Inhibitor | BAY-11-7082  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
RSK2	8	0
PKB beta	8	1
Aurora A	14	0
CAMK1	19	2
NUAK1	20	1
MINK1	27	4
IKK epsilon	35	1
VEGFR1	40	9
BRSK2	41	7
MST2	51	5
MARK4	58	3
BTK	58	6
MST4	61	6
GCK	67	6
HER4	68	2
MARK2	70	1
PRK2	70	5
PIM1	71	3
PKD1	72	5
BRSK1	73	6
DAPK1	73	6
TBK1	75	6
EPH-A2	75	7
LKB1	75	4
PKC alpha	75	0
MAPKAP-K3	75	0
PRAK	76	3
AMPK	76	4
DYRK2	78	5
SYK	78	1
MLK1	78	2
JNK2	78	5
ERK2	79	2
MSK1	79	5
CHK1	79	2
PAK6	80	7
RIPK2	80	0
TAO1	81	3
ROCK 2	82	7
PIM3	82	1
HIPK1	82	4
PAK2	83	5
PIM2	83	7
JNK3	83	0
S6K1	84	2
JAK2	84	3
SmMLCK	85	9
EF2K	85	4
MKK6	85	1
RSK1	86	1
TTK	86	3
CHK2	86	0
DYRK1A	86	3
CDK2-Cyclin A	87	8
p38 beta MAPK	87	4
IKK beta	87	2
EPH-B4	87	5
IRR	87	3
TrkA	87	7
p38 alpha MAPK	88	7
NEK2a	88	10
HIPK3	88	7
PAK5	89	8
PKA	89	6
MNK1	89	1
MELK	89	13
MKK2	89	7
PDK1	90	4
PKB alpha	90	4
SRPK1	90	2
PKC zeta	92	2
NEK6	92	1
CSK	92	10
FGF-R1	92	11
MKK1	92	11
MAPKAP-K2	92	0
IRAK4	92	2
PLK1	93	5
p38 delta MAPK	93	1
MLK3	93	8
EPH-B1	94	3
MEKK1	94	6
PAK4	95	10
EPH-A4	95	4
MARK3	95	7
IGF-1R	95	2
DYRK3	96	3
MNK2	96	11
HIPK2	96	5
CLK2	96	6
EPH-B3	97	6
p38 gamma MAPK	97	6
CK1 delta	97	6
CAMKK beta	99	1
JNK1	99	1
TAK1	99	6
SGK1	99	6
MARK1	100	1
GSK3 beta	101	3
Aurora B	101	14
ASK1	101	5
ERK8	101	6
ERK1	102	8
CK2	104	4
IR	105	10
PHK	106	5
Lck	107	4
EPH-B2	112	4
YES1	158	14
Src	162	6

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
CAMK1	59	13
PIM3	74	6
IGF-1R	77	40
RSK2	79	2
VEGFR1	80	1
MARK2	80	11
BRSK1	80	11
p38 beta MAPK	81	15
BTK	81	3
Aurora B	82	12
PKD1	83	1
PAK4	83	10
ERK2	84	5
CDK2-Cyclin A	84	4
JNK2	85	3
PKB beta	86	15
MLK1	86	13
PAK6	87	4
MEKK1	88	2
SGK1	88	10
MST4	89	6
MAPKAP-K3	89	8
MST2	90	16
FGF-R1	90	5
MARK3	90	3
HIPK3	90	3
PKA	91	0
PDK1	91	4
JNK1	91	7
PHK	91	3
EPH-B3	92	1
LKB1	93	1
MLK3	93	7
NUAK1	93	5
GSK3 beta	93	6
MAPKAP-K2	93	7
SYK	94	3
AMPK	94	5
TBK1	94	1
MSK1	95	6
IRAK4	95	1
p38 delta MAPK	95	8
MARK4	95	1
MNK2	95	3
PKC alpha	95	6
ROCK 2	96	7
DYRK1A	96	16
DYRK2	96	0
PAK2	96	15
HIPK2	97	4
PAK5	97	7
EPH-A2	98	6
PRAK	98	13
CSK	98	2
RSK1	98	11
IRR	99	1
CHK2	99	6
IR	99	7
JAK2	99	9
NEK6	100	12
p38 alpha MAPK	100	13
PKC zeta	100	10
S6K1	100	16
PRK2	100	0
MELK	101	6
IKK beta	101	10
CK1 delta	101	3
EPH-B2	101	8
PKB alpha	102	4
CAMKK beta	102	6
IKK epsilon	103	1
GCK	103	1
MINK1	103	3
PIM2	103	9
CK2	103	2
EF2K	103	13
CLK2	103	1
Aurora A	103	14
PIM1	104	5
MARK1	104	2
SmMLCK	104	13
NEK2a	104	0
MKK1	105	8
EPH-A4	106	1
BRSK2	106	4
DAPK1	107	13
SRPK1	107	6
JNK3	107	20
TTK	107	14
Lck	108	10
TAK1	108	24
HIPK1	108	18
PLK1	108	1
DYRK3	108	3
RIPK2	109	1
ERK8	110	7
p38 gamma MAPK	112	9
CHK1	113	18
HER4	117	11
MNK1	117	16
ERK1	121	5
TrkA	124	5
EPH-B4	125	4
YES1	127	34
Src	177	4