Inhibitor | A-83-01  

Screen Conc: 0.10µM

Kinase Sort descending	% Activity Remaining	Standard Deviation
AMPK	99	3
Aurora A	120	7
Aurora B	98	5
BRSK1	110	12
BRSK2	117	6
BTK	110	5
CAMK1	103	18
CAMKK beta	100	10
CDK2-Cyclin A	93	4
CHK1	107	10
CHK2	115	10
CK1 delta	90	8
CK2	102	0
CLK2	106	10
CSK	97	2
DAPK1	94	3
DYRK1A	109	11
DYRK2	100	0
DYRK3	102	8
EF2K	102	4
EPH-A2	105	5
EPH-A4	108	1
EPH-B2	113	2
EPH-B3	112	6
EPH-B4	93	2
ERK1	105	15
ERK2	104	11
ERK8	108	16
FGF-R1	64	3
GCK	98	3
GSK3 beta	99	1
HER4	104	1
HIPK1	96	4
HIPK2	104	8
HIPK3	105	8
IGF-1R	97	5
IKK beta	107	1
IKK epsilon	112	5
IR	108	7
IRAK4	101	3
IRR	98	5
JAK2	107	18
JNK1	111	3
JNK2	105	6
JNK3	119	3
Lck	105	7
LKB1	101	5
MAPKAP-K2	117	3
MAPKAP-K3	107	3
MARK1	107	3
MARK2	121	8
MARK3	101	4
MARK4	98	2
MEKK1	130	15
MELK	111	2
MINK1	66	2
MKK1	111	20
MLK1	96	7
MLK3	104	2
MNK1	103	1
MNK2	81	5
MSK1	110	6
MST2	107	0
MST4	95	2
NEK2a	109	8
NEK6	107	3
NUAK1	96	10
p38 alpha MAPK	56	1
p38 beta MAPK	89	15
p38 delta MAPK	91	20
p38 gamma MAPK	102	13
PAK2	111	17
PAK4	89	6
PAK5	107	2
PAK6	111	12
PDK1	103	8
PHK	100	11
PIM1	105	3
PIM2	97	4
PIM3	91	4
PKA	109	2
PKB alpha	102	5
PKB beta	108	3
PKC alpha	97	5
PKC zeta	98	0
PKD1	80	1
PLK1	99	11
PRAK	113	7
PRK2	105	12
RIPK2	26	6
ROCK 2	96	2
RSK1	110	6
RSK2	126	3
S6K1	108	2
SGK1	107	1
SmMLCK	104	8
Src	102	1
SRPK1	101	7
SYK	109	10
TAK1	99	9
TBK1	102	7
TrkA	118	2
TTK	113	0
VEGFR1	27	0
YES1	106	4

Screen Conc: 1.00µM

Kinase Sort descending	% Activity Remaining	Standard Deviation
AMPK	82	4
Aurora A	107	3
Aurora B	102	1
BRSK1	95	7
BRSK2	92	14
BTK	104	5
CAMK1	107	13
CAMKK beta	104	2
CDK2-Cyclin A	102	11
CHK1	105	3
CHK2	110	6
CK1 delta	46	5
CK2	104	11
CLK2	98	0
CSK	93	1
DAPK1	90	2
DYRK1A	104	1
DYRK2	95	7
DYRK3	93	4
EF2K	100	3
EPH-A2	92	14
EPH-A4	98	3
EPH-B2	95	5
EPH-B3	104	0
EPH-B4	93	19
ERK1	100	5
ERK2	94	2
ERK8	93	4
FGF-R1	37	2
GCK	68	7
GSK3 beta	79	4
HER4	82	15
HIPK1	98	11
HIPK2	95	12
HIPK3	99	1
IGF-1R	103	11
IKK beta	100	12
IKK epsilon	106	0
IR	94	6
IRAK4	99	5
IRR	103	3
JAK2	93	4
JNK1	101	4
JNK2	90	7
JNK3	99	7
Lck	62	3
LKB1	99	11
MAPKAP-K2	108	2
MAPKAP-K3	97	4
MARK1	113	7
MARK2	110	9
MARK3	98	7
MARK4	87	2
MEKK1	111	0
MELK	105	3
MINK1	13	2
MKK1	98	1
MLK1	86	2
MLK3	107	4
MNK1	93	1
MNK2	91	2
MSK1	101	0
MST2	100	6
MST4	99	1
NEK2a	92	3
NEK6	100	5
NUAK1	84	4
p38 alpha MAPK	16	1
p38 beta MAPK	61	7
p38 delta MAPK	94	4
p38 gamma MAPK	88	8
PAK2	101	12
PAK4	93	4
PAK5	102	4
PAK6	113	19
PDK1	88	0
PHK	112	4
PIM1	97	4
PIM2	94	3
PIM3	117	11
PKA	99	5
PKB alpha	106	9
PKB beta	96	5
PKC alpha	102	7
PKC zeta	100	3
PKD1	32	9
PLK1	106	7
PRAK	99	16
PRK2	91	3
RIPK2	9	3
ROCK 2	104	2
RSK1	95	2
RSK2	109	8
S6K1	105	13
SGK1	103	14
SmMLCK	89	1
Src	75	1
SRPK1	84	1
SYK	106	2
TAK1	81	9
TBK1	106	1
TrkA	99	11
TTK	98	6
VEGFR1	8	1
YES1	70	5