Inhibitor | Purvalanol B  

Screen Conc: 0.10µM

Kinase	% Activity Remaining	Standard Deviation
ABL	85	5
AMPK	107	1
ASK1	94	1
Aurora A	95	0
Aurora B	93	3
BRK	122	10
BRSK1	91	7
BRSK2	103	0
BTK	63	2
CAMK1	91	8
CAMKK beta	86	1
CDK2-Cyclin A	5	0
CHK1	116	14
CHK2	98	0
CK1 delta	107	14
CK2	101	15
CLK2	16	4
CSK	96	3
DAPK1	106	5
DYRK1A	65	1
DYRK2	113	0
DYRK3	96	10
EF2K	89	15
EPH-A2	80	8
EPH-A4	61	10
EPH-B1	111	2
EPH-B2	83	12
EPH-B3	78	4
EPH-B4	107	0
ERK1	102	3
ERK2	100	9
ERK8	43	9
FGF-R1	85	5
GCK	92	12
GSK3 beta	91	6
HER4	102	1
HIPK1	97	12
HIPK2	95	6
HIPK3	111	6
IGF-1R	85	14
IKK beta	102	1
IKK epsilon	108	7
IR	99	11
IRAK4	77	1
IRR	68	11
JAK2	103	3
JNK1	97	2
JNK2	119	0
JNK3	116	9
Lck	107	8
LKB1	88	6
MAPKAP-K2	89	4
MAPKAP-K3	95	13
MARK1	115	0
MARK2	109	7
MARK3	112	1
MARK4	115	7
MEKK1	62	0
MELK	90	4
MINK1	101	13
MKK1	104	11
MKK2	74	8
MKK6	94	3
MLK1	40	4
MLK3	55	1
MNK1	88	10
MNK2	85	11
MPSK1	109	1
MSK1	100	2
MST2	104	15
MST4	87	3
NEK2a	99	0
NEK6	92	5
NUAK1	99	12
p38 alpha MAPK	94	1
p38 beta MAPK	117	6
p38 delta MAPK	111	6
p38 gamma MAPK	106	5
PAK2	108	5
PAK4	68	4
PAK5	82	2
PAK6	112	2
PDK1	108	3
PHK	109	3
PIM1	96	2
PIM2	111	3
PIM3	45	14
PKA	111	6
PKB alpha	105	3
PKB beta	109	9
PKC alpha	89	0
PKC gamma	98	4
PKC zeta	113	14
PKD1	101	0
PLK1	106	3
PRAK	106	2
PRK2	90	6
RIPK2	103	6
ROCK 2	97	2
RSK1	93	11
RSK2	82	12
S6K1	102	6
SGK1	105	2
SmMLCK	113	11
Src	17	3
SRPK1	71	9
STK33	95	14
SYK	93	7
TAK1	57	0
TAO1	120	1
TBK1	94	12
TIE2	105	11
TrkA	23	3
TTK	68	5
VEGFR1	90	10
YES1	37	2
ZAP70	74	0

Screen Conc: 1.00µM

Kinase	% Activity Remaining	Standard Deviation
ABL	33	5
AMPK	74	2
ASK1	113	10
Aurora A	49	4
Aurora B	84	9
BRK	91	3
BRSK1	57	0
BRSK2	109	1
BTK	29	6
CAMK1	91	1
CAMKK beta	32	3
CDK2-Cyclin A	2	0
CHK1	87	1
CHK2	40	3
CK1 delta	58	5
CK2	62	5
CLK2	4	3
CSK	75	9
DAPK1	89	6
DYRK1A	13	1
DYRK2	83	0
DYRK3	92	3
EF2K	88	8
EPH-A2	44	9
EPH-A4	30	0
EPH-B1	75	14
EPH-B2	36	0
EPH-B3	45	3
EPH-B4	41	11
ERK1	61	3
ERK2	36	4
ERK8	6	0
FGF-R1	56	5
GCK	48	6
GSK3 beta	62	2
HER4	89	9
HIPK1	78	8
HIPK2	54	9
HIPK3	98	4
IGF-1R	20	1
IKK beta	91	1
IKK epsilon	74	8
IR	6	2
IRAK4	16	1
IRR	30	1
JAK2	51	3
JNK1	75	4
JNK2	90	7
JNK3	92	3
Lck	42	5
LKB1	44	2
MAPKAP-K2	94	15
MAPKAP-K3	101	2
MARK1	78	6
MARK2	94	1
MARK3	58	1
MARK4	65	12
MEKK1	37	12
MELK	61	3
MINK1	72	1
MKK1	72	10
MKK2	51	1
MKK6	96	14
MLK1	4	0
MLK3	8	1
MNK1	93	14
MNK2	99	4
MPSK1	86	10
MSK1	95	3
MST2	60	0
MST4	38	5
NEK2a	72	9
NEK6	86	3
NUAK1	60	4
p38 alpha MAPK	88	9
p38 beta MAPK	102	3
p38 delta MAPK	86	4
p38 gamma MAPK	89	15
PAK2	96	1
PAK4	18	2
PAK5	31	2
PAK6	79	4
PDK1	79	15
PHK	82	0
PIM1	69	2
PIM2	97	3
PIM3	10	0
PKA	64	4
PKB alpha	105	14
PKB beta	82	15
PKC alpha	86	12
PKC gamma	95	2
PKC zeta	93	1
PKD1	92	13
PLK1	69	6
PRAK	74	11
PRK2	71	7
RIPK2	96	13
ROCK 2	109	11
RSK1	38	2
RSK2	57	2
S6K1	93	2
SGK1	91	12
SmMLCK	65	4
Src	3	1
SRPK1	14	0
STK33	36	0
SYK	77	8
TAK1	16	3
TAO1	76	12
TBK1	89	1
TIE2	92	2
TrkA	9	2
TTK	30	7
VEGFR1	43	1
YES1	11	1
ZAP70	108	1