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Compound name | Brutto | MW | CAS | PubChem CID | Action | Reference | Reference |
---|---|---|---|---|---|---|---|
Akti 1/2 | C34H29N7O | 551.60 | 612847-09-3 | 10196499 | Akt1, Akt2 | Logie L. (2007) Diabetes 2218-27 | Barnett S.F. (2005) Biochem. J. 385 399 |
Kinase Sort descending | % Activity Remaining | Standard Deviation |
---|---|---|
AMPK | 92 | 10 |
Aurora B | 60 | 3 |
Aurora C | 65 | 0 |
BRSK2 | 92 | 12 |
CAMK1 |
3
|
0 |
CAMKK alpha | 62 | 3 |
CAMKK beta | 108 | 9 |
CDK2-Cyclin A | 97 | 13 |
CHK1 | 85 | 2 |
CHK2 | 82 | 7 |
CK1 delta | 110 | 2 |
CK2 | 91 | 14 |
CSK | 103 | 15 |
DYRK1A | 93 | 12 |
DYRK2 | 118 | 1 |
DYRK3 | 74 | 1 |
EF2K | 40 | 6 |
EPH-A2 | 84 | 7 |
ERK1 | 99 | 5 |
ERK2 | 75 | 14 |
ERK8 | 70 | 1 |
FGF-R1 | 75 | 3 |
GSK3 beta | 77 | 9 |
HIPK2 | 84 | 3 |
HIPK3 | 65 | 2 |
IKK beta | 89 | 2 |
IKK epsilon | 67 | 6 |
IRR | 81 | 13 |
JNK1 | 70 | 9 |
JNK2 | 81 | 12 |
JNK3 | 80 | 7 |
Lck | 64 | 6 |
MAPKAP-K2 | 59 | 1 |
MAPKAP-K3 | 71 | 5 |
MARK3 | 95 | 12 |
MELK | 67 | 0 |
MKK1 | 76 | 10 |
MNK1 | 84 | 1 |
MNK2 | 79 | 3 |
MSK1 | 93 | 14 |
MST2 | 78 | 2 |
MST4 | 80 | 4 |
NEK2a | 99 | 3 |
NEK6 | 75 | 3 |
NEK7 | 84 | 10 |
p38 alpha MAPK | 98 | 13 |
p38 beta MAPK | 113 | 3 |
p38 delta MAPK | 98 | 11 |
p38 gamma MAPK | 93 | 9 |
PAK4 | 48 | 4 |
PAK5 | 60 | 3 |
PAK6 | 92 | 1 |
PDK1 | 94 | 7 |
PHK | 101 | 9 |
PIM1 | 56 | 6 |
PIM2 | 89 | 3 |
PIM3 | 59 | 6 |
PKA | 76 | 5 |
PKB alpha | 64 | 8 |
PKB beta | 87 | 14 |
PKC alpha | 87 | 8 |
PKC zeta | 96 | 9 |
PKD1 | 82 | 14 |
PLK1 | 89 | 2 |
PRAK | 79 | 5 |
PRK2 | 67 | 10 |
ROCK 2 | 91 | 1 |
RSK1 | 67 | 1 |
RSK2 | 74 | 1 |
S6K1 | 71 | 6 |
SGK1 | 82 | 3 |
SmMLCK | 11 | 4 |
Src | 118 | 1 |
SRPK1 | 84 | 9 |
SYK | 84 | 10 |
TBK1 | 106 | 10 |
YES1 | 88 | 8 |
Kinase Sort descending | % Activity Remaining | Standard Deviation |
---|---|---|
AMPK | 87 | 6 |
ASK1 | 109 | 3 |
Aurora A | 94 | 4 |
Aurora B | 100 | 10 |
BRSK1 | 94 | 4 |
BRSK2 | 95 | 5 |
BTK | 75 | 2 |
CAMK1 | 44 | 7 |
CAMKK beta | 104 | 1 |
CDK2-Cyclin A | 108 | 14 |
CHK1 | 98 | 10 |
CHK2 | 89 | 11 |
CK1 delta | 94 | 0 |
CK2 | 111 | 0 |
CLK2 | 96 | 10 |
CSK | 102 | 2 |
DAPK1 | 91 | 4 |
DYRK1A | 84 | 2 |
DYRK2 | 88 | 5 |
