Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SGK1-Sanofi-308-R C23H23FN6O4S 498.53 SGK1 WO2014140065 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 62 2
MKK2 80 9
MKK6 66 8
ERK1 106 40
ERK2 110 19
ERK5 73 5
JNK1 112 9
JNK2 113 4
JNK3 112 8
p38 alpha MAPK 88 11
p38 beta MAPK 116 17
p38 gamma MAPK 111 6
p38 delta MAPK 126 9
ERK8 49 8
RSK1 7 0
RSK2 24 2
PDK1 88 24
PKB alpha 96 1
PKB beta 35 9
SGK1 10 3
S6K1 1 0
PKA 106 6
ROCK 2 74 10
PRK2 82 4
PKC alpha 135 19
PKC gamma 90 7
PKC zeta 72 8
PKD1 37 8
STK33 36 3
MSK1 7 0
MNK1 77 14
MNK2 78 2
MAPKAP-K2 83 4
MAPKAP-K3 83 35
PRAK 86 12
CAMKK beta 106 4
CAMK1 22 14
SmMLCK 74 5
PHK 83 11
DAPK1 91 20
CHK1 109 13
CHK2 24 1
GSK3 beta 92 6
CDK2-Cyclin A 61 21
CDK9-Cyclin T1 63 3
PLK1 86 3
Aurora A 109 5
Aurora B 115 1
TLK1 108 6
LKB1 96 10
AMPK (hum) 78 3
MARK1 109 17
MARK2 94 48
MARK3 103 1
MARK4 73 35
BRSK1 106 13
BRSK2 82 9
MELK 19 6
NUAK1 103 8
SIK2 55 11
SIK3 69 1
TSSK1 94 10
CK1 gamma 2 67 9
CK1 delta 121 12
CK2 103 1
TTBK1 91 24
TTBK2 87 13
DYRK1A 81 21
DYRK2 74 13
DYRK3 99 14
NEK2a 67 1
NEK6 91 28
IKK beta 67 0
IKK epsilon 26 4
TBK1 83 51
PIM1 104 10
PIM2 127 46
PIM3 76 1
SRPK1 119 15
EF2K 128 1
EIF2AK3 63 7
HIPK1 73 22
HIPK2 47 7
HIPK3 44 18
CLK2 104 9
PAK2 53 3
PAK4 102 11
PAK5 83 0
PAK6 80 36
MST2 86 4
MST3 79 10
MST4 98 7
GCK 80 1
MAP4K3 8 1
MAP4K5 63 28
MINK1 83 7
MEKK1 115 32
MLK1 16 1
MLK3 24 6
TESK1 69 23
TAO1 123 23
ASK1 87 8
TAK1 74 23
IRAK1 88 11
IRAK4 105 0
RIPK2 122 13
OSR1 75 4
TTK 91 7
MPSK1 116 3
WNK1 75 19
ULK1 103 8
ULK2 59 2
TGFBR1 120 2
Src 131 0
Lck 98 7
CSK 96 7
YES1 71 8
ABL 96 20
BTK 59 2
JAK2 94 1
SYK 100 9
ZAP70 101 7
TIE2 51 1
BRK 86 26
EPH-A2 113 2
EPH-A4 53 12
EPH-B1 96 3
EPH-B2 56 49
EPH-B3 64 5
EPH-B4 124 9
FGF-R1 115 5
HER4 67 74
IGF-1R 95 2
IR 110 2
IRR 106 11
TrkA 71 1
DDR2 106 6
VEGFR1 95 19
PDGFRA 115 3
PINK 119 6

Do you need any help? Please get in touch and we’ll be happy to lend a hand.