Inhibitor | AG490  

Screen Conc: 10.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
SGK1	18	2
DYRK1A	24	2
PIM3	25	1
MSK1	28	5
DYRK3	44	5
DYRK2	50	5
CHK2	52	6
PKB beta	52	7
MLK1	52	5
PIM1	53	0
Src	56	1
NUAK1	58	4
IRR	58	1
HER4	62	11
Aurora A	64	3
Aurora B	64	3
NEK2a	65	2
MLK3	65	6
MARK3	70	12
YES1	72	4
BRSK2	75	0
TTK	76	1
PRAK	77	4
MARK2	77	3
ROCK 2	78	4
GSK3 beta	78	3
MELK	79	4
p38 alpha MAPK	82	3
MKK1	82	9
HIPK2	83	0
ERK8	83	5
ERK1	83	13
HIPK1	85	1
TrkA	85	8
RSK1	85	11
BTK	85	13
BRSK1	85	5
VEGFR1	86	14
MST4	86	0
SYK	86	9
AMPK	87	9
EPH-B2	87	7
JNK1	88	5
CK1 delta	88	5
PAK2	88	11
IKK epsilon	88	0
PAK4	89	10
IKK beta	89	3
PRK2	91	8
JNK3	91	7
EF2K	91	5
PKD1	92	3
EPH-A2	92	5
SRPK1	92	2
FGF-R1	93	4
MINK1	93	6
PIM2	93	10
MKK6	93	12
EPH-B1	93	5
LKB1	94	11
SmMLCK	94	15
EPH-A4	94	10
DAPK1	94	11
p38 beta MAPK	95	0
NEK6	95	13
CSK	95	6
MARK1	95	5
RIPK2	96	11
S6K1	96	4
EPH-B4	97	6
Lck	97	2
MNK1	98	2
JAK2	98	4
MARK4	98	9
PHK	98	11
PKA	98	11
JNK2	99	6
CK2	99	5
p38 delta MAPK	99	3
PAK5	99	5
MEKK1	99	6
MST2	101	2
CLK2	102	5
MNK2	102	3
GCK	102	7
HIPK3	103	1
IRAK4	103	1
PDK1	103	6
ASK1	105	2
PKC zeta	105	5
ERK2	105	9
PAK6	106	4
CAMK1	106	4
PKC alpha	107	7
TBK1	107	2
RSK2	109	4
CAMKK beta	109	7
MKK2	109	2
CDK2-Cyclin A	111	11
MAPKAP-K2	112	10
IR	115	6
TAK1	116	1
EPH-B3	117	15
PKB alpha	117	4
CHK1	119	15
PLK1	119	4
IGF-1R	119	5
MAPKAP-K3	122	6
TAO1	125	10
p38 gamma MAPK	129	1

Screen Conc: 1.00µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
SGK1	54	4
MSK1	55	2
PIM3	70	6
DYRK2	71	0
PKB beta	71	7
MLK1	72	4
DYRK1A	74	1
Src	74	3
p38 alpha MAPK	75	4
MARK2	75	4
PAK4	76	3
SYK	76	1
MLK3	77	1
Aurora B	77	2
MELK	78	1
RSK1	78	4
HIPK1	79	6
NEK2a	79	8
MINK1	79	3
LKB1	80	3
SmMLCK	80	1
TTK	81	0
EF2K	82	1
TrkA	82	10
MKK1	82	10
ERK1	82	9
CHK1	83	10
VEGFR1	83	15
PRK2	83	3
NUAK1	84	15
TAK1	84	1
RSK2	84	8
MST2	84	1
BTK	84	3
TBK1	84	6
PIM1	84	7
ROCK 2	84	9
SRPK1	85	12
DAPK1	85	10
CHK2	85	12
CSK	85	0
EPH-B3	86	9
p38 beta MAPK	86	4
IRAK4	86	4
MAPKAP-K3	86	9
DYRK3	87	0
PAK6	87	8
MAPKAP-K2	87	7
GSK3 beta	88	6
HER4	88	1
MKK2	88	9
S6K1	89	2
EPH-A2	89	5
JNK1	89	15
TAO1	90	7
PKD1	90	12
CK1 delta	90	5
CLK2	90	13
PAK5	90	2
MKK6	90	5
MARK4	90	8
EPH-B1	91	7
EPH-B2	91	6
IRR	91	6
IKK epsilon	91	0
PKA	91	1
PLK1	92	7
PDK1	92	12
PRAK	92	1
GCK	92	6
JNK2	93	0
BRSK2	94	12
AMPK	94	11
p38 delta MAPK	96	9
MARK1	96	3
IKK beta	97	4
MARK3	97	3
PKC alpha	98	1
HIPK3	99	2
Aurora A	99	1
PKB alpha	99	3
EPH-A4	99	5
RIPK2	100	4
PAK2	100	9
BRSK1	100	5
CDK2-Cyclin A	101	8
IGF-1R	101	1
NEK6	101	12
PHK	102	7
ASK1	102	7
FGF-R1	102	11
ERK8	102	6
MST4	103	2
EPH-B4	104	9
JAK2	104	6
PIM2	104	13
Lck	105	1
HIPK2	106	4
IR	106	2
MNK2	106	5
YES1	106	0
CAMKK beta	106	4
ERK2	106	4
PKC zeta	107	4
JNK3	109	7
MEKK1	111	6
MNK1	112	0
CAMK1	113	5
CK2	114	1
p38 gamma MAPK	116	5