| Compound name | Brutto | MW | CAS | PubChem CID | Action | Reference | Reference |
|---|---|---|---|---|---|---|---|
| Alsterpaullone | C16H11N3O3 | 293.30 | 237430-03-4 | 5005498 | GSK3b, CDK5/p25, CDK1/cyclin B | Leost M. (2000) Eur. J. Biochem. 267 5983 | Schultz C. (1999) J. Med. Chem. 42 2909 |
| Kinase | % Activity Remaining | Standard Deviation |
|---|---|---|
| AMPK | 73 | 6 |
| Aurora B | 78 | 3 |
| Aurora C | 76 | 4 |
| BRSK2 | 37 | 4 |
| CAMK1 | 54 | 2 |
| CAMKK alpha | 80 | 3 |
| CAMKK beta | 68 | 3 |
| CDK2-Cyclin A |
10
|
2 |
| CHK1 | 64 | 4 |
| CHK2 | 13 | 4 |
| CK1 delta | 98 | 4 |
| CK2 | 88 | 1 |
| CSK | 83 | 9 |
| DYRK1A | 83 | 1 |
| DYRK2 | 87 | 3 |
| DYRK3 | 93 | 9 |
| EF2K | 87 | 4 |
| EPH-A2 | 90 | 9 |
| ERK1 | 95 | 0 |
| ERK2 | 79 | 5 |
| ERK8 | 87 | 5 |
| FGF-R1 | 46 | 9 |
| GSK3 beta |
3
|
0 |
| HIPK2 | 77 | 2 |
| HIPK3 | 95 | 1 |
| IKK beta | 90 | 2 |
| IKK epsilon | 66 | 8 |
| IRR | 37 | 5 |
| JNK1 | 82 | 5 |
| JNK2 | 81 | 4 |
| JNK3 | 78 | 0 |
| Lck | 52 | 4 |
| MAPKAP-K2 | 95 | 4 |
| MAPKAP-K3 | 70 | 5 |
| MARK3 | 63 | 5 |
| MELK | 54 | 2 |
| MKK1 | 86 | 3 |
| MNK1 | 74 | 1 |
| MNK2 | 90 | 4 |
| MSK1 | 82 | 6 |
| MST2 | 53 | 3 |
| MST4 | 78 | 1 |
| NEK2a | 92 | 2 |
| NEK6 | 86 | 1 |
| NEK7 | 92 | 5 |
| p38 alpha MAPK | 109 | 1 |
| p38 beta MAPK | 86 | 2 |
| p38 delta MAPK | 86 | 0 |
| p38 gamma MAPK | 87 | 5 |
| PAK4 | 33 | 0 |
| PAK5 | 40 | 5 |
| PAK6 | 64 | 9 |
| PDK1 | 71 | 5 |
| PHK | 11 | 1 |
| PIM1 | 81 | 5 |
| PIM2 | 91 | 5 |
| PIM3 | 78 | 8 |
| PKA | 79 | 1 |
| PKB alpha | 88 | 1 |
| PKB beta | 88 | 1 |
| PKC alpha | 80 | 7 |
| PKC zeta | 50 | 4 |
| PKD1 | 91 | 9 |
| PLK1 | 81 | 5 |
| PRAK | 76 | 0 |
| PRK2 | 61 | 6 |
| ROCK 2 | 87 | 4 |
| RSK1 | 67 | 3 |
| RSK2 | 73 | 7 |
| S6K1 | 93 | 1 |
| SGK1 | 85 | 1 |
| SmMLCK | 91 | 4 |
| Src | 61 | 2 |
| SRPK1 | 79 | 7 |
| SYK | 31 | 6 |
| TBK1 | 35 | 2 |
| YES1 | 22 | 1 |