Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SGK1-Sanofi-14n C17H12CIFN6O2S 418.83 SGK Halland, N (2015) ACS Medicinal Chemistry Letters 6 73-78 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 77 10
MKK2 80 9
MKK6 94 10
ERK1 99 2
ERK2 94 3
ERK5 101 5
JNK1 104 6
JNK2 90 4
JNK3 89 9
p38 alpha MAPK 92 13
p38 beta MAPK 92 15
p38 gamma MAPK 98 9
p38 delta MAPK 90 13
ERK8 51 25
RSK1 56 2
RSK2 79 17
PDK1 104 16
PKB alpha 93 5
PKB beta 102 28
SGK1 6 3
S6K1 2 0
PKA 102 11
ROCK 2 105 0
PRK2 98 7
PKC alpha 102 9
PKC gamma 99 8
PKC zeta 91 7
PKD1 87 3
STK33 88 2
MSK1 41 7
MNK1 80 2
MNK2 79 1
MAPKAP-K2 104 12
MAPKAP-K3 110 6
PRAK 112 26
CAMKK beta 94 1
CAMK1 56 1
SmMLCK 104 3
PHK 105 1
DAPK1 110 10
CHK1 97 5
CHK2 64 6
GSK3 beta 95 7
CDK2-Cyclin A 101 2
CDK9-Cyclin T1 115 1
PLK1 93 21
Aurora A 110 3
Aurora B 39 3
TLK1 109 8
LKB1 90 0
AMPK (hum) 79 8
MARK1 106 5
MARK2 105 1
MARK3 113 13
MARK4 93 1
BRSK1 94 7
BRSK2 91 1
MELK 78 2
NUAK1 64 7
SIK2 98 1
SIK3 94 6
TSSK1 94 2
CK1 gamma 2 95 14
CK1 delta 102 6
CK2 100 4
TTBK1 101 5
TTBK2 107 7
DYRK1A 97 10
DYRK2 101 6
DYRK3 95 14
NEK2a 96 2
NEK6 91 5
IKK beta 102 4
IKK epsilon 67 1
TBK1 83 3
PIM1 103 0
PIM2 110 12
PIM3 92 3
SRPK1 93 1
EF2K 98 10
EIF2AK3 83 4
HIPK1 96 15
HIPK2 64 8
HIPK3 102 5
CLK2 90 10
PAK2 113 13
PAK4 47 5
PAK5 81 4
PAK6 86 0
MST2 95 3
MST3 98 9
MST4 102 3
GCK 34 9
MAP4K3 39 3
MAP4K5 34 1
MINK1 75 8
MEKK1 104 3
MLK1 8 2
MLK3 6 1
TESK1 108 1
TAO1 77 3
ASK1 142 4
TAK1 38 0
IRAK1 100 0
IRAK4 100 6
RIPK2 108 16
OSR1 95 4
TTK 72 2
MPSK1 93 15
WNK1 102 1
ULK1 99 3
ULK2 89 1
TGFBR1 80 10
Src 109 25
Lck 101 8
CSK 100 8
YES1 88 0
ABL 105 35
BTK 83 2
JAK2 80 9
SYK 88 2
ZAP70 90 11
TIE2 10 3
BRK 103 12
EPH-A2 108 6
EPH-A4 94 2
EPH-B1 114 5
EPH-B2 104 2
EPH-B3 99 4
EPH-B4 109 17
FGF-R1 109 7
HER4 119 5
IGF-1R 82 16
IR 98 10
IRR 100 6
TrkA 108 3
DDR2 101 1
VEGFR1 80 12
PDGFRA 73 2
PINK 107 8

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