Inhibitor | AS601245 (JNK Inhibitor V)  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
GSK3 beta	1	1
PIM3	2	0
DYRK2	4	3
PIM1	5	3
HIPK2	7	1
PIM2	7	2
DYRK1A	9	2
DYRK3	9	5
ERK8	12	2
IRR	16	1
HIPK3	18	2
CK2	22	3
p38 delta MAPK	28	2
JNK2	29	3
PKB alpha	32	3
ROCK 2	32	7
PAK4	38	3
Src	38	3
MNK2	39	4
JNK3	40	4
PKD1	40	11
RSK1	40	1
CAMKK beta	41	4
JNK1	43	4
PLK1	43	6
p38 gamma MAPK	46	4
Aurora C	48	7
FGF-R1	49	3
MNK1	50	8
MARK3	50	7
CK1 delta	51	6
PKB beta	51	5
MKK1	51	6
RSK2	52	6
PAK5	54	3
MAPKAP-K2	54	3
YES1	57	8
SmMLCK	57	5
Aurora B	57	5
PRK2	58	8
PHK	62	6
CDK2-Cyclin A	62	5
NEK6	63	10
p38 alpha MAPK	63	1
CHK2	64	5
S6K1	65	8
MELK	66	7
PRAK	67	3
CAMKK alpha	67	8
TBK1	67	2
ERK2	68	4
Lck	68	7
SGK1	69	5
MSK1	69	5
NEK7	70	5
AMPK	70	4
SRPK1	72	1
BRSK2	73	6
PKA	77	8
CSK	77	6
IKK epsilon	78	6
PKC alpha	80	7
NEK2a	81	6
PKC zeta	85	12
IKK beta	86	3
MST2	86	3
p38 beta MAPK	87	8
PAK6	89	11
EF2K	90	5
PDK1	92	9
SYK	92	11
CHK1	95	9
MAPKAP-K3	96	5
ERK1	97	3
MST4	105	3
CAMK1	106	7
EPH-A2	108	11

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
GSK3 beta	2	1
PIM3	3	1
PIM1	8	1
DYRK2	12	1
DYRK3	24	3
HIPK2	29	3
DYRK1A	33	3
PIM2	40	5
ERK8	48	3
HIPK3	61	4
CK2	63	6
p38 delta MAPK	68	10
MNK1	68	10
Aurora C	70	6
MNK2	70	6
RSK1	71	6
CK1 delta	71	7
JNK3	72	5
p38 alpha MAPK	72	8
MKK1	73	6
JNK2	73	5
IRR	74	0
PKB alpha	78	4
p38 gamma MAPK	78	8
IKK epsilon	79	1
Src	79	4
MST2	80	4
ROCK 2	80	3
AMPK	82	7
JNK1	82	9
NEK2a	83	10
Lck	83	5
PAK4	84	11
NEK6	84	9
Aurora B	84	7
MAPKAP-K2	85	7
PHK	85	3
NEK7	85	7
MARK3	86	9
PAK5	86	11
PKC zeta	86	4
CDK2-Cyclin A	86	6
TBK1	87	3
PRK2	88	12
RSK2	89	8
PKC alpha	89	6
MSK1	89	12
CAMKK alpha	90	11
SmMLCK	90	8
EPH-A2	90	14
CAMKK beta	91	7
ERK2	91	9
BRSK2	92	7
MELK	92	3
SGK1	92	3
SYK	93	14
IKK beta	94	6
PKB beta	95	7
CHK2	95	4
SRPK1	96	7
S6K1	96	4
p38 beta MAPK	96	5
PRAK	97	8
CHK1	97	1
CSK	98	4
YES1	99	13
CAMK1	101	2
MST4	101	13
PDK1	102	6
PAK6	102	3
ERK1	104	5
MAPKAP-K3	105	8
PLK1	106	7
PKD1	108	10
FGF-R1	109	13
EF2K	110	10
PKA	112	8