Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SGK1-Sanofi-ex.290-R C24H25ClN6O5S 545.01 SGK1 WO201414006 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 66 8
MKK2 41 11
MKK6 102 17
ERK1 115 16
ERK2 109 8
ERK5 84 13
JNK1 101 6
JNK2 105 2
JNK3 104 25
p38 alpha MAPK 111 2
p38 beta MAPK 99 3
p38 gamma MAPK 112 3
p38 delta MAPK 111 7
ERK8 18 0
RSK1 7 0
RSK2 24 2
PDK1 117 34
PKB alpha 49 1
PKB beta 55 7
SGK1 2 1
S6K1 1 0
PKA 85 6
ROCK 2 105 7
PRK2 76 6
PKC alpha 113 4
PKC gamma 101 9
PKC zeta 110 17
PKD1 15 4
STK33 74 2
MSK1 10 1
MNK1 87 5
MNK2 119 23
MAPKAP-K2 87 16
MAPKAP-K3 105 27
PRAK 78 11
CAMKK beta 77 5
CAMK1 3 0
SmMLCK 23 4
PHK 97 10
DAPK1 87 8
CHK1 95 15
CHK2 9 3
GSK3 beta 90 7
CDK2-Cyclin A 94 14
CDK9-Cyclin T1 105 10
PLK1 102 4
Aurora A 108 12
Aurora B 70 1
TLK1 89 12
LKB1 106 22
AMPK (hum) 15 1
MARK1 115 19
MARK2 113 9
MARK3 89 3
MARK4 98 10
BRSK1 95 3
BRSK2 102 8
MELK 11 0
NUAK1 91 11
SIK2 91 1
SIK3 102 9
TSSK1 98 8
CK1 gamma 2 112 9
CK1 delta 65 5
CK2 100 6
TTBK1 109 16
TTBK2 114 10
DYRK1A 103 10
DYRK2 100 2
DYRK3 89 13
NEK2a 74 5
NEK6 88 2
IKK beta 102 0
IKK epsilon 34 5
TBK1 62 3
PIM1 83 24
PIM2 105 3
PIM3 105 11
SRPK1 94 6
EF2K 112 14
EIF2AK3 66 0
HIPK1 117 10
HIPK2 50 6
HIPK3 109 9
CLK2 88 1
PAK2 90 7
PAK4 91 8
PAK5 110 5
PAK6 94 13
MST2 105 23
MST3 57 17
MST4 50 6
GCK 90 13
MAP4K3 2 0
MAP4K5 19 3
MINK1 101 14
MEKK1 112 6
MLK1 9 2
MLK3 10 4
TESK1 77 2
TAO1 110 8
ASK1 104 1
TAK1 101 12
IRAK1 93 2
IRAK4 74 12
RIPK2 124 16
OSR1 110 4
TTK 76 3
MPSK1 82 6
WNK1 110 7
ULK1 78 2
ULK2 46 2
TGFBR1 120 15
Src 104 16
Lck 89 7
CSK 66 5
YES1 92 12
ABL 88 1
BTK 91 10
JAK2 112 14
SYK 88 20
ZAP70 98 7
TIE2 17 10
BRK 113 9
EPH-A2 109 10
EPH-A4 95 22
EPH-B1 117 10
EPH-B2 120 6
EPH-B3 104 21
EPH-B4 103 11
FGF-R1 104 3
HER4 102 17
IGF-1R 88 2
IR 102 8
IRR 96 13
TrkA 104 0
DDR2 80 1
VEGFR1 82 26
PDGFRA 91 8
PINK 99 13

Do you need any help? Please get in touch and we’ll be happy to lend a hand.