DYRK3 | 91 | 11 |
EF2K | 61 | 6 |
EPH-A2 | 103 | 6 |
EPH-A4 | 101 | 1 |
EPH-B1 | 100 | 8 |
EPH-B2 | 100 | 8 |
EPH-B3 | 96 | 14 |
EPH-B4 | 95 | 13 |
ERK1 | 92 | 8 |
ERK2 | 103 | 4 |
ERK8 | 87 | 4 |
FGF-R1 | 80 | 7 |
GCK | 89 | 2 |
GSK3 beta | 103 | 1 |
HER4 | 95 | 4 |
HIPK1 | 77 | 2 |
HIPK2 | 81 | 4 |
HIPK3 | 95 | 8 |
IGF-1R | 96 | 0 |
IKK beta | 93 | 8 |
IKK epsilon | 76 | 3 |
IR | 109 | 3 |
IRAK4 | 93 | 6 |
IRR | 94 | 3 |
JAK2 | 103 | 2 |
JNK1 | 90 | 2 |
JNK2 | 92 | 11 |
JNK3 | 104 | 9 |
Lck | 90 | 4 |
LKB1 | 89 | 0 |
MAPKAP-K2 | 91 | 3 |
MAPKAP-K3 | 88 | 2 |
MARK1 | 79 | 1 |
MARK2 | 93 | 3 |
MARK3 | 98 | 5 |
MARK4 | 103 | 3 |
MEKK1 | 98 | 2 |
MELK | 79 | 2 |
MINK1 | 54 | 9 |
MKK1 | 84 | 12 |
MKK2 | 101 | 3 |
MKK6 | 101 | 11 |
MLK1 | 73 | 0 |
MLK3 | 89 | 4 |
MNK1 | 110 | 2 |
MNK2 | 100 | 2 |
MSK1 | 94 | 4 |
MST2 | 66 | 1 |
MST4 | 83 | 2 |
NEK2a | 90 | 3 |
NEK6 | 117 | 8 |
NUAK1 | 71 | 0 |
p38 alpha MAPK | 82 | 1 |
p38 beta MAPK | 108 | 9 |
p38 delta MAPK | 88 | 8 |
p38 gamma MAPK | 97 | 3 |
PAK2 | 92 | 8 |
PAK4 | 68 | 9 |
PAK5 | 63 | 1 |
PAK6 | 109 | 8 |
PDK1 | 108 | 4 |
PHK | 102 | 11 |
PIM1 | 80 | 0 |
PIM2 | 86 | 1 |
PIM3 | 63 | 1 |
PKA | 100 | 10 |
PKB alpha | 95 | 4 |
PKB beta | 65 | 7 |
PKC alpha | 82 | 3 |
PKC zeta | 113 | 4 |
PKD1 | 86 | 7 |
PLK1 | 98 | 4 |
PRAK | 92 | 5 |
PRK2 | 79 | 7 |
RIPK2 | 57 | 3 |
ROCK 2 | 82 | 10 |
RSK1 | 97 | 4 |
RSK2 | 74 | 1 |
S6K1 | 106 | 8 |
SGK1 | 98 | 4 |
SmMLCK | 82 | 13 |
Src | 105 | 9 |
SRPK1 | 84 | 7 |
SYK | 89 | 7 |
TAK1 | 78 | 8 |
TAO1 | 87 | 4 |
TBK1 | 88 | 4 |
TrkA | 76 | 7 |
TTK | 92 | 3 |
VEGFR1 | 71 | 3 |
YES1 | 79 | 6 |
Kinase Sort descending | % Activity Remaining | Standard Deviation |
---|---|---|
AMPK | 96 | 14 |
Aurora B | 83 | 5 |
Aurora C | 83 | 0 |
BRSK2 | 93 | 0 |
CAMK1 | 90 | 3 |
CDK2-Cyclin A | 92 | 3 |
CHK1 | 97 | 0 |
CHK2 | 83 | 7 |
CK1 delta | 106 | 7 |
CK2 | 85 | 1 |
CSK | 97 | 11 |
DYRK1A | 97 | 11 |
DYRK2 | 105 | 3 |
DYRK3 | 87 | 6 |
EF2K | 107 | 11 |
EPH-A2 | 95 | 6 |
ERK1 | 95 | 3 |
ERK2 | 71 | 15 |
ERK8 | 80 | 5 |
FGF-R1 | 89 | 8 |
GSK3 beta | 83 | 3 |
HIPK2 | 98 | 6 |
HIPK3 | 72 | 2 |
IKK beta | 91 | 11 |
IKK epsilon | 107 | 7 |
IRR | 91 | 3 |
JNK1 | 85 | 0 |
JNK2 | 95 | 0 |
JNK3 | 79 | 3 |
Lck | 81 | 4 |
