Inhibitor | AG1478 (Tyrphostin)  

Screen Conc: 1.00µM

Kinase Sort descending	% Activity Remaining	Standard Deviation
AMPK	80	8
ASK1	104	1
Aurora A	82	6
Aurora B	53	3
BRSK1	74	9
BRSK2	79	4
BTK	69	0
CAMK1	106	6
CAMKK beta	97	1
CDK2-Cyclin A	112	7
CHK1	81	4
CHK2	81	5
CK1 delta	100	5
CK2	99	0
CLK2	95	3
CSK	86	9
DAPK1	88	2
DYRK1A	90	5
DYRK2	74	3
DYRK3	76	6
EF2K	88	3
EPH-A2	77	1
EPH-A4	58	1
EPH-B1	107	13
EPH-B2	57	10
EPH-B3	63	11
EPH-B4	67	2
ERK1	84	11
ERK2	94	5
ERK8	96	9
FGF-R1	75	1
GCK	82	2
GSK3 beta	90	13
HER4	25	0
HIPK1	93	7
HIPK2	100	4
HIPK3	101	0
IGF-1R	104	13
IKK beta	90	4
IKK epsilon	82	4
IR	105	5
IRAK4	38	0
IRR	93	5
JAK2	61	1
JNK1	100	0
JNK2	79	3
JNK3	76	6
Lck	54	2
LKB1	93	11
MAPKAP-K2	81	6
MAPKAP-K3	88	2
MARK1	101	4
MARK2	79	6
MARK3	83	3
MARK4	104	14
MEKK1	88	5
MELK	91	7
MINK1	62	4
MKK1	94	1
MKK2	84	7
MKK6	103	4
MLK1	63	3
MLK3	53	5
MNK1	44	3
MNK2	47	4
MSK1	87	7
MST2	76	0
MST4	100	12
NEK2a	86	6
NEK6	90	2
NUAK1	80	5
p38 alpha MAPK	37	2
p38 beta MAPK	68	10
p38 delta MAPK	99	4
p38 gamma MAPK	98	3
PAK2	101	11
PAK4	98	5
PAK5	90	0
PAK6	99	4
PDK1	92	5
PHK	85	3
PIM1	79	14
PIM2	102	2
PIM3	75	12
PKA	97	15
PKB alpha	102	9
PKB beta	69	11
PKC alpha	79	7
PKC zeta	104	6
PKD1	87	3
PLK1	104	3
PRAK	87	0
PRK2	86	3
RIPK2	10	1
ROCK 2	86	2
RSK1	82	2
RSK2	83	7
S6K1	82	2
SGK1	106	3
SmMLCK	49	0
Src	39	1
SRPK1	98	5
SYK	110	3
TAK1	91	7
TAO1	93	8
TBK1	83	1
TrkA	65	9
TTK	83	2
VEGFR1	31	0
YES1	42	4

Screen Conc: 10.00µM

Kinase Sort descending	% Activity Remaining	Standard Deviation
AMPK	68	1
Aurora A	15	0
Aurora B	46	5
BRSK1	40	2
BRSK2	41	3
BTK	15	0
CAMK1	94	1
CAMKK beta	52	2
CDK2-Cyclin A	91	8
CHK1	78	4
CHK2	23	0
CK1 delta	65	11
CK2	90	2
CSK	57	13
DYRK1A	45	2
DYRK2	33	3
DYRK3	23	3
EF2K	113	6
EPH-A2	18	0
EPH-B3	63	0
ERK1	75	0
ERK2	39	6
ERK8	61	9
FGF-R1	44	5
GCK	43	2
GSK3 beta	75	5
HER4	3	1
HIPK1	120	59
HIPK2	76	2
HIPK3	96	2
IGF-1R	95	7
IKK beta	89	0
IKK epsilon	67	3
IR	81	2
IRAK4	11	0
IRR	78	0
JNK1	105	7
JNK2	78	7
JNK3	73	8
Lck	34	0
LKB1	99	19
MAPKAP-K2	89	4
MAPKAP-K3	98	4
MARK2	102	3
MARK3	61	0
MARK4	79	4
MELK	55	0
MINK1	14	0
MKK1	52	0
MLK1	24	0
MLK3	75	14
MNK1	7	0
MNK2	36	5
MSK1	96	2
MST2	35	0
MST4	62	21
NEK2a	82	3
NEK6	100	1
NUAK1	39	4
p38 alpha MAPK	12	1
p38 beta MAPK	38	0
p38 delta MAPK	97	6
p38 gamma MAPK	105	9
PAK2	85	0
PAK4	87	6
PAK5	81	2
PAK6	98	1
PDK1	79	5
PHK	23	3
PIM1	40	5
PIM2	96	3
PIM3	29	4
PKA	107	7
PKB alpha	86	10
PKB beta	93	10
PKC alpha	74	3
PKC zeta	106	7
PKD1	32	2
PLK1	74	10
PRAK	88	12
PRK2	111	3
RIPK2	14	3
ROCK 2	61	9
RSK1	74	14
RSK2	82	1
S6K1	86	1
SGK1	83	6
SmMLCK	14	0
Src	8	1
SRPK1	98	2
SYK	107	3
TBK1	40	7
TTK	79	1
VEGFR1	5	0
YES1	5	0