Inhibitor | ZM 336372  

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	89	0
Aurora B	87	0
CAMK1	99	2
CDK2-Cyclin A	96	3
CHK1	84	9
CHK2	83	6
CK1 delta	90	2
CK2	100	7
CSK	95	25
DYRK1A	97	7
EF2K	89	1
ERK2	92	1
ERK8	100	6
GSK3 beta	85	12
IKK beta	82	5
JNK1	92	2
JNK3	83	6
Lck	28	0
MAPKAP-K2	89	1
MAPKAP-K3	91	0
MARK3	100	13
MKK1	77	29
MNK1	84	10
MNK2	95	2
MSK1	96	2
MST2	86	3
NEK2a	76	0
NEK6	105	3
NEK7	95	8
p38 alpha MAPK	28	1
p38 beta MAPK	53	15
p38 delta MAPK	92	9
p38 gamma MAPK	86	2
PDK1	95	3
PHK	96	11
PIM2	74	10
PKA	87	3
PKB alpha	105	2
PKB beta	100	13
PKC alpha	95	5
PKD1	81	7
PLK1	97	1
PRAK	91	4
PRK2	87	16
ROCK 2	85	1
RSK1	102	15
RSK2	106	3
S6K1	86	1
SGK1	90	5
SmMLCK	91	5
Src	95	5
SRPK1	94	9

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	82	2
Aurora B	94	2
Aurora C	85	5
BRSK2	78	9
BTK	93	13
CAMK1	77	9
CAMKK alpha	101	2
CAMKK beta	96	1
CDK2-Cyclin A	101	3
CHK1	89	8
CHK2	80	4
CK1 delta	90	3
CK2	92	3
CSK	67	3
DYRK1A	75	6
DYRK2	92	1
DYRK3	90	1
EF2K	105	0
EPH-A2	13	3
EPH-B3	9	0
ERK1	81	1
ERK2	93	2
ERK8	87	1
FGF-R1	105	6
GSK3 beta	107	4
HIPK2	105	8
HIPK3	107	7
IGF-1R	86	5
IKK beta	90	7
IKK epsilon	97	6
IR	94	8
IRR	88	1
JNK1	85	2
JNK2	84	6
JNK3	85	0
Lck	10	0
MAPKAP-K2	89	6
MAPKAP-K3	105	8
MARK3	121	8
MELK	82	8
MKK1	105	0
MNK1	85	0
MNK2	101	8
MSK1	95	1
MST2	84	1
MST4	103	11
NEK2a	85	6
NEK6	90	4
NEK7	97	0
p38 alpha MAPK	7	0
p38 beta MAPK	14	1
p38 delta MAPK	94	8
p38 gamma MAPK	94	0
PAK4	97	3
PAK5	96	1
PAK6	107	1
PDK1	84	2
PHK	120	4
PIM1	95	6
PIM2	92	7
PIM3	80	3
PKA	92	6
PKB alpha	104	1
PKB beta	62	1
PKC alpha	88	4
PKC zeta	77	7
PKD1	104	2
PLK1	95	3
PRAK	61	7
PRK2	91	5
ROCK 2	95	2
RSK1	70	0
RSK2	69	4
S6K1	110	3
SGK1	91	2
SmMLCK	84	7
Src	84	4
SRPK1	86	3
SYK	127	36
TBK1	94	5
VEGFR1	108	8
YES1	77	6