MAPKAP-K2 | 84 | 6 |
MAPKAP-K3 | 76 | 3 |
MARK3 | 86 | 1 |
MELK | 86 | 10 |
MKK1 | 75 | 2 |
MNK1 | 81 | 0 |
MNK2 | 93 | 11 |
MSK1 | 84 | 2 |
MST2 | 103 | 0 |
MST4 | 92 | 1 |
NEK2a | 92 | 6 |
NEK6 | 83 | 1 |
NEK7 | 86 | 0 |
p38 alpha MAPK | 111 | 5 |
p38 beta MAPK | 103 | 10 |
p38 delta MAPK | 104 | 5 |
p38 gamma MAPK | 110 | 7 |
PAK4 | 99 | 4 |
PAK5 | 87 | 7 |
PAK6 | 112 | 8 |
PDK1 | 91 | 9 |
PHK | 104 | 1 |
PIM1 | 83 | 12 |
PIM2 | 95 | 6 |
PIM3 | 97 | 5 |
PKA | 90 | 8 |
PKB alpha | 85 | 3 |
PKB beta | 101 | 6 |
PKC alpha | 101 | 5 |
PKC zeta | 101 | 0 |
PKD1 | 90 | 4 |
PLK1 | 83 | 2 |
PRAK | 93 | 5 |
PRK2 | 78 | 1 |
ROCK 2 | 92 | 7 |
RSK1 | 94 | 4 |
RSK2 | 85 | 7 |
S6K1 | 98 | 1 |
SGK1 | 106 | 5 |
SmMLCK | 86 | 7 |
Src | 97 | 3 |
SRPK1 | 87 | 1 |
SYK | 83 | 2 |
TBK1 | 103 | 11 |
YES1 | 86 | 4 |
Kinase Sort descending | % Activity Remaining | Standard Deviation |
---|---|---|
AMPK | 97 | 0 |
Aurora B | 56 | 11 |
Aurora C | 70 | 15 |
BRSK2 | 76 | 9 |
CAMK1 |
8
|
0 |
CDK2-Cyclin A | 93 | 3 |
CHK1 | 88 | 5 |
CHK2 | 58 | 3 |
CK1 delta | 88 | 5 |
CK2 | 84 | 7 |
CSK | 92 | 0 |
DYRK1A | 99 | 5 |
DYRK2 | 106 | 0 |
DYRK3 | 60 | 4 |
EF2K | 43 | 1 |
EPH-A2 | 69 | 1 |
ERK1 | 87 | 2 |
ERK2 | 45 | 1 |
ERK8 | 51 | 1 |
FGF-R1 | 55 | 0 |
GSK3 beta | 43 | 9 |
HIPK2 | 61 | 1 |
HIPK3 | 68 | 2 |
IKK beta | 98 | 2 |
IKK epsilon | 100 | 1 |
IRR | 68 | 1 |
JNK1 | 48 | 1 |
JNK2 | 80 | 7 |
JNK3 | 42 | 1 |
Lck | 31 | 3 |
MAPKAP-K2 | 12 | 0 |
MAPKAP-K3 | 52 | 2 |
MARK3 | 90 | 8 |
MELK | 45 | 5 |
MKK1 | 14 | 3 |
MNK1 | 82 | 0 |
MNK2 | 77 | 10 |
MSK1 | 41 | 1 |
MST2 | 83 | 7 |
MST4 | 92 | 6 |
NEK2a | 70 | 2 |
NEK6 | 44 | 1 |
NEK7 | 15 | 0 |
p38 alpha MAPK | 83 | 2 |
p38 beta MAPK | 86 | 15 |
p38 delta MAPK | 89 | 3 |
p38 gamma MAPK | 87 | 0 |
PAK4 | 33 | 1 |
PAK5 | 63 | 5 |
PAK6 | 66 | 1 |
PDK1 | 98 | 15 |
PHK | 59 | 2 |
PIM1 | 17 | 1 |
PIM2 | 23 | 0 |
PIM3 | 16 | 1 |
PKA | 39 | 0 |
PKB alpha |
6
|
0 |
PKB beta | 26 | 2 |
PKC alpha | 96 | 3 |
PKC zeta | 104 | 8 |
PKD1 | 81 | 3 |
PLK1 | 83 | 2 |
PRAK | 51 | 4 |
PRK2 | 59 | 2 |
ROCK 2 | 92 | 9 |
RSK1 | 36 | 1 |
RSK2 | 22 | 1 |
S6K1 | 34 | 11 |
SGK1 | 14 | 5 |
SmMLCK |
-1
|
0 |
Src | 62 | 5 |
SRPK1 | 67 | 0 |
SYK | 44 | 2 |
TBK1 | 100 | 4 |
YES1 | 61 | 2 |