Inhibitor | Wortmannin (KY 12420)  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	88	11
Aurora B	86	4
CAMK1	92	12
CDK2-Cyclin A	100	16
CHK1	87	15
CHK2	87	10
CK1 delta	96	1
CK2	99	5
CSK	97	12
DYRK1A	96	10
EF2K	95	3
ERK2	108	1
ERK8	96	1
GSK3 beta	81	5
IKK beta	83	5
JNK1	81	9
JNK3	81	4
Lck	83	0
MAPKAP-K2	96	14
MAPKAP-K3	96	1
MARK3	104	6
MKK1	83	12
MNK1	85	1
MNK2	90	3
MSK1	101	5
MST2	79	0
NEK2a	88	0
NEK6	107	4
NEK7	99	8
p38 alpha MAPK	95	5
p38 beta MAPK	81	3
p38 delta MAPK	77	2
p38 gamma MAPK	100	19
PDK1	97	8
PHK	103	2
PIM2	69	2
PKA	81	5
PKB alpha	102	0
PKB beta	104	0
PKC alpha	86	5
PKD1	99	8
PLK1	43	1
PRAK	85	4
PRK2	76	4
ROCK 2	84	4
RSK1	95	0
RSK2	106	0
S6K1	70	1
SGK1	114	17
SmMLCK	81	0
Src	84	2
SRPK1	96	18

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	88	3
Aurora B	82	1
Aurora C	69	2
BRSK2	80	4
CAMK1	97	4
CAMKK alpha	82	1
CAMKK beta	70	4
CDK2-Cyclin A	94	9
CHK1	87	7
CHK2	90	2
CK1 delta	94	1
CK2	96	6
CSK	73	8
DYRK1A	87	1
DYRK2	98	1
DYRK3	84	1
EF2K	97	4
ERK1	105	4
ERK2	90	7
ERK8	98	6
GSK3 beta	64	1
HIPK2	94	7
HIPK3	75	1
IKK beta	96	4
JNK1	84	2
JNK2	82	0
JNK3	96	0
Lck	73	4
MAPKAP-K2	125	4
MAPKAP-K3	97	4
MARK3	85	2
MELK	61	1
MKK1	63	0
MNK1	81	2
MNK2	96	0
MSK1	84	0
MST2	96	9
NEK2a	81	1
NEK6	112	6
NEK7	99	6
p38 alpha MAPK	117	8
p38 beta MAPK	97	5
p38 delta MAPK	83	4
p38 gamma MAPK	94	0
PAK4	89	1
PAK5	71	1
PAK6	86	1
PDK1	91	1
PHK	74	1
PIM1	86	3
PIM2	83	4
PIM3	86	0
PKA	86	0
PKB alpha	96	5
PKB beta	89	1
PKC alpha	68	0
PKC zeta	83	0
PKD1	92	2
PLK1	64	1
PRAK	69	1
PRK2	71	2
ROCK 2	98	3
RSK1	86	5
RSK2	90	2
S6K1	94	1
SGK1	85	5
SmMLCK	72	3
Src	82	0
SRPK1	73	3