Inhibitor | IKK Inhibitor VII  

Compound name Brutto MW CAS PubChem CID Action Reference Reference
IKK Inhibitor VII   C28H29N5OS 483.60 873225-46-8 9549298 IKK Waelchli R. (2006) Bioorg. Med. Chem. Lett. 16 108

Screening Results Chart

Screening Results Tables

Screen Conc: 10.00µM
Kinase % Activity Remaining Standard Deviation
ERK8
1
 0
JAK2
1
 0
TAK1
2
 1
CDK2-Cyclin A
3
 1
IKK beta
3
 0
IR
3
 1
Aurora A
3
 1
DYRK2
3
 1
CLK2
3
 0
IGF-1R
3
 1
Lck
3
 1
EPH-B1
4
 1
SGK1
4
 1
DAPK1
4
 0
MLK3
5
 0
ROCK 2
5
 1
IKK epsilon
6
 1
EPH-B3
6
 1
PRK2
6
 1
GSK3 beta
6
 1
HIPK1
8
 0
HIPK2
8
 3
CAMK1
8
 2
EPH-B2
8
 0
RIPK2
9
 1
CHK1
10
 1
DYRK3
10
 0
MINK1
10
 3
HIPK3 11 2
SYK 11 1
VEGFR1 11 1
EPH-B4 11 2
GCK 12 0
TrkA 14 2
PHK 14 1
JNK1 14 0
Src 14 6
MARK3 16 1
BTK 16 2
EPH-A4 16 0
TBK1 17 5
Aurora B 17 4
PKD1 18 3
NUAK1 19 3
YES1 19 4
MKK1 19 2
FGF-R1 20 8
p38 beta MAPK 20 7
AMPK 22 4
RSK1 24 1
DYRK1A 24 1
PIM3 24 1
TAO1 25 5
BRSK2 25 1
PKC alpha 26 4
PAK5 27 0
IRR 27 8
PIM1 27 1
MNK1 27 2
CSK 28 2
S6K1 29 2
CK2 30 4
MST2 30 2
EPH-A2 30 4
ASK1 32 6
MARK4 32 2
TTK 33 1
MARK1 33 4
MLK1 34 4
JNK3 35 5
PAK4 36 5
HER4 37 8
MNK2 37 4
JNK2 37 2
IRAK4 38 5
PAK2 38 6
PRAK 38 1
RSK2 39 1
SmMLCK 41 3
MKK2 42 3
MSK1 43 1
BRSK1 43 0
PKB beta 44 6
CAMKK beta 46 5
PKB alpha 47 1
ERK2 51 0
NEK2a 54 1
EF2K 55 7
MELK 58 10
PLK1 60 10
PDK1 61 0
p38 delta MAPK 61 11
CHK2 62 0
ERK1 64 9
PKA 67 8
MEKK1 68 4
MARK2 68 6
p38 gamma MAPK 69 7
MKK6 71 6
MAPKAP-K3 71 5
CK1 delta 72 1
NEK6 76 7
LKB1 77 3
PKC zeta 81 6
p38 alpha MAPK 81 2
PAK6 85 7
SRPK1 90 2
PIM2 91 6
MAPKAP-K2 93 6
MST4 156 6
Screen Conc: 1.00µM
Kinase % Activity Remaining Standard Deviation
JAK2
2
 1
ERK8
6
 2
IKK beta
6
 1
DAPK1
6
 2
MLK3
7
 0
CDK2-Cyclin A 12 1
HIPK2 12 2
TAK1 13 2
VEGFR1 15 2
CLK2 15 1
IKK epsilon 15 3
DYRK2 16 2
Lck 16 1
Aurora A 17 2
TrkA 18 2
IR 20 3
TBK1 23 2
GSK3 beta 24 3
SGK1 24 2
YES1 25 4
NUAK1 26 1
EPH-B1 26 2
EPH-B3 26 0
PRK2 27 3
ROCK 2 29 0
MLK1 30 1
SYK 30 2
PKD1 32 0
RIPK2 34 3
MINK1 35 3
HIPK1 35 2
EPH-B2 35 2
Src 36 4
EPH-B4 37 3
IGF-1R 37 6
DYRK3 37 2
GCK 39 2
JNK3 41 5
EPH-A2 42 2
MARK4 42 12
MNK1 43 6
FGF-R1 44 4
EPH-A4 45 2
MNK2 45 4
BTK 47 2
MARK3 47 0
CAMK1 48 5
HIPK3 49 4
AMPK 49 0
BRSK1 50 5
JNK1 51 3
BRSK2 52 3
Aurora B 52 2
MARK1 52 0
IRR 54 6
TTK 57 4
TAO1 57 2
PHK 57 5
HER4 57 10
CHK1 57 2
MKK1 60 0
CSK 60 4
PIM3 64 1
PAK5 64 3
p38 beta MAPK 65 4
PAK4 65 2
CK2 66 1
PKB alpha 67 3
ERK1 69 8
CAMKK beta 69 6
S6K1 69 7
DYRK1A 70 3
PAK2 71 11
PKC alpha 71 2
PRAK 72 2
MSK1 72 12
PKB beta 73 7
JNK2 74 7
MST2 74 8
RSK1 75 12
MARK2 75 2
p38 delta MAPK 77 3
EF2K 77 0
PAK6 77 5
ERK2 78 1
PIM1 78 5
MEKK1 79 2
IRAK4 79 8
PKA 80 1
LKB1 80 12
ASK1 80 1
PDK1 82 5
RSK2 83 0
PLK1 84 1
MKK2 85 7
NEK6 85 0
p38 gamma MAPK 86 4
SmMLCK 87 1
NEK2a 88 0
CK1 delta 89 0
p38 alpha MAPK 91 12
SRPK1 92 7
MKK6 94 5
PIM2 95 2
MAPKAP-K2 96 3
PKC zeta 98 6
CHK2 98 0
MAPKAP-K3 100 3
MELK 105 3
MST4 143 2