Inhibitor | Caffeine  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	90	4
Aurora B	91	0
BRSK2	99	7
BTK	79	1
CAMK1	90	6
CAMKK beta	104	3
CDK2-Cyclin A	86	1
CHK1	88	6
CHK2	86	3
CK1 delta	118	10
CK2	115	4
CSK	100	3
DYRK1A	92	7
DYRK2	81	6
DYRK3	96	16
EF2K	88	1
EPH-A2	96	4
EPH-B3	92	6
ERK1	99	10
ERK2	96	1
ERK8	88	16
FGF-R1	118	4
GSK3 beta	102	5
HIPK2	103	6
IGF-1R	86	0
IKK beta	90	5
IKK epsilon	87	9
IR	104	9
IRR	86	8
JNK1	92	13
JNK2	94	1
Lck	88	7
MAPKAP-K2	102	10
MARK3	79	7
MELK	98	3
MKK1	75	27
MNK1	110	2
MNK2	87	4
MSK1	80	6
MST2	97	8
MST4	96	10
NEK2a	107	1
NEK6	79	14
p38 alpha MAPK	88	9
p38 beta MAPK	107	5
p38 delta MAPK	88	1
p38 gamma MAPK	97	7
PAK4	99	6
PAK5	102	5
PAK6	97	4
PDK1	97	7
PHK	113	10
PIM1	90	13
PIM2	113	1
PIM3	99	3
PKA	103	2
PKB alpha	90	0
PKB beta	81	4
PKC alpha	101	6
PKC zeta	95	6
PKD1	92	1
PLK1	92	5
PRAK	96	0
PRK2	89	12
ROCK 2	91	2
RSK1	74	7
RSK2	98	12
S6K1	100	10
SGK1	102	6
SmMLCK	90	1
Src	96	2
SRPK1	93	5
SYK	92	0
TBK1	92	7
VEGFR1	80	14
YES1	85	0

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	98	2
Aurora B	83	3
BRSK2	97	4
BTK	78	4
CAMK1	101	4
CAMKK beta	103	1
CDK2-Cyclin A	91	7
CHK1	96	16
CHK2	83	2
CK1 delta	120	1
CK2	106	8
CSK	103	13
DYRK1A	96	7
DYRK2	87	10
DYRK3	98	1
EF2K	92	5
EPH-A2	102	2
EPH-B3	97	8
ERK1	113	5
ERK2	101	2
ERK8	95	2
FGF-R1	112	15
GSK3 beta	101	10
HIPK2	112	1
IGF-1R	94	3
IKK beta	100	8
IKK epsilon	90	8
IR	98	23
IRR	80	1
JNK1	78	0
JNK2	100	0
Lck	92	2
MAPKAP-K2	89	14
MARK3	79	19
MELK	90	3
MKK1	75	25
MNK1	99	15
MNK2	91	10
MSK1	82	10
MST2	89	19
MST4	97	7
NEK2a	102	11
NEK6	89	4
p38 alpha MAPK	89	2
p38 beta MAPK	104	2
p38 delta MAPK	88	2
p38 gamma MAPK	110	3
PAK4	100	1
PAK5	114	4
PAK6	101	6
PDK1	92	1
PHK	115	12
PIM1	97	8
PIM2	117	21
PIM3	97	6
PKA	96	2
PKB alpha	101	7
PKB beta	84	5
PKC alpha	100	3
PKC zeta	88	4
PKD1	92	18
PLK1	95	12
PRAK	86	0
PRK2	89	26
ROCK 2	93	8
RSK1	78	2
RSK2	79	8
S6K1	98	3
SGK1	121	34
SmMLCK	91	15
Src	88	7
SRPK1	97	6
SYK	86	2
TBK1	96	8
VEGFR1	84	17
YES1	85	4