Inhibitor | MLN120B  

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	92	4
ASK1	104	4
Aurora A	81	0
Aurora B	72	1
BRSK1	86	5
BRSK2	81	5
BTK	70	2
CAMK1	80	3
CAMKK beta	76	3
CDK2-Cyclin A	112	2
CHK1	90	2
CHK2	107	9
CK1 delta	95	1
CK2	118	4
CLK2	54	1
CSK	109	4
DAPK1	37	2
DYRK1A	70	4
DYRK2	80	4
DYRK3	83	6
EF2K	103	1
EPH-A2	92	4
EPH-A4	105	10
EPH-B1	102	4
EPH-B2	101	4
EPH-B3	92	13
EPH-B4	105	11
ERK1	111	2
ERK2	105	5
ERK8	80	4
FGF-R1	100	7
GCK	87	1
GSK3 beta	89	7
HER4	65	1
HIPK1	109	11
HIPK2	71	5
HIPK3	104	2
IGF-1R	97	13
IKK beta	44	1
IKK epsilon	90	0
IR	108	8
IRAK4	80	7
IRR	66	7
JAK2	93	9
JNK1	92	5
JNK2	99	1
JNK3	95	1
Lck	88	5
LKB1	92	2
MAPKAP-K2	95	1
MAPKAP-K3	95	2
MARK1	107	2
MARK2	85	1
MARK3	96	4
MARK4	95	4
MEKK1	95	5
MELK	81	1
MINK1	97	1
MKK1	96	12
MKK2	96	2
MKK6	94	4
MLK1	77	2
MLK3	80	5
MNK1	70	2
MNK2	92	4
MSK1	104	2
MST2	91	1
MST4	115	3
NEK2a	90	10
NEK6	94	5
NUAK1	74	14
p38 alpha MAPK	101	1
p38 beta MAPK	100	7
p38 delta MAPK	90	5
p38 gamma MAPK	94	6
PAK2	96	3
PAK4	94	3
PAK5	99	2
PAK6	90	4
PDK1	81	7
PHK	105	1
PIM1	48	2
PIM2	80	5
PIM3	40	6
PKA	93	12
PKB alpha	105	9
PKB beta	82	7
PKC alpha	99	1
PKC zeta	107	5
PKD1	104	5
PLK1	99	3
PRAK	98	1
PRK2	63	0
RIPK2	42	7
ROCK 2	76	5
RSK1	95	8
RSK2	99	2
S6K1	95	10
SGK1	98	1
SmMLCK	64	7
Src	102	3
SRPK1	101	10
SYK	95	7
TAK1	88	4
TAO1	104	1
TBK1	96	1
TrkA	73	14
TTK	80	3
VEGFR1	74	7
YES1	82	6

Screen Conc: 30.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	74	0
ASK1	99	5
Aurora A	32	3
Aurora B	25	4
BRSK1	35	0
BRSK2	42	3
BTK	37	10
CAMK1	22	1
CAMKK beta	40	3
CDK2-Cyclin A	52	0
CHK1	69	10
CHK2	71	2
CK1 delta	74	7
CK2	106	3
CLK2	15	6
CSK	85	10
DAPK1	16	2
DYRK1A	16	1
DYRK2	26	3
DYRK3	27	3
EF2K	119	1
EPH-A2	71	5
EPH-A4	84	10
EPH-B1	88	3
EPH-B2	76	10
EPH-B3	47	6
EPH-B4	89	1
ERK1	73	1
ERK2	95	9
ERK8	15	0
FGF-R1	41	4
GCK	26	0
GSK3 beta	53	7
HER4	42	11
HIPK1	82	3
HIPK2	49	4
HIPK3	98	2
IGF-1R	54	8
IKK beta	11	0
IKK epsilon	53	2
IR	84	12
IRAK4	41	5
IRR	38	3
JAK2	46	6
JNK1	77	2
JNK2	85	8
JNK3	65	1
Lck	72	5
LKB1	51	4
MAPKAP-K2	78	1
MAPKAP-K3	70	5
MARK1	64	0
MARK2	63	3
MARK3	66	10
MARK4	88	8
MEKK1	74	6
MELK	33	10
MINK1	26	2
MKK1	61	0
MKK2	74	0
MKK6	84	14
MLK1	54	5
MLK3	31	1
MNK1	47	5
MNK2	47	6
MSK1	78	0
MST2	54	1
MST4	125	10
NEK2a	76	8
NEK6	94	14
NUAK1	29	2
p38 alpha MAPK	82	1
p38 beta MAPK	83	4
p38 delta MAPK	62	2
p38 gamma MAPK	44	5
PAK2	79	2
PAK4	69	1
PAK5	64	3
PAK6	92	3
PDK1	79	1
PHK	58	1
PIM1	13	1
PIM2	39	3
PIM3	17	1
PKA	81	4
PKB alpha	60	1
PKB beta	60	1
PKC alpha	75	1
PKC zeta	85	8
PKD1	49	0
PLK1	73	2
PRAK	78	5
PRK2	30	2
RIPK2	24	6
ROCK 2	26	3
RSK1	73	4
RSK2	53	1
S6K1	72	4
SGK1	80	1
SmMLCK	38	7
Src	75	5
SRPK1	86	3
SYK	62	8
TAK1	67	7
TAO1	54	3
TBK1	69	7
TrkA	51	2
TTK	45	3
VEGFR1	20	3
YES1	39	1