Inhibitor | SC514 ( IKK-2 Inhibitor)  

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	77	10
Aurora B	50	4
Aurora C	70	2
BRSK2	77	2
CAMK1	87	7
CAMKK alpha	90	4
CAMKK beta	87	1
CDK2-Cyclin A	84	7
CHK1	69	9
CHK2	93	12
CK1 delta	91	12
CK2	75	6
CSK	81	2
DYRK1A	41	1
DYRK2	66	4
DYRK3	47	6
EF2K	113	6
EPH-A2	74	2
ERK1	88	6
ERK2	96	9
ERK8	47	2
FGF-R1	63	10
GSK3 beta	76	2
HIPK2	47	2
HIPK3	77	7
IKK beta	28	1
IKK epsilon	93	1
IRR	63	4
JNK1	89	4
JNK2	93	7
JNK3	94	9
Lck	70	7
MAPKAP-K2	97	3
MAPKAP-K3	92	3
MARK3	64	5
MELK	80	5
MKK1	83	8
MNK1	72	4
MNK2	91	3
MSK1	86	8
MST2	69	6
MST4	114	3
NEK2a	90	5
NEK6	93	9
NEK7	114	1
p38 alpha MAPK	102	9
p38 beta MAPK	99	8
p38 delta MAPK	87	1
p38 gamma MAPK	79	8
PAK4	88	4
PAK5	82	3
PAK6	89	11
PDK1	93	11
PHK	103	8
PIM1	40	6
PIM2	55	2
PIM3	25	4
PKA	85	2
PKB alpha	81	7
PKB beta	103	8
PKC alpha	67	6
PKC zeta	75	10
PKD1	75	2
PLK1	99	7
PRAK	61	6
PRK2	35	1
ROCK 2	59	3
RSK1	97	5
RSK2	90	6
S6K1	84	9
SGK1	105	6
SmMLCK	80	7
Src	90	6
SRPK1	82	3
SYK	90	12
TBK1	95	5
YES1	97	0

Screen Conc: 20.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	92	11
Aurora B	32	4
Aurora C	49	15
BRSK2	74	8
CAMK1	68	5
CAMKK beta	78	3
CDK2-Cyclin A	59	0
CHK1	64	13
CHK2	94	3
CK1 delta	62	4
CK2	54	1
CSK	102	8
DYRK1A	41	3
DYRK2	62	4
DYRK3	40	2
EF2K	86	12
EPH-A2	67	10
ERK1	98	12
ERK2	93	13
ERK8	21	2
FGF-R1	55	11
GSK3 beta	79	5
HIPK2	37	3
IKK beta	17	2
IKK epsilon	108	6
IRR	60	4
JNK1	84	14
JNK2	93	12
JNK3	84	4
Lck	81	6
MAPKAP-K2	60	3
MAPKAP-K3	87	9
MARK3	73	2
MELK	67	5
MKK1	71	0
MNK1	51	5
MNK2	65	12
MSK1	91	5
MST2	79	3
MST4	107	5
NEK2a	83	0
NEK6	82	10
NEK7	101	1
p38 alpha MAPK	80	10
p38 beta MAPK	93	11
p38 delta MAPK	88	7
p38 gamma MAPK	96	15
PAK4	97	4
PAK5	91	4
PAK6	98	12
PDK1	86	14
PHK	83	6
PIM1	25	5
PIM2	46	0
PIM3	12	1
PKA	68	13
PKB alpha	82	3
PKB beta	86	8
PKC alpha	57	12
PKC zeta	97	6
PKD1	46	3
PLK1	113	7
PRAK	57	1
PRK2	28	0
ROCK 2	48	10
RSK1	75	12
RSK2	93	8
S6K1	89	9
SGK1	81	3
SmMLCK	53	6
Src	87	0
SRPK1	78	9
SYK	88	4
TBK1	107	6
YES1	112	11