Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SGK1-Sanofi-ex.290-S C24H25ClN6O5S 545.01 SGK1 WO2014140065 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 76 15
MKK2 42 11
MKK6 105 13
ERK1 108 19
ERK2 116 13
ERK5 86 15
JNK1 98 1
JNK2 107 15
JNK3 117 42
p38 alpha MAPK 102 1
p38 beta MAPK 103 1
p38 gamma MAPK 118 3
p38 delta MAPK 107 3
ERK8 16 3
RSK1 7 1
RSK2 26 2
PDK1 97 6
PKB alpha 84 3
PKB beta 87 8
SGK1 2 1
S6K1 0 0
PKA 86 7
ROCK 2 109 1
PRK2 80 2
PKC alpha 109 6
PKC gamma 108 1
PKC zeta 115 1
PKD1 21 5
STK33 69 8
MSK1 19 1
MNK1 89 4
MNK2 83 2
MAPKAP-K2 101 11
MAPKAP-K3 97 13
PRAK 99 11
CAMKK beta 86 7
CAMK1 4 0
SmMLCK 39 7
PHK 99 13
DAPK1 105 9
CHK1 77 11
CHK2 10 0
GSK3 beta 94 8
CDK2-Cyclin A 97 15
CDK9-Cyclin T1 98 6
PLK1 95 21
Aurora A 129 2
Aurora B 56 11
TLK1 100 12
LKB1 118 31
AMPK (hum) 39 10
MARK1 119 7
MARK2 110 10
MARK3 94 5
MARK4 100 6
BRSK1 92 3
BRSK2 103 19
MELK 12 1
NUAK1 85 4
SIK2 93 10
SIK3 100 5
TSSK1 96 14
CK1 gamma 2 122 2
CK1 delta 69 4
CK2 94 1
TTBK1 96 3
TTBK2 109 14
DYRK1A 95 9
DYRK2 107 15
DYRK3 90 8
NEK2a 87 12
NEK6 110 6
IKK beta 104 4
IKK epsilon 44 5
TBK1 74 7
PIM1 87 0
PIM2 100 3
PIM3 101 13
SRPK1 102 4
EF2K 106 12
EIF2AK3 87 8
HIPK1 110 2
HIPK2 50 3
HIPK3 108 16
CLK2 89 2
PAK2 104 8
PAK4 97 2
PAK5 108 10
PAK6 91 7
MST2 93 4
MST3 56 9
MST4 62 5
GCK 114 6
MAP4K3 4 1
MAP4K5 18 4
MINK1 106 6
MEKK1 107 12
MLK1 32 5
MLK3 30 4
TESK1 87 11
TAO1 95 13
ASK1 109 15
TAK1 108 10
IRAK1 89 14
IRAK4 85 18
RIPK2 112 9
OSR1 112 8
TTK 77 5
MPSK1 97 3
WNK1 114 17
ULK1 79 3
ULK2 78 7
TGFBR1 108 17
Src 102 21
Lck 91 2
CSK 106 3
YES1 105 9
ABL 93 3
BTK 93 0
JAK2 114 2
SYK 105 11
ZAP70 105 32
TIE2 29 10
BRK 107 23
EPH-A2 120 19
EPH-A4 101 21
EPH-B1 115 5
EPH-B2 136 9
EPH-B3 115 22
EPH-B4 99 6
FGF-R1 104 2
HER4 97 11
IGF-1R 102 4
IR 101 3
IRR 131 42
TrkA 111 8
DDR2 90 3
VEGFR1 100 11
PDGFRA 106 15
PINK 114 9

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