Inhibitor | SB-415286  

Screen Conc: 2.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	52	8
Aurora B	70	1
Aurora C	89	1
BRSK2	60	1
CAMK1	86	11
CAMKK beta	59	3
CDK2-Cyclin A	62	4
CHK1	83	1
CHK2	60	3
CK1 delta	79	5
CK2	99	1
CSK	113	2
DYRK1A	46	3
DYRK2	107	2
DYRK3	86	6
EF2K	103	6
EPH-A2	88	12
ERK1	82	9
ERK2	78	3
ERK8	16	5
FGF-R1	58	6
GSK3 beta	5	1
HIPK2	87	10
HIPK3	91	9
IKK beta	91	0
IKK epsilon	63	6
IRR	56	11
JNK1	101	9
JNK2	101	13
JNK3	77	3
Lck	83	1
MAPKAP-K2	75	2
MAPKAP-K3	105	0
MARK3	78	11
MELK	82	0
MKK1	58	11
MNK1	78	4
MNK2	105	4
MSK1	87	8
MST2	25	0
MST4	47	1
NEK2a	70	8
NEK6	77	6
NEK7	82	11
p38 alpha MAPK	79	2
p38 beta MAPK	83	9
p38 delta MAPK	93	8
p38 gamma MAPK	94	5
PAK4	88	7
PAK5	95	6
PAK6	97	8
PDK1	83	2
PHK	75	11
PIM1	65	0
PIM2	70	1
PIM3	74	7
PKA	108	9
PKB alpha	92	7
PKB beta	85	2
PKC alpha	78	7
PKC zeta	91	13
PKD1	92	7
PLK1	110	1
PRAK	93	3
PRK2	71	6
ROCK 2	86	8
RSK1	52	3
RSK2	50	4
S6K1	85	1
SGK1	109	7
SmMLCK	63	6
Src	70	6
SRPK1	91	8
SYK	82	6
TBK1	43	4
YES1	79	13

Screen Conc: 10.00µM

Kinase	% Activity Remaining	Standard Deviation
AMPK	33	4
Aurora B	64	3
Aurora C	70	4
BRSK2	38	3
CAMK1	61	3
CAMKK alpha	53	6
CAMKK beta	29	3
CDK2-Cyclin A	18	1
CHK1	60	5
CHK2	69	10
CK1 delta	68	4
CK2	97	1
CSK	89	2
DYRK1A	30	3
DYRK2	83	7
DYRK3	84	5
EF2K	94	2
EPH-A2	90	1
ERK1	94	9
ERK2	95	8
ERK8	13	3
FGF-R1	24	2
GSK3 beta	4	1
HIPK2	63	2
HIPK3	85	6
IKK beta	84	5
IKK epsilon	27	3
IRR	34	0
JNK1	95	1
JNK2	88	4
JNK3	90	6
Lck	66	3
MAPKAP-K2	85	5
MAPKAP-K3	99	6
MARK3	29	2
MELK	72	5
MKK1	28	3
MNK1	77	8
MNK2	91	8
MSK1	62	5
MST2	14	2
MST4	22	2
NEK2a	86	6
NEK6	74	1
NEK7	86	9
p38 alpha MAPK	72	6
p38 beta MAPK	89	7
p38 delta MAPK	82	2
p38 gamma MAPK	98	7
PAK4	52	4
PAK5	67	2
PAK6	74	1
PDK1	62	2
PHK	84	3
PIM1	37	2
PIM2	46	3
PIM3	46	8
PKA	80	8
PKB alpha	92	1
PKB beta	85	10
PKC alpha	39	3
PKC zeta	69	4
PKD1	64	8
PLK1	85	7
PRAK	81	5
PRK2	43	7
ROCK 2	79	4
RSK1	31	2
RSK2	29	1
S6K1	81	2
SGK1	82	6
SmMLCK	65	8
Src	77	7
SRPK1	54	6
SYK	82	1
TBK1	12	1
YES1	72	4