Inhibitor | A-443654  

Screen Conc: 0.10µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
PRK2	2	2
PKB beta	2	0
PKB alpha	3	2
PKA	3	1
DYRK1A	7	3
DYRK3	8	1
ROCK 2	8	1
MSK1	9	2
PIM3	13	1
PIM1	15	2
PIM2	15	2
PKD1	23	4
HIPK2	24	3
DYRK2	26	1
RSK2	27	3
SmMLCK	27	2
ERK8	28	3
PKC alpha	29	4
MST2	29	0
CDK2-Cyclin A	31	2
RSK1	32	1
S6K1	32	9
GSK3 beta	33	4
SGK1	53	5
PHK	54	6
ERK1	59	3
MELK	63	2
CAMKK beta	63	9
ERK2	64	2
PKC zeta	66	0
AMPK	67	3
MKK1	67	6
p38 delta MAPK	68	9
HIPK3	71	2
MAPKAP-K2	73	0
CK1 delta	74	3
CAMK1	77	6
JNK2	78	9
BRSK2	79	1
PDK1	79	8
PLK1	80	1
Aurora B	80	2
MNK2	80	5
p38 gamma MAPK	83	4
MARK3	83	1
NEK7	84	1
JNK3	86	8
Src	86	5
PAK6	87	3
IKK beta	89	2
CK2	90	8
PAK4	90	6
JNK1	90	3
SRPK1	91	2
p38 alpha MAPK	92	6
Aurora C	92	8
CSK	93	7
EF2K	94	8
CHK2	95	2
NEK6	95	4
NEK2a	95	2
MAPKAP-K3	96	2
PAK5	96	1
Lck	97	3
CHK1	99	2
p38 beta MAPK	105	4
PRAK	107	4
MNK1	109	2
CAMKK alpha	117	1

Screen Conc: 0.01µM

Kinase	% Activity Remaining Sort descending	Standard Deviation
PKB alpha	5	2
DYRK1A	10	2
PKB beta	17	2
PRK2	17	2
MSK1	19	2
PKA	26	1
DYRK3	41	3
ROCK 2	48	3
PIM3	54	6
PIM1	57	8
PIM2	59	0
ERK8	61	2
PKD1	63	3
SmMLCK	69	2
HIPK2	73	2
PKC alpha	73	3
RSK2	74	3
MST2	76	4
ERK1	77	8
RSK1	78	1
SGK1	78	2
ERK2	78	6
DYRK2	79	5
JNK3	81	9
GSK3 beta	81	1
Aurora B	81	3
PKC zeta	82	3
CDK2-Cyclin A	82	5
CAMKK beta	83	8
AMPK	84	8
MKK1	84	2
p38 delta MAPK	86	1
PHK	86	7
NEK7	86	8
PAK6	87	2
p38 gamma MAPK	87	5
BRSK2	88	9
PDK1	88	1
S6K1	88	3
CAMK1	89	3
JNK1	89	7
PLK1	89	5
HIPK3	90	0
MAPKAP-K3	91	9
Src	91	0
SRPK1	92	8
MAPKAP-K2	92	8
EF2K	93	7
IKK beta	93	8
JNK2	94	1
CHK2	94	8
CK1 delta	95	3
NEK6	95	2
MELK	96	2
CK2	96	0
MNK2	97	2
Lck	97	8
PAK4	99	3
CSK	99	2
Aurora C	100	4
MARK3	100	3
CHK1	100	3
NEK2a	101	5
PAK5	104	2
PRAK	107	3
CAMKK alpha	112	2
p38 beta MAPK	114	3
MNK1	120	3
p38 alpha MAPK	131	2