPH-B3	115	13
ERK1	127	24
ERK2	102	2
ERK8	109	8
FGF-R1	81	7
GSK3 beta	83	12
HIPK2	156	5
IGF-1R	67	59
IKK beta	139	74
IKK epsilon	92	1
IR	103	16
IRR	95	12
JNK1	74	9
JNK2	79	14
Lck	98	7
MAPKAP-K2	84	1
MARK3	91	5
MELK	85	2
MKK1	90	1
MNK1	79	2
MNK2	83	19
MSK1	92	7
MST2	122	4
MST4	83	1
NEK2a	153	0
NEK6	120	20
p38 alpha MAPK	98	2
p38 beta MAPK	94	10
p38 delta MAPK	105	1
p38 gamma MAPK	106	8
PAK4	66	4
PAK5	111	5
PAK6	109	6
PDK1	73	2
PHK	96	9
PIM1	83	5
PIM2	106	2
PIM3	72	2
PKA	86	4
PKB alpha	105	9
PKB beta	103	6
PKC alpha	88	10
PKC zeta	74	3
PKD1	64	1
PLK1	60	5
PRAK	39	5
PRK2	92	5
ROCK 2	91	12
RSK1	113	2
RSK2	88	21
S6K1	105	16
SGK1	109	13
SmMLCK	74	3
Src	70	0
SRPK1	87	2
SYK	85	9
TBK1	88	0
VEGFR1	74	10
YES1	102